Search Results - "Rath, Kellie S"

Burnout and associated factors among members of the Society of Gynecologic Oncology by Rath, Kellie S., MD, Huffman, Laura B., MD, Phillips, Gary S., MS, Carpenter, Kristen M., PhD, Fowler, Jeffrey M., MD

“…Objective Burnout is specific to the work domain and in physicians is indicative of emotional exhaustion, depersonalization in relationships with coworkers and…”
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HO-3867, a Safe STAT3 Inhibitor, Is Selectively Cytotoxic to Ovarian Cancer by RATH, Kellie S, NAIDU, Shan K, HOUGHTON, Peter, HIDEG, Kálmán, KUPPUSAMY, Periannan, COHN, David E, SELVENDIRAN, Karuppaiyah, LATA, Pushpa, BID, Hemant K, RIVERA, Brian K, MCCANN, Georgia A, TIERNEY, Brent J, ELNAGGAR, Adam C, BRAVO, Veronica, LEONE, Gustavo

“…STAT3 is well corroborated preclinically as a cancer therapeutic target, but tractable translational strategies for its blockade by small molecule inhibitors…”
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Bortezomib-Induced Unfolded Protein Response Increases Oncolytic HSV-1 Replication Resulting in Synergistic Antitumor Effects by JI YOUNG YOO, HURWITZ, Brian S, CRIPE, Timothy P, PARRIS, Deborah S, CALIGIURI, Michael A, JIANHUA YU, OLD, Matthew, KAUR, Balveen, BOLYARD, Chelsea, YU, Jun-Ge, JIANYING ZHANG, SELVENDIRAN, Karuppaiyah, RATH, Kellie S, SHUN HE, BAILEY, Zachary, EAVES, David

“…Bortezomib is an FDA-approved proteasome inhibitor, and oncolytic herpes simplex virus-1 (oHSV) is a promising therapeutic approach for cancer. We tested the…”
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Aberrantly activated pSTAT3-Ser727 in human endometrial cancer is suppressed by HO-3867, a novel STAT3 inhibitor by Tierney, Brent J, McCann, Georgia A, Naidu, Shan, Rath, Kellie S, Saini, Uksha, Wanner, Ross, Kuppusamy, Periannan, Suarez, Adrian, Goodfellow, Paul J, Cohn, David E, Selvendiran, Karuppaiyah

“…Abstract Objective Constitutive activation of STAT3 is a hallmark of various human cancers, however an increased pSTAT3 expression in high grade human…”
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Expression of soluble interleukin-6 receptor in malignant ovarian tissue by Rath, Kellie S., MD, Funk, Holly M., BSc, Bowling, Marcia C., MD, Richards, William E., MD, Drew, Angela F., PhD

“…Objective The objective of the study was to investigate interleukin-6 receptor (IL6R) isoforms and sheddases in the ovarian tumor microenvironment. Study…”
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Training the Next Generation of Robotic Surgeons Using Guided Mentorship: A Randomized Controlled Trial by Liang, Margaret I., MD, McCann, Georgia A., MD, Rath, Kellie S., MD, Backes, Floor J., MD, Cansino, Catherine, MD, MPH, Salani, Ritu, MD, MBA

“…Abstract Study Objective To evaluate the effect of expert guided mentorship on technical score and time for a set of robotic training drills. Design…”
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Targeting constitutively-activated STAT3 in hypoxic ovarian cancer, using a novel STAT3 inhibitor by McCann, Georgia A, Naidu, Shan, Rath, Kellie S, Bid, Hemant K, Tierney, Brent J, Suarez, Adrian, Varadharaj, Saradhadevi, Zhang, Jianying, Hideg, Kálmán, Houghton, Peter, Kuppusamy, Periannan, Cohn, David E, Selvendiran, Karuppaiyah

“…Tumor hypoxia, a feature of many solid tumors including ovarian cancer, is associated with resistance to therapies. We previously demonstrated that hypoxic…”
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Predicting Inpatient Stay Lasting 2 Midnights or Longer After Robotic Surgery for Endometrial Cancer by Liang, Margaret I., MD, Rosen, Maggie A., MD, Rath, Kellie S., MD, Hade, Erinn M., PhD, Clements, Aine E., MD, Backes, Floor J., MD, Eisenhauer, Eric L., MD, Salani, Ritu, MD, O'Malley, David M., MD, Fowler, Jeffrey M., MD, Cohn, David E., MD

“…Abstract Objective To estimate the rate of inpatient stay and the factors predicting inpatient status after robotic surgery for endometrial cancer following…”
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Stress and burnout among gynecologic oncologists: A Society of Gynecologic Oncology Evidence-based Review and Recommendations by Cass, Ilana, Duska, Linda R, Blank, Stephanie V, Cheng, Georgina, duPont, Nefertiti C, Frederick, Peter J, Hill, Emily K, Matthews, Carolyn M, Pua, Tarah L, Rath, Kellie S, Ruskin, Rachel, Thaker, Premal H, Berchuck, Andrew, Gostout, Bobbie S, Kushner, David M, Fowler, Jeff M

“…Highlights • There is a high prevalence of burnout among gynecologic oncologists. • Physician burnout is associated with significant personal distress. • There…”
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Doxorubicin synergizes with 34.5ENVE to enhance antitumor efficacy against metastatic ovarian cancer by Bolyard, Chelsea, Yoo, Ji Young, Wang, Pin-Yi, Saini, Uksha, Rath, Kellie S, Cripe, Timothy P, Zhang, Jianying, Selvendiran, Karuppaiyah, Kaur, Balveen

“…Novel therapeutic regimens are needed to improve dismal outcomes associated with late-stage ovarian cancer. Oncolytic viruses are currently being tested in…”
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Reducing readmissions after robotic surgical management of endometrial cancer:A potential for improved quality care by Liang, Margaret I, Rosen, Maggie A, Rath, Kellie S, Clements, Aine E, Backes, Floor J, Eisenhauer, Eric L, Salani, Ritu, O'Malley, David M, Fowler, Jeffrey M, Cohn, David E

“…Abstract Objective To describe readmission patterns after robotic surgery for endometrial cancer and identify risk factors for readmission within 90 days of…”
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Safe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogs by Rath, Kellie S, McCann, Georgia A, Cohn, David E, Rivera, Brian K, Kuppusamy, Periannan, Selvendiran, Karuppaiyah

“…A diagnosis of advanced ovarian cancer is the beginning of a long and arduous journey for a patient. Worldwide, approximately half of the individuals…”
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Reply by Rath, Kellie S., Fowler, Jeffery M.

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Outcomes of the BRCA quality improvement dissemination program in three health systems by Bednar, Erica M., Chen, Minxing, Walsh, Michael T., Eppolito, Amanda L., Teed, Kelly B., Klein, Molly H., Chao, Han, Berg, Jordan, Bowman, Erin, Yobbi, Cara S., Krukenberg, Rebekah C., Jenkinson, Sandra, Moore, Jennifer, Garcia, Cassie, Goedde, Timothy, Morman, Nichole A., Bowdish, Elizabeth C., Wise, Emaline, Rath, Kellie S., Lu, Karen H.

“…10603 Background: The BRCA Quality Improvement Dissemination Program (BQIDP) was disseminated to 3 community-based health systems’ oncology clinics in 2017…”
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Reply by Rath, Kellie S., MD, Fowler, Jeffery M., MD

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Abstract POSTER-THER-1413: Targeting constitutively-activated STAT3 in hypoxic ovarian cancer by McCann, Georgia A, ElNaggar, Adam, Naidu, Shan, Rath, Kellie S, Tierney, Brent J, Suarez, Adrian, Cohn, David E, Selvendiran, Karuppaiyah

“…Abstract Background: Tumor hypoxia, a feature of many solid tumors including ovarian cancer, is associated with resistance to therapies. We previously…”
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Reply by Rath, Kellie S, Fowler, Jeffery M

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Reply by Rath, Kellie S, Fowler, Jeffery M

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Abstract LB-28: Suppression of ovarian tumor growth and metastasis with a STAT3 inhibitor, HO-3867, in preclinical orthotopic models and ex vivo cultures of ovarian cancer by Naidu, Shan K., Saini, Uksha, ElNaggar, Adam C., Hemant, Bid K., Rath, Kellie S., Wanner, Ross, Suarez, Adrian, Hays, John, Houghton, Peter, Cohn, David E., Selvendiran, Karuppaiyah

“…Abstract Objective: We previously studied a novel anticancer compound, HO-3867, in in vitro culture and xenograft ovarian tumor models. In our current study,…”
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Doxorubicin synergizes with 34.5 ENVE to enhance antitumor efficacy against metastatic ovarian cancer by Bolyard, Chelsea, Yoo, Ji Young, Wang, Pin-Yi, Saini, Uksha, Rath, Kellie S., Cripe, Tim, Zhang, Jianying, Selvendiran, Karuppaiyah, Kaur, Balveen

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