Search Results - "Rastelli, Francesca"

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program by Verzoni, Elena, Cartenì, Giacomo, Cortesi, Enrico, Giannarelli, Diana, De Giglio, Andrea, Sabbatini, Roberto, Buti, Sebastiano, Rossetti, Sabrina, Cognetti, Francesco, Rastelli, Francesca, Sobrero, Alberto, Turci, Daniele, Sternberg, Cora N, Porta, Camillo, Cappuzzo, Federico, Tortora, Giampaolo, Tassinari, Davide, Panni, Stefano, Pazzola, Antonio, Surico, Gianmarco, Raimondi, Alessandra, De Giorgi, Ugo, Procopio, Giuseppe

“…The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal…”
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Factors predictive of response to hormone therapy in breast cancer by Rastelli, Francesca, Crispino, Sergio

“…Approximately half of metastatic breast cancers expressing estrogen and/or progesterone receptors responds to endocrine therapy, and postoperative adjuvant…”
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Early fatigue in cancer patients receiving PD-1/PD-L1 checkpoint inhibitors: an insight from clinical practice by Cortellini, Alessio, Vitale, Maria G, De Galitiis, Federica, Di Pietro, Francesca R, Berardi, Rossana, Torniai, Mariangela, De Tursi, Michele, Grassadonia, Antonino, Di Marino, Pietro, Santini, Daniele, Zeppola, Tea, Anesi, Cecilia, Gelibter, Alain, Occhipinti, Mario Alberto, Botticelli, Andrea, Marchetti, Paolo, Rastelli, Francesca, Pergolesi, Federica, Tudini, Marianna, Silva, Rosa Rita, Mallardo, Domenico, Vanella, Vito, Ficorella, Corrado, Porzio, Giampiero, Ascierto, Paolo A

“…Fatigue was reported as the most common any-grade adverse event (18.3%), and the most common grade 3 or higher immune-related adverse event (irAE) (0.89%) in…”
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The Remapping of Peripersonal Space in a Real but Not in a Virtual Environment by Ferroni, Francesca, Gallese, Vittorio, Soccini, Agata Marta, Langiulli, Nunzio, Rastelli, Francesca, Ferri, Donato, Bianchi, Francesco, Ardizzi, Martina

“…One of the most surprising features of our brain is the fact that it is extremely plastic. Among the various plastic processes supported by our brain, there is…”
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Host immune‐inflammatory markers to unravel the heterogeneous outcome and assessment of patients with PD‐L1 ≥50% metastatic non‐small cell lung cancer and poor performance status receiving first‐line immunotherapy by Banna, Giuseppe L., Tiseo, Marcello, Cortinovis, Diego L., Facchinetti, Francesco, Aerts, Joachim G. J. V., Baldessari, Cinzia, Giusti, Raffaele, Bria, Emilio, Grossi, Francesco, Berardi, Rossana, Morabito, Alessandro, Catino, Annamaria, Genova, Carlo, Mazzoni, Francesca, Gelibter, Alain, Rastelli, Francesca, Macerelli, Marianna, Chiari, Rita, Gori, Stefania, Mansueto, Giovanni, Citarella, Fabrizio, Cantini, Luca, Rijavec, Erika, Bertolini, Federica, Cappuzzo, Federico, De Toma, Alessandro, Friedlaender, Alex, Metro, Giulio, Pensieri, Maria Vittoria, Porzio, Giampiero, Ficorella, Corrado, Pinato, David J., Cortellini, Alessio, Addeo, Alfredo

“…Background Patients with programmed cell death‐ligand 1 (PD‐L1) ≥50% metastatic non‐small cell lung cancer (mNSCLC) and ECOG performance status (PS) of 2…”
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Safety and efficacy of nivolumab for metastatic renal cell carcinoma (mRCC): Real world data from an Italian expanded access program (EAP) by De Giorgi, Ugo, Scagliarini, Sarah, Basso, Umberto, Galli, Luca, Mosillo, Claudia, Caserta, Claudia, Rossetti, Sabrina, Guida, Annalisa, Bearz, Alessandra, Buti, Sebastiano, Lo Re, Giovanni, Valcamonico, Francesca, Hamzaj, Alketa, Cognetti, Francesco, Rastelli, Francesca, Fornarini, Giuseppe, Porta, Camillo, Del Bene, Gabriella, Turci, Daniele, Procopio, Giuseppe

