Search Results - "Rath, Michaela"
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The myokine decorin is regulated by contraction and involved in muscle hypertrophy
Published in Biochemical and biophysical research communications (25-07-2014)“…•The myokine decorin is regulated by skeletal muscle contraction in mice and humans.•Acute resistance exercise increases plasma decorin levels in…”
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2
Insulin action in the brain regulates mitochondrial stress responses and reduces diet-induced weight gain
Published in Molecular metabolism (Germany) (01-03-2019)“…Insulin action in the brain controls metabolism and brain function, which is linked to proper mitochondrial function. Conversely, brain insulin resistance…”
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3
HSP60 reduction protects against diet-induced obesity by modulating energy metabolism in adipose tissue
Published in Molecular metabolism (Germany) (01-11-2021)“…Insulin regulates mitochondrial function, thereby propagating an efficient metabolism. Conversely, diabetes and insulin resistance are linked to mitochondrial…”
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4
Regional differences in brain glucose metabolism determined by imaging mass spectrometry
Published in Molecular metabolism (Germany) (01-06-2018)“…Glucose is the major energy substrate of the brain and crucial for normal brain function. In diabetes, the brain is subject to episodes of hypo- and…”
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5
Pknox1/Prep1 Regulates Mitochondrial Oxidative Phosphorylation Components in Skeletal Muscle
Published in Molecular and Cellular Biology (01-01-2014)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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6
Obesity Hinders the Protective Effect of Selenite Supplementation on Insulin Signaling
Published in Antioxidants (28-04-2022)“…The intake of high-fat diets (HFDs) containing large amounts of saturated long-chain fatty acids leads to obesity, oxidative stress, inflammation, and insulin…”
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7
Central Acting Hsp10 Regulates Mitochondrial Function, Fatty Acid Metabolism, and Insulin Sensitivity in the Hypothalamus
Published in Antioxidants (30-04-2021)“…Mitochondria are critical for hypothalamic function and regulators of metabolism. Hypothalamic mitochondrial dysfunction with decreased mitochondrial chaperone…”
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8
Genetic Ablation of cGMP-Dependent Protein Kinase Type I Causes Liver Inflammation and Fasting Hyperglycemia
Published in Diabetes (New York, N.Y.) (01-05-2011)“…The nitric oxide/cGMP/cGMP-dependent protein kinase type I (cGKI) signaling pathway regulates cell functions that play a pivotal role in the pathogenesis of…”
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145-OR: Selenite Treatment Impacts Adipocyte Metabolism and Counteracts Detrimental Effects of Diet-Induced Insulin Resistance
Published in Diabetes (New York, N.Y.) (01-06-2022)“…The loss of insulin receptor (IR) in white adipose tissue (WAT) is a feature of type 2 diabetes. Previously, we have demonstrated that feeding mice a…”
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1398-P: Lactobacillus rhamnosus Attenuates Depressive-Like Behavior in High-Fat Diet Fed Mice and Regulates Tyrosine Hydroxylase
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Prevalence of depression is higher in diabetic patients compared to healthy humans due to a shared pathogenesis including insulin resistance and inflammation…”
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1536-P: DEP-1 Is a Novel Modulator of Brain Energy Metabolism
Published in Diabetes (New York, N.Y.) (01-06-2024)“…Obesity's metabolic impact goes beyond peripheral insulin resistance, influencing the brain and thereby disrupting energy homeostasis by altering anabolic and…”
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Hypothalamic HSP10 Impacts Mitochondrial Dynamics, Insulin Signaling, and Liver Glycogen Content
Published in Diabetes (New York, N.Y.) (01-07-2018)“…The mitochondrial chaperones heat shock protein 10 (HSP10) and 60 enable proper protein folding and thereby facilitate mitochondrial function. Previously, we…”
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13
Lactobacillus rhamnosus Sex-Specifically Attenuates Depressive-like Behavior and Mitigates Metabolic Consequences in Obesity
Published in Biological psychiatry global open science (01-10-2023)“…Patients with diabetes exhibit an increased prevalence for emotional disorders compared with healthy humans, partially due to a shared pathogenesis including…”
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14
Insulin secretion stimulated by L-arginine and its metabolite L-ornithine depends on Gα(i2)
Published in American journal of physiology: endocrinology and metabolism (01-11-2014)“…Bordetella pertussis toxin (PTx), also known as islet-activating protein, induces insulin secretion by ADP-ribosylation of inhibitory G proteins. PTx-induced…”
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15
Beech trees fuel soil animal food webs via root-derived nitrogen
Published in Basic and applied ecology (01-08-2017)“…•Soil animals incorporated root-derived C in the ash but not in the beech rhizosphere.•All soil animal species investigated differentially incorporated…”
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GPx3 dysregulation impacts adipose tissue insulin receptor expression and sensitivity
Published in JCI insight (04-06-2020)“…Insulin receptor signaling is crucial for white adipose tissue (WAT) function. Consequently, lack of insulin receptor (IR) in WAT results in a diabetes-like…”
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Role of Medium- and Short-Chain L-3-Hydroxyacyl-CoA Dehydrogenase in the Regulation of Body Weight and Thermogenesis
Published in Endocrinology (Philadelphia) (01-12-2011)“…Dysregulation of fatty acid oxidation plays a pivotal role in the pathophysiology of obesity and insulin resistance. Medium- and…”
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18
The HPA axis modulates the CNS melanocortin control of liver triacylglyceride metabolism
Published in Physiology & behavior (01-02-2012)“…Abstract The central melanocortin system regulates lipid metabolism in peripheral tissues such as white adipose tissue. Alterations in the activity of…”
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