Search Results - "Rath, Sandip K"
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SAMHD1 deacetylation by SIRT1 promotes DNA end resection by facilitating DNA binding at double-strand breaks
Published in Nature communications (07-11-2022)“…Sterile alpha motif and HD domain-containing protein 1 (SAMHD1) has a dNTPase-independent function in promoting DNA end resection to facilitate DNA…”
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DNA-PK is activated by SIRT2 deacetylation to promote DNA double-strand break repair by non-homologous end joining
Published in Nucleic acids research (25-08-2023)“…Abstract DNA-dependent protein kinase (DNA-PK) plays a critical role in non-homologous end joining (NHEJ), the predominant pathway that repairs DNA…”
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miR-132-3p and KLF7 as novel regulators of aortic stiffening-associated EndMT in type 2 diabetes mellitus
Published in Diabetology and metabolic syndrome (25-01-2023)“…The prevalence of diabetes mellitus has risen considerably and currently affects more than 422 million people worldwide. Cardiovascular diseases including…”
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SAMHD1 expression contributes to doxorubicin resistance and predicts survival outcomes in diffuse large B-cell lymphoma patients
Published in NAR cancer (01-03-2024)“…Diffuse large B-cell lymphoma (DLBCL) is a commonly diagnosed, aggressive non-Hodgkin's lymphoma. While R-CHOP chemoimmunotherapy is potentially curative,…”
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Chromatin dynamics: H3K4 methylation and H3 variant replacement during development and in cancer
Published in Cellular and molecular life sciences : CMLS (01-09-2014)“…The dynamic nature of chromatin and its myriad modifications play a crucial role in gene regulation (expression and repression) during development, cellular…”
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Causal Connections From Chronic Kidney Disease to Cardiac Fibrosis
Published in Seminars in nephrology (01-11-2018)“…Cardiovascular disease and heart failure are the primary cause of morbidity and mortality in patients with chronic kidney disease. Because impairment of kidney…”
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