“…Abstract only 4577 Background: Nivolumab showed a survival benefit in a randomised phase III trial in pre-treated mRCC. The EAP provided the opportunity to…”
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Biallelic variants in TAMM41 are associated with low muscle cardiolipin levels, leading to neonatal mitochondrial disease by Thompson, Kyle, Bianchi, Lucas, Rastelli, Francesca, Piron-Prunier, Florence, Ayciriex, Sophie, Besmond, Claude, Hubert, Laurence, Barth, Magalie, Barbosa, Inês A., Deshpande, Charu, Chitre, Manali, Mehta, Sarju G., Wever, Eric J.M., Marcorelles, Pascale, Donkervoort, Sandra, Saade, Dimah, Bönnemann, Carsten G., Chao, Katherine R., Cai, Chunyu, Iannaccone, Susan T., Dean, Andrew F., McFarland, Robert, Vaz, Frédéric M., Delahodde, Agnès, Taylor, Robert W., Rötig, Agnès

“…Mitochondrial disorders are clinically and genetically heterogeneous, with variants in mitochondrial or nuclear genes leading to varied clinical phenotypes…”
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Tool-use Extends Peripersonal Space Boundaries in Schizophrenic Patients by Ferroni, Francesca, Ardizzi, Martina, Magnani, Francesca, Ferri, Francesca, Langiulli, Nunzio, Rastelli, Francesca, Lucarini, Valeria, Giustozzi, Francesca, Volpe, Roberto, Marchesi, Carlo, Tonna, Matteo, Gallese, Vittorio

“…Abstract Background and Hypothesis A primary disruption of the bodily self is considered a core feature of schizophrenia (SCZ). The “disembodied” self might be…”
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Effect of concomitant medications with immune-modulatory properties on the outcomes of patients with advanced cancer treated with immune checkpoint inhibitors: development and validation of a novel prognostic index by Buti, Sebastiano, Bersanelli, Melissa, Perrone, Fabiana, Tiseo, Marcello, Tucci, Marco, Adamo, Vincenzo, Stucci, Luigia S., Russo, Alessandro, Tanda, Enrica T., Spagnolo, Francesco, Rastelli, Francesca, Pergolesi, Federica, Santini, Daniele, Russano, Marco, Anesi, Cecilia, Giusti, Raffaele, Filetti, Marco, Marchetti, Paolo, Botticelli, Andrea, Gelibter, Alain, Occhipinti, Mario Alberto, Ferrari, Marco, Vitale, Maria Giuseppa, Nicolardi, Linda, Chiari, Rita, Rijavec, Erika, Nigro, Olga, Tuzi, Alessandro, De Tursi, Michele, Di Marino, Pietro, Conforti, Fabio, Queirolo, Paola, Bracarda, Sergio, Macrini, Serena, Gori, Stefania, Zoratto, Federica, Veltri, Enzo, Di Cocco, Barbara, Mallardo, Domenico, Vitale, Maria Grazia, Santoni, Matteo, Patruno, Leonardo, Porzio, Giampiero, Ficorella, Corrado, Pinato, David J., Ascierto, Paolo A., Cortellini, Alessio

“…Concomitant medications are known to impact on clinical outcomes of patients treated with immune checkpoint inhibitors (ICIs). We aimed weighing the role of…”
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Another side of the association between body mass index (BMI) and clinical outcomes of cancer patients receiving programmed cell death protein-1 (PD-1)/ Programmed cell death-ligand 1 (PD-L1) checkpoint inhibitors: A multicentre analysis of immune-related adverse events by Cortellini, Alessio, Bersanelli, Melissa, Santini, Daniele, Buti, Sebastiano, Tiseo, Marcello, Cannita, Katia, Perrone, Fabiana, Giusti, Raffaele, De Tursi, Michele, Zoratto, Federica, Marconcini, Riccardo, Russano, Marco, Zeppola, Tea, Anesi, Cecilia, Filetti, Marco, Marchetti, Paolo, Botticelli, Andrea, Gelibter, Alain, De Galitiis, Federica, Vitale, Maria Giuseppa, Rastelli, Francesca, Tudini, Marianna, Silva, Rosa Rita, Atzori, Francesco, Chiari, Rita, Ricciuti, Biagio, De Giglio, Andrea, Migliorino, Maria Rita, Mallardo, Domenico, Vanella, Vito, Mosillo, Claudia, Bracarda, Sergio, Rinaldi, Silvia, Berardi, Rossana, Natoli, Clara, Ficorella, Corrado, Porzio, Giampiero, Ascierto, Paolo A.

“…Several studies have found an association between higher body mass index (BMI) and improved clinical outcomes in cancer patients receiving programmed cell…”
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A multicenter study of body mass index in cancer patients treated with anti-PD-1/PD-L1 immune checkpoint inhibitors: when overweight becomes favorable by Cortellini, Alessio, Bersanelli, Melissa, Buti, Sebastiano, Cannita, Katia, Santini, Daniele, Perrone, Fabiana, Giusti, Raffaele, Tiseo, Marcello, Michiara, Maria, Di Marino, Pietro, Tinari, Nicola, De Tursi, Michele, Zoratto, Federica, Veltri, Enzo, Marconcini, Riccardo, Malorgio, Francesco, Russano, Marco, Anesi, Cecilia, Zeppola, Tea, Filetti, Marco, Marchetti, Paolo, Botticelli, Andrea, Antonini Cappellini, Gian Carlo, De Galitiis, Federica, Vitale, Maria Giuseppa, Rastelli, Francesca, Pergolesi, Federica, Berardi, Rossana, Rinaldi, Silvia, Tudini, Marianna, Silva, Rosa Rita, Pireddu, Annagrazia, Atzori, Francesco, Chiari, Rita, Ricciuti, Biagio, De Giglio, Andrea, Iacono, Daniela, Gelibter, Alain, Occhipinti, Mario Alberto, Parisi, Alessandro, Porzio, Giampiero, Fargnoli, Maria Concetta, Ascierto, Paolo Antonio, Ficorella, Corrado, Natoli, Clara

“…Recent evidence suggested a potential correlation between overweight and the efficacy of immune checkpoint inhibitors (ICIs) in cancer patients. We conducted a…”
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Clinicopathologic correlates of first-line pembrolizumab effectiveness in patients with advanced NSCLC and a PD-L1 expression of ≥ 50 by Cortellini, Alessio, Tiseo, Marcello, Banna, Giuseppe L., Cappuzzo, Federico, Aerts, Joachim G. J. V., Barbieri, Fausto, Giusti, Raffaele, Bria, Emilio, Cortinovis, Diego, Grossi, Francesco, Migliorino, Maria R., Galetta, Domenico, Passiglia, Francesco, Santini, Daniele, Berardi, Rossana, Morabito, Alessandro, Genova, Carlo, Mazzoni, Francesca, Di Noia, Vincenzo, Signorelli, Diego, Tuzi, Alessandro, Gelibter, Alain, Marchetti, Paolo, Macerelli, Marianna, Rastelli, Francesca, Chiari, Rita, Rocco, Danilo, Gori, Stefania, De Tursi, Michele, Mansueto, Giovanni, Zoratto, Federica, Santoni, Matteo, Tudini, Marianna, Rijavec, Erika, Filetti, Marco, Catino, Annamaria, Pizzutilo, Pamela, Sala, Luca, Citarella, Fabrizio, Marco, Russano, Torniai, Mariangela, Cantini, Luca, Targato, Giada, Sforza, Vincenzo, Nigro, Olga, Ferrara, Miriam G., D’Argento, Ettore, Buti, Sebastiano, Bordi, Paola, Antonuzzo, Lorenzo, Scodes, Simona, Landi, Lorenza, Guaitoli, Giorgia, Baldessari, Cinzia, Della Gravara, Luigi, Dal Bello, Maria Giovanna, Belderbos, Robert A., Bironzo, Paolo, Carnio, Simona, Ricciardi, Serena, Grieco, Alessio, De Toma, Alessandro, Proto, Claudia, Friedlaender, Alex, Cantale, Ornella, Ricciuti, Biagio, Addeo, Alfredo, Metro, Giulio, Ficorella, Corrado, Porzio, Giampiero

“…Background Single-agent pembrolizumab represents the standard first-line option for metastatic non-small-cell lung cancer (NSCLC) patients with a PD-L1…”
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Integrated analysis of concomitant medications and oncological outcomes from PD-1/PD-L1 checkpoint inhibitors in clinical practice by Cortellini, Alessio, Tucci, Marco, Adamo, Vincenzo, Stucci, Luigia Stefania, Russo, Alessandro, Tanda, Enrica Teresa, Spagnolo, Francesco, Rastelli, Francesca, Bisonni, Renato, Santini, Daniele, Russano, Marco, Anesi, Cecilia, Giusti, Raffaele, Filetti, Marco, Marchetti, Paolo, Botticelli, Andrea, Gelibter, Alain, Occhipinti, Mario Alberto, Marconcini, Riccardo, Vitale, Maria Giuseppa, Nicolardi, Linda, Chiari, Rita, Bareggi, Claudia, Nigro, Olga, Tuzi, Alessandro, De Tursi, Michele, Petragnani, Nicola, Pala, Laura, Bracarda, Sergio, Macrini, Serena, Inno, Alessandro, Zoratto, Federica, Veltri, Enzo, Di Cocco, Barbara, Mallardo, Domenico, Vitale, Maria Grazia, Pinato, David James, Porzio, Giampiero, Ficorella, Corrado, Ascierto, Paolo Antonio

“…BackgroundConcomitant medications, such as steroids, proton pump inhibitors (PPI) and antibiotics, might affect clinical outcomes with immune checkpoint…”
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Type 2 Diabetes Mellitus and Efficacy Outcomes from Immune Checkpoint Blockade in Patients with Cancer by Cortellini, Alessio, D'Alessio, Antonio, Cleary, Siobhan, Buti, Sebastiano, Bersanelli, Melissa, Bordi, Paola, Tonini, Giuseppe, Vincenzi, Bruno, Tucci, Marco, Russo, Alessandro, Pantano, Francesco, Russano, Marco, Stucci, Luigia Stefania, Sergi, Maria Chiara, Falconi, Martina, Zarzana, Maria Antonietta, Santini, Daniele, Spagnolo, Francesco, Tanda, Enrica T, Rastelli, Francesca, Giorgi, Francesca Chiara, Pergolesi, Federica, Giusti, Raffaele, Filetti, Marco, Lo Bianco, Francesca, Marchetti, Paolo, Botticelli, Andrea, Gelibter, Alain, Siringo, Marco, Ferrari, Marco, Marconcini, Riccardo, Vitale, Maria Giuseppa, Nicolardi, Linda, Chiari, Rita, Ghidini, Michele, Nigro, Olga, Grossi, Francesco, De Tursi, Michele, Di Marino, Pietro, Queirolo, Paola, Bracarda, Sergio, Macrini, Serena, Inno, Alessandro, Zoratto, Federica, Veltri, Enzo, Spoto, Chiara, Vitale, Maria Grazia, Cannita, Katia, Gennari, Alessandra, Morganstein, Daniel L, Mallardo, Domenico, Nibid, Lorenzo, Sabarese, Giovanna, Brunetti, Leonardo, Perrone, Giuseppe, Ascierto, Paolo A, Ficorella, Corrado, Pinato, David J

“…No evidence exists as to whether type 2 diabetes mellitus (T2DM) impairs clinical outcome from immune checkpoint inhibitors (ICI) in patients with solid…”
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Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line pembrolizumab versus cytotoxic chemotherapy by Cortellini, Alessio, Di Maio, Massimo, Nigro, Olga, Leonetti, Alessandro, Cortinovis, Diego L, Aerts, Joachim GJV, Guaitoli, Giorgia, Barbieri, Fausto, Giusti, Raffaele, Ferrara, Miriam G, Bria, Emilio, D'Argento, Ettore, Grossi, Francesco, Rijavec, Erika, Guida, Annalisa, Berardi, Rossana, Torniai, Mariangela, Sforza, Vincenzo, Genova, Carlo, Mazzoni, Francesca, Garassino, Marina Chiara, De Toma, Alessandro, Signorelli, Diego, Gelibter, Alain, Siringo, Marco, Marchetti, Paolo, Macerelli, Marianna, Rastelli, Francesca, Chiari, Rita, Rocco, Danilo, Della Gravara, Luigi, Inno, Alessandro, Michele, De Tursi, Grassadonia, Antonino, Di Marino, Pietro, Mansueto, Giovanni, Zoratto, Federica, Filetti, Marco, Santini, Daniele, Citarella, Fabrizio, Russano, Marco, Cantini, Luca, Tuzi, Alessandro, Bordi, Paola, Minuti, Gabriele, Landi, Lorenza, Ricciardi, Serena, Migliorino, Maria R, Passiglia, Francesco, Bironzo, Paolo, Metro, Giulio, Adamo, Vincenzo, Russo, Alessandro, Spinelli, Gian Paolo, Banna, Giuseppe L, Friedlaender, Alex, Addeo, Alfredo, Cannita, Katia, Ficorella, Corrado, Porzio, Giampiero, Pinato, David J

“…BackgroundSome concomitant medications including antibiotics (ATB) have been reproducibly associated with worse survival following immune checkpoint inhibitors…”
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Real-world outcomes of Italian patients with advanced non-squamous lung cancer treated with first-line pembrolizumab plus platinum-pemetrexed by Leonetti, Alessandro, Perrone, Fabiana, Puntoni, Matteo, Maglietta, Giuseppe, Bordi, Paola, Bria, Emilio, Vita, Emanuele, Gelsomino, Francesco, De Giglio, Andrea, Gelibter, Alain, Siringo, Marco, Mazzoni, Francesca, Caliman, Enrico, Genova, Carlo, Bertolini, Federica, Guaitoli, Giorgia, Passiglia, Francesco, Delcuratolo, Marco Donatello, Montrone, Michele, Cerea, Giulio, Pasello, Giulia, Roca, Elisa, Belluomini, Lorenzo, Cecere, Fabiana Letizia, Guida, Annalisa, Manzo, Anna, Adamo, Vincenzo, Rastelli, Francesca, Bulotta, Alessandra, Citarella, Fabrizio, Toschi, Luca, Zoratto, Federica, Cortinovis, Diego Luigi, Berardi, Rossana, Follador, Alessandro, Carta, Annamaria, Camerini, Andrea, Salerno, Flavio, Silva, Rosa Rita, Baldini, Editta, Cortellini, Alessio, Brighenti, Matteo, Santoni, Matteo, Malorgio, Francesco, Caminiti, Caterina, Tiseo, Marcello

“…The aim of this multi-center, retrospective/prospective cohort observational study was to evaluate outcomes in routine clinical practice of first-line…”
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Immune-related Adverse Events of Pembrolizumab in a Large Real-world Cohort of Patients With NSCLC With a PD-L1 Expression ≥ 50% and Their Relationship With Clinical Outcomes by Cortellini, Alessio, Friedlaender, Alex, Banna, Giuseppe L., Porzio, Giampiero, Bersanelli, Melissa, Cappuzzo, Federico, Aerts, Joachim G.J.V., Giusti, Raffaele, Bria, Emilio, Cortinovis, Diego, Grossi, Francesco, Migliorino, Maria R., Galetta, Domenico, Passiglia, Francesco, Berardi, Rossana, Mazzoni, Francesca, Di Noia, Vincenzo, Signorelli, Diego, Tuzi, Alessandro, Gelibter, Alain, Marchetti, Paolo, Macerelli, Marianna, Rastelli, Francesca, Chiari, Rita, Rocco, Danilo, Inno, Alessandro, Di Marino, Pietro, Mansueto, Giovanni, Zoratto, Federica, Santoni, Matteo, Tudini, Marianna, Ghidini, Michele, Filetti, Marco, Catino, Annamaria, Pizzutilo, Pamela, Sala, Luca, Occhipinti, Mario Alberto, Citarella, Fabrizio, Russano, Marco, Torniai, Mariangela, Cantini, Luca, Follador, Alessandro, Sforza, Vincenzo, Nigro, Olga, Ferrara, Miriam G., D’Argento, Ettore, Leonetti, Alessandro, Pettoruti, Linda, Antonuzzo, Lorenzo, Scodes, Simona, Landi, Lorenza, Guaitoli, Giorgia, Baldessari, Cinzia, Bertolini, Federica, Della Gravara, Luigi, Dal Bello, Maria Giovanna, Belderbos, Robert A., De Filippis, Marco, Cecchi, Cristina, Ricciardi, Serena, Donisi, Clelia, De Toma, Alessandro, Proto, Claudia, Addeo, Alfredo, Cantale, Ornella, Ricciuti, Biagio, Genova, Carlo, Morabito, Alessandro, Santini, Daniele, Ficorella, Corrado, Cannita, Katia

“…The role of immune-related adverse events (irAEs), as a surrogate predictor of the efficacy of checkpoint inhibitors, has not yet been described in the setting…”
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Post-progression outcomes of NSCLC patients with PD-L1 expression ≥ 50% receiving first-line single-agent pembrolizumab in a large multicentre real-world study by Cortellini, Alessio, Cannita, Katia, Tiseo, Marcello, Cortinovis, Diego L., Aerts, Joachim G.J.V., Baldessari, Cinzia, Giusti, Raffaele, Ferrara, Miriam G., D'Argento, Ettore, Grossi, Francesco, Guida, Annalisa, Berardi, Rossana, Morabito, Alessandro, Genova, Carlo, Antonuzzo, Lorenzo, Mazzoni, Francesca, De Toma, Alessandro, Signorelli, Diego, Gelibter, Alain, Targato, Giada, Rastelli, Francesca, Chiari, Rita, Rocco, Danilo, Gori, Stefania, De Tursi, Michele, Mansueto, Giovanni, Zoratto, Federica, Filetti, Marco, Bracarda, Sergio, Citarella, Fabrizio, Russano, Marco, Cantini, Luca, Nigro, Olga, Buti, Sebastiano, Minuti, Gabriele, Landi, Lorenza, Ricciardi, Serena, Migliorino, Maria R., Natalizio, Salvatore, Simona, Carnio, De Filippis, Marco, Metro, Giulio, Adamo, Vincenzo, Russo, Alessandro, Spinelli, Gian P., Di Maio, Massimo, Banna, Giuseppe L., Friedlaender, Alex, Addeo, Alfredo, Pinato, David J., Ficorella, Corrado, Porzio, Giampiero

“…Treatment sequencing with first-line immunotherapy, followed by second-line chemotherapy, is still a viable option for NSCLC patients with PD-L1 expression…”
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Impact of Signet-Ring Cell Histology in the Management of Patients with Non-Metastatic Gastric Cancer: Results from a Retrospective Multicenter Analysis Comparing FLOT Perioperative Chemotherapy vs. Surgery Followed by Adjuvant Chemotherapy by Giampieri, Riccardo, Baleani, Maria Giuditta, Bittoni, Alessandro, Rastelli, Francesca, Catalano, Vincenzo, Del Prete, Michela, Chiorrini, Silvia, Pinterpe, Giada, Graziano, Francesco, Giorgi, Francesca Chiara, Bisonni, Renato, Silva, Rosarita, Alessandroni, Paolo, Mencarini, Lara, Berardi, Rossana

“…FLOT perioperative chemotherapy represents the standard of care in non-metastatic gastric cancer patients. Signet-ring cell positivity is associated with a…”
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A novel, pathogenic dinucleotide deletion in the mitochondrial MT-TY gene causing myasthenia-like features by Lim, Albert Z., McMacken, Grace, Rastelli, Francesca, Oláhová, Monika, Baty, Karen, Hopton, Sila, Falkous, Gavin, Töpf, Ana, Lochmüller, Hanns, Marini-Bettolo, Chiara, McFarland, Robert, Taylor, Robert W.

“…•This novel m.5860delTA variant in the MT-TY gene that caused mitochondrial disorder can manifest clinical features suggestive of myasthenic syndromes.•This…”
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