Search Results - "Rasul, Azhar"

Biochanin A: A novel bioactive multifunctional compound from nature by Sarfraz, Ayesha, Javeed, Maria, Shah, Muhammad Ajmal, Hussain, Ghulam, Shafiq, Nusrat, Sarfraz, Iqra, Riaz, Ammara, Sadiqa, Ayesha, Zara, Rabia, Zafar, Saba, Kanwal, Lubna, Sarker, Satyajit D., Rasul, Azhar

“…Natural products (NPs) will continue to serve humans as matchless source of novel drug leads and an inspiration for the synthesis of non-natural drugs. As our…”
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Current Status of Therapeutic Approaches against Peripheral Nerve Injuries: A Detailed Story from Injury to Recovery by Hussain, Ghulam, Wang, Jing, Rasul, Azhar, Anwar, Haseeb, Qasim, Muhammad, Zafar, Shamaila, Aziz, Nimra, Razzaq, Aroona, Hussain, Rashad, de Aguilar, Jose-Luis Gonzalez, Sun, Tao

“…Peripheral nerve injury is a complex condition with a variety of signs and symptoms such as numbness, tingling, jabbing, throbbing, burning or sharp pain…”
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Role of cholesterol and sphingolipids in brain development and neurological diseases by Hussain, Ghulam, Wang, Jing, Rasul, Azhar, Anwar, Haseeb, Imran, Ali, Qasim, Muhammad, Zafar, Shamaila, Kamran, Syed Kashif Shahid, Razzaq, Aroona, Aziz, Nimra, Ahmad, Waseem, Shabbir, Asghar, Iqbal, Javed, Baig, Shahid Mahmood, Sun, Tao

“…Brain is a vital organ of the human body which performs very important functions such as analysis, processing, coordination, and execution of electrical…”
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Repositioning of acefylline as anti-cancer drug: Synthesis, anticancer and computational studies of azomethines derived from acefylline tethered 4-amino-3-mercapto-1,2,4-triazole by Shahzadi, Irum, Zahoor, Ameer Fawad, Tüzün, Burak, Mansha, Asim, Anjum, Muhammad Naveed, Rasul, Azhar, Irfan, Ali, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…Novel azomethines derived from acefylline tethered triazole hybrids (7a-k) have been synthesized and evaluated against human liver cancer cell line (Hep G2)…”
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Identification of Novel Natural Inhibitors to Human 3-Phosphoglycerate Dehydrogenase (PHGDH) for Cancer Treatment by Sadiqa, Ayesha, Rasul, Azhar, Hassan, Mudassir, Sultana, Salma, Jabeen, Farhat

“…Targeting the serine biosynthesis pathway enzymes has turned up as a novel strategy for anti-cancer therapeutics. 3- Phosphoglycerate dehydrogenase (PHGDH) is…”
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PIAS family in cancer: from basic mechanisms to clinical applications by Li, Xiaomeng, Rasul, Azhar, Sharif, Farzana, Hassan, Mudassir

“…Protein inhibitors of activated STATs (PIAS) are proteins for cytokine signaling that activate activator-mediated gene transcription. These proteins, as…”
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Role of Plant-Derived Flavonoids and Their Mechanism in Attenuation of Alzheimer's and Parkinson's Diseases: An Update of Recent Data by Hussain, Ghulam, Zhang, Longbin, Rasul, Azhar, Anwar, Haseeb, Sohail, Muhammad Umar, Razzaq, Aroona, Aziz, Nimra, Shabbir, Asghar, Ali, Muhammad, Sun, Tao

“…Neurodegeneration is a progressive loss of neuronal cells in certain regions of the brain. Most of the neurodegenerative disorders (NDDs) share the communal…”
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Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities by Riaz, Ammara, Rasul, Azhar, Hussain, Ghulam, Zahoor, Muhammad Kashif, Jabeen, Farhat, Subhani, Zinayyera, Younis, Tahira, Ali, Muhammad, Sarfraz, Iqra, Selamoglu, Zeliha

“…Natural products, an infinite treasure of bioactive chemical entities, persist as an inexhaustible resource for discovery of drugs. This review article intends…”
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Identification of Natural Compounds as Inhibitors of Pyruvate Kinase M2 for Cancer Treatment by Sarfraz, Iqra, Rasul, Azhar, Jabeen, Farhat, Sultana, Tayyaba, Adem, Şevki

“…The reliance of tumor cells on aerobic glycolysis is one of the emerging hallmarks of cancer. Pyruvate kinase M2 (PKM2), an important enzyme of glycolytic…”
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Putative Roles of Plant-Derived Tannins in Neurodegenerative and Neuropsychiatry Disorders: An Updated Review by Hussain, Ghulam, Huang, Jia, Rasul, Azhar, Anwar, Haseeb, Imran, Ali, Maqbool, Javeria, Razzaq, Aroona, Aziz, Nimra, Makhdoom, Ehtisham Ul Haq, Konuk, Muhsin, Sun, Tao

