Search Results - "Rassekh, S. Rod"

Evaluating the quantity, quality and size distribution of cell-free DNA by multiplex droplet digital PCR by Alcaide, Miguel, Cheung, Matthew, Hillman, Jack, Rassekh, S. Rod, Deyell, Rebecca J., Batist, Gerald, Karsan, Aly, Wyatt, Alexander W., Johnson, Nathalie, Scott, David W., Morin, Ryan D.

“…Cell-free DNA (cfDNA) has become a comprehensive biomarker in the fields of non-invasive cancer detection and monitoring, organ transplantation, prenatal…”
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Pharmacogenomic Prediction of Anthracycline-Induced Cardiotoxicity in Children by VISSCHER, Henk, ROSS, Colin J. D, DER PAL, Helena J. Van, BROWN, Andrew M. K, ROGERS, Paul C, PHILLIPS, Michael S, RIEDER, Michael J, CARLETON, Bruce C, HAYDEN, Michael R, ROD RASSEKH, S, BARHDADI, Amina, DUBE, Marie-Pierre, AL-SALOOS, Hesham, SANDOR, George S, CARON, Huib N, DALEN, Elvira C. Van, KREMER, Leontien C

“…Anthracycline-induced cardiotoxicity (ACT) is a serious adverse drug reaction limiting anthracycline use and causing substantial morbidity and mortality. Our…”
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Systematic Critical Review of Genetic Factors Associated with Cisplatin-induced Ototoxicity: Canadian Pharmacogenomics Network for Drug Safety 2022 Update by Scott, Erika N, Joseph, Akshaya A, Dhanda, Angie, Tanoshima, Reo, Brooks, Beth, Rassekh, S Rod, Ross, Colin J D, Carleton, Bruce C, Loucks, Catrina M

“…Cisplatin is commonly used to treat solid tumors; however, its use can be complicated by drug-induced hearing loss (ie, ototoxicity). The presence of certain…”
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Urgent need for "EBMM" in pediatric oncology: Evidence based medical marijuana by Rod Rassekh, S.

“…Marijuana has been used by many different civilizations for numerous different purposes, including its use for medical indications. Recently, there has been…”
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Waning Vaccine Immunity and Vaccination Responses in Children Treated for Acute Lymphoblastic Leukemia: A Canadian Immunization Research Network Study by Top, Karina A, Vaudry, Wendy, Morris, Shaun K, Pham-Huy, Anne, Pernica, Jeffrey M, Tapiéro, Bruce, Gantt, Soren, Price, Victoria E, Rassekh, S Rod, Sung, Lillian, McConnell, Athena, Rubin, Earl, Chawla, Rupesh, Halperin, Scott A

“…Abstract Background There is no uniform guideline for postchemotherapy vaccination of children with acute lymphoblastic leukemia (ALL). We evaluated waning…”
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Efficacy and safety of paediatric medicinal cannabis use: A scoping review by Pawliuk, Colleen, Chau, Briana, Rassekh, S Rod, McKellar, Terri, Siden, Harold (Hal)

“…Abstract Introduction The use of medicinal cannabis in the paediatric age group is increasing despite the lack of evidence for its efficacy or safety…”
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Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy by Carleton, Bruce C, Hayden, Michael R, Ross, Colin J D, Brooks, Beth, Phillips, Michael S, Rieder, Michael J, Rassekh, S Rod, Barhdadi, Amina, Visscher, Henk, Dubé, Marie-Pierre, Feroz-Zada, Yassamin, Brown, Andrew M K, Rogers, Paul C, Katzov-Eckert, Hagit

“…Cisplatin is a widely used and effective chemotherapeutic agent, although its use is restricted by the high incidence of irreversible ototoxicity associated…”
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Role of Cisplatin Dose Intensity and TPMT Variation in the Development of Hearing Loss in Children by Siemens, Angela, Brooks, Beth, Rassekh, S. Rod, Meijer, Annelot J.M., van den Heuvel-Eibrink, Mary M., Xu, Wei, Loucks, Catrina M., Ross, Colin J.D., Carleton, Bruce C.

“…Cisplatin, widely used in the treatment of solid tumors, causes permanent hearing loss in more than 60% of treated children. Previous studies have implicated…”
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A Systematic Review of Polygenic Models for Predicting Drug Outcomes by Siemens, Angela, Anderson, Spencer J., Rassekh, S. Rod, Ross, Colin J. D., Carleton, Bruce C.

“…Polygenic models have emerged as promising prediction tools for the prediction of complex traits. Currently, the majority of polygenic models are developed in…”
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VKORC1 and CYP2C9 genotypes are predictors of warfarin-related outcomes in children by Shaw, Kaitlyn, Amstutz, Ursula, Hildebrand, Claudette, Rassekh, S. Rod, Hosking, Martin, Neville, Kathleen, Leeder, J. Steven, Hayden, Michael R., Ross, Colin J., Carleton, Bruce C.

“…Background Despite substantial evidence supporting a pharmacogenetic approach to warfarin therapy in adults, evidence on the importance of genetics in warfarin…”
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Lessons learned from the application of whole-genome analysis to the treatment of patients with advanced cancers by Laskin, Janessa, Jones, Steven, Aparicio, Samuel, Chia, Stephen, Ch'ng, Carolyn, Deyell, Rebecca, Eirew, Peter, Fok, Alexandra, Gelmon, Karen, Ho, Cheryl, Huntsman, David, Jones, Martin, Kasaian, Katayoon, Karsan, Aly, Leelakumari, Sreeja, Li, Yvonne, Lim, Howard, Ma, Yussanne, Mar, Colin, Martin, Monty, Moore, Richard, Mungall, Andrew, Mungall, Karen, Pleasance, Erin, Rassekh, S Rod, Renouf, Daniel, Shen, Yaoqing, Schein, Jacqueline, Schrader, Kasmintan, Sun, Sophie, Tinker, Anna, Zhao, Eric, Yip, Stephen, Marra, Marco A

“…Given the success of targeted agents in specific populations it is expected that some degree of molecular biomarker testing will become standard of care for…”
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Targeted error-suppressed quantification of circulating tumor DNA using semi-degenerate barcoded adapters and biotinylated baits by Alcaide, Miguel, Yu, Stephen, Davidson, Jordan, Albuquerque, Marco, Bushell, Kevin, Fornika, Daniel, Arthur, Sarah, Grande, Bruno M., McNamara, Suzan, Tertre, Mathilde Couetoux du, Batist, Gerald, Huntsman, David G., Cavallone, Luca, Aguilar, Adriana, Basik, Mark, Johnson, Nathalie A., Deyell, