Search Results - "Rataud, J"

Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils by Malgouris, C, Bardot, F, Daniel, M, Pellis, F, Rataud, J, Uzan, A, Blanchard, JC, Laduron, PM

“…The neuroprotective effects of riluzole, a novel antiglutamate, has been demonstrated in a model of ischemia induced in female Mongolian gerbils by transient…”
Get full text

Are 5-HT2 antagonists endowed with anxiolytic properties in rodents? by Stutzmann, J M, Eon, B, Darche, F, Lucas, M, Rataud, J, Piot, O, Blanchard, J C, Laduron, P M

“…The precise role of serotonin (5-HT) in anxiety remains unclear. We report here on the effects of RP 62203, a new 5-HT2 antagonist, and ritanserin in different…”
Get more information

Ion source developments for RNB production at SPIRAL/GANIL by Villari, A.C.C., Barué, C., Gaubert, G., Gibouin, S., Huguet, Y., Jardin, P., Kandri-Rody, S., Landré-Pellemoine, F., Lecesne, N., Leroy, R., Lewitowicz, M., Marry, C., Maunoury, L., Pacquet, J.Y., Rataud, J.P., Saint-Laurent, M.G., Stodel, C., Angélique, J.C., Orr, N.A., Lichtenthäler, R.

“…The first on-line production system for SPIRAL/GANIL (Radioactive Ion Production System with Acceleration on-Line) phase-I has been commissioned on the SIRa…”
Get full text

Recent results at the SIRa test bench: Diffusion properties of carbon graphite and B4C targets by Landré-Pellemoine, F., Angelique, J.C., Bajeat, O., Barué, C., Bennett, R., Clapier, F., Ducourtieux, M., Gaubert, G., Gibouin, S., Huguet, Y., Jardin, P., Kandri-Rody, S., Lau, C., Lecesne, N., Leroy, R., Lewitowicz, M., Lichtenthäler, R., Marry, C., Maunoury, L., Obert, J., Orr, N.A., Pacquet, J.Y., Saint-Laurent, M.G., Stodel, C., Rataud, J.P., Villari, A.C.C.

Get full text

Effects of riluzole on the evolution of focal cerebral ischemia: a magnetic resonance imaging study by Mottet, I, Demeure, R, Rataud, J, Lucas, M, Wahl, F, Warscotte, V, Thiran, J P, Goudemant, J F, Maldague, B, Maloteaux, J M, Stutzmann, J M

“…The aim of this study was to investigate the effects of riluzole on the lesion induced by a permanent middle cerebral artery occlusion (MCAO) in rats. Riluzole…”
Get full text

RP 59037 and RP 60503: anxiolytic cyclopyrrolone derivatives with low sedative potential. interaction with the gamma-aminobutyric acidA/benzodiazepine receptor complex and behavioral effects in the rodent by Doble, A, Canton, T, Dreisler, S, Piot, O, Boireau, A, Stutzmann, J M, Bardone, M C, Rataud, J, Roux, M, Roussel, G

“…This study describes the pharmacological properties of two novel cyclopyrrolone derivatives, RP 59037 [2-(7-chloro-2-naphthyridin-1,8-yl)-3-(5-…”
Get more information

Riluzole Series. Synthesis and in Vivo “Antiglutamate” Activity of 6-Substituted-2-benzothiazolamines and 3-Substituted-2-imino-benzothiazolines by Jimonet, Patrick, Audiau, François, Barreau, Michel, Blanchard, Jean-Charles, Boireau, Alain, Bour, Yvette, Coléno, Marie-Annick, Doble, Adam, Doerflinger, Gilles, Do Huu, Claudine, Donat, Marie-Hélène, Duchesne, Jean Marie, Ganil, Pierre, Guérémy, Claude, Honoré, Eliane, Just, Bernard, Kerphirique, Roselyne, Gontier, Sylvie, Hubert, Philippe, Laduron, Pierre M, Le Blevec, Joseph, Meunier, Mireille, Miquet, Jean-Marie, Nemecek, Conception, Pasquet, Martine, Piot, Odile, Pratt, Jeremy, Rataud, Jean, Reibaud, Michel, Stutzmann, Jean-Marie, Mignani, Serge

“…Two series of analogues of riluzole, a blocker of excitatory amino acid mediated neurotransmission, have been synthesized: monosubstituted 2-benzothiazolamines…”
Get full text

Pharmacological evidence of a possible tryptaminergic regulation of opiate receptors by using indalpine, a selective 5-HT uptake inhibitor by Uzan, A, Kabouche, M, Rataud, J, Le Fur, G

Get more information

On the long acting gastric antisecretory activity of LM 24056 a non H2 antagonist by Mizoule, J, Rataud, J, Le Fur, G, Jozefczak, C, Quarteronet, D, Uzan, A

“…LM 24056, a phenothiazine derivative with no central effects, can be classified as a non anti H2 antisecretory agent with a long duration of action. Its…”
Get more information

Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents by Rataud, J, Debarnot, F, Mary, V, Pratt, J, Stutzmann, J M

“…This study evaluates the neuroprotective properties of some voltage-sensitive sodium channel blockers in a model of focal ischaemia. After curative treatment…”
Get more information

New Beam Diagnostics at GANIL : Very Sensitive Current Transformers in Beam Lines and Counting System of Beam Turns in Cyclotrons by Loyer, F., Andre, T., Ducoudret, B., Rataud, J. P.

“…Two new beam diagnostics have been designed and are in operation at GANIL : - To measure very small beam currents without intercepting the beam, transformers…”
Get full text

Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia by Pratt, J, Rataud, J, Bardot, F, Roux, M, Blanchard, J C, Laduron, P M, Stutzmann, J M

“…Riluzole (2 amino 6-trifluoromethoxybenzothiazole), when administered at 4 and 8 mg/kg i.p., 0.5, 4.5, 24 and 28 h after the initiation of ischaemia,…”
Get more information

Pharmacological evidence that PK 8165 behaves as a partial agonist of brain type benzodiazepine receptors by Mizoule, J, Rataud, J, Uzan, A, Mazadier, M, Daniel, M, Gauthier, A, Ollat, C, Gueremy, C, Renault, C, Dubroeucq, M C

“…PK 8165, a new quinoline derivative, has a good affinity for brain type benzodiazepine binding sites and an anticonflict activity in the Vogel Test. However,…”
Get more information

The effect of riluzole and mannitol on cerebral oedema after cryogenic injury in the mouse by Pratt, Jeremy, Archambaud, Christelle, Böhme, G.Andrees, Roux, Michel, Rataud, Jean, Imperato, Assunta, Stutzmann, Jean-Marie

“…A cryogenic lesion was produced under halothane anaesthesia in the mouse by placing a cotton swab soaked in liquid nitrogen onto the surface of the cranium…”
Get full text

'Anxiolytic' effect of CCK-antagonists on plus-maze behavior in mice by Rataud, J, Darche, F, Piot, O, Stutzmann, J M, Böhme, G A, Blanchard, J C

“…The effects of systemic treatment with the CCK-B receptor antagonist L-365,260, its 3S-(-) enantiomer and the CCK-A receptor antagonist devazepide were…”
Get more information

Synthesis, anticonvulsant and neuroprotective activities of RP 66055, a riluzole derivative by Jimonet, P, Barreau, M, Blanchard, J C, Boireau, A, Doble, A, Laduron, P, Lavayre, J, Malgouris, C, Piot, O, Pratt, J

Get more information

New beam diagnostics at GANIL: Very sensitive transformers in beam lines and counting system of beam turns in cyclotrons by Loyer, F, Andre, T, Ducoudret, B, Rataud, J P

“…To measure very small beam currents without intercepting the beam, transformers have been developed whose resolution is as low as 1 enA. That is obtained by…”
Get full text

Mezilamine, a new dopamine antagonist, blocks presynaptic but stimulates postsynaptic alpha-adrenoceptors by Le Fur, G, Mizoule, J, Rataud, J, Uzan, A

Get more information

3-(4-Piperidinylalkyl)indoles, selective inhibitors of neuronal 5-hydroxytryptamine uptake by Gueremy, Claude, Audiau, Francois, Champseix, Alain, Uzan, Andre, Le Fur, Gerard, Rataud, Jean

“…A series of 3-(4-piperidinylalkyl)indoles was synthesized and tested as uptake inhibitors of biogenic amines. Some of these compounds are potent and very…”
Get full text

Neuroprotection against ischaemia and Improvement of sleep quality with rlluzole a novel antiglutamate by Blanchard, J.C., Malgouris, C., Rataud, J., Stutzmann, J.M., Laduron, P.M.

Get full text