“…Neurodegenerative and neuropsychiatric diseases are characterized by the structural and functional abnormalities of neurons in certain regions of the brain…”
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Exploring the Synergistic Anticancer Potential of Benzofuran-Oxadiazoles and Triazoles: Improved Ultrasound- and Microwave-Assisted Synthesis, Molecular Docking, Hemolytic, Thrombolytic and Anticancer Evaluation of Furan-Based Molecules by Irfan, Ali, Faiz, Sadia, Rasul, Azhar, Zafar, Rehman, Zahoor, Ameer Fawad, Kotwica-Mojzych, Katarzyna, Mojzych, Mariusz

“…Ultrasound- and microwave-assisted green synthetic strategies were applied to furnish benzofuran-oxadiazole - and benzofuran-triazole - derivatives in good to…”
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Cost-effective fabrication, antibacterial application and cell viability studies of modified nonwoven cotton fabric by Nawaz, Rahat, Naqvi, Sayed Tayyab Raza, Fatima, Batool, Zulfiqar, Nazia, Farooq, Muhammad Umer, Haq, Muhammad Najam ul, Hussain, Dilshad, Javeed, Asghar, Rasul, Azhar, Jafri, Laila, Majeed, Saadat, Khan, Waheed Qamar

“…In the present work, nonwoven cotton fabric was modified for antibacterial applications using low-cost and eco-friendly precursors. The treatment of fabric…”
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Osthole: A Multifunctional Natural Compound with Potential Anticancer, Antioxidant and Anti-inflammatory Activities by Zafar, Saba, Sarfraz, Iqra, Rasul, Azhar, Shah, Muhammad Ajmal, Hussain, Ghulam, Zahoor, Muhammad Kashif, Shafiq, Nusrat, Riaz, Ammara, Selamoglu, Zeliha, Sarker, Satyajit D

“…Nature has always proved to be a significant reservoir of bioactive scaffolds that have been used for the discovery of drugs since times. Medicinal plants…”
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Induction of apoptosis by costunolide in bladder cancer cells is mediated through ROS generation and mitochondrial dysfunction by Rasul, Azhar, Bao, Rui, Malhi, Mahadev, Zhao, Bing, Tsuji, Ichiro, Li, Jiang, Li, Xiaomeng

“…Despite the availability of several therapeutic options, a safer and more effective modality is urgently needed for treatment of bladder cancer. Costunolide, a…”
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Bombax ceiba extract and its metabolites as α-glucosidase inhibitors for diabetes by Hassan, Mudassir, Rasul, Azhar, Jabeen, Farhat, Sultana, Salma, Manan, Maria

“…Alpha-glucosidase inhibitors characterize a major class of Type II antidiabetic drugs and play a significant role in lowering postprandial hyperglycemia…”
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Dissecting the Role of SMYD2 and Its Inhibitor (LLY-507) in the Treatment of Chemically Induced Non-Small Cell Lung Cancer (NSCLC) by Using Fe3O4 Nanoparticles Drug Delivery System by Munawwar, Aasma, Sajjad, Amna, Rasul, Azhar, Sattar, Mehran, Jabeen, Farhat

“…Cancer therapies based on nanoparticles with a loaded drug can overcome the problem of the drug’s toxic effects in the traditional chemotherapeutic approach…”
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Non-genetic heterogeneity and immune subtyping in breast cancer: Implications for immunotherapy and targeted therapeutics by Hassan, Mudassir, Tutar, Lütfi, Sari-Ak, Duygu, Rasul, Azhar, Basheer, Ejaz, Tutar, Yusuf

“…•Non-genetic factors shape cancer evolution and influence therapeutic outcomes.•Non-genetic heterogeneity diverse subpopulations of cancer cells within breast…”
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Chalepin and Chalepensin: Occurrence, Biosynthesis and Therapeutic Potential by Nahar, Lutfun, Al-Majmaie, Shaymaa, Al-Groshi, Afaf, Rasul, Azhar, Sarker, Satyajit D

“…Dihydrofuranocoumarin, chalepin ( ) and furanocoumarin, chalepensin ( ) are 3-prenylated bioactive coumarins, first isolated from the well-known medicinal…”
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Jaceosidin: A Natural Flavone with Versatile Pharmacological and Biological Activities by Nageen, Bushra, Rasul, Azhar, Hussain, Ghulam, Shah, Muhammad A, Anwar, Haseeb, Hussain, Syed M, Uddin, Md Sahab, Sarfraz, Iqra, Riaz, Ammara, Selamoglu, Zeliha

“…Nature always remains an inexhaustible source of treasures for mankind. It remains a mystery for every challenge until the completion of the challenge. While…”
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Synthesis, Hemolytic Studies, and In Silico Modeling of Novel Acefylline–1,2,4-Triazole Hybrids as Potential Anti-cancer Agents against MCF‑7 and A549 by Shahzadi, Irum, Zahoor, Ameer Fawad, Rasul, Azhar, Mansha, Asim, Ahmad, Sajjad, Raza, Zohaib

“…A series of novel theophylline-7-acetic acid (acefylline)-derived 1,2,4-triazole hybrids with N-phenyl acetamide moieties (11a–j) have been synthesized and…”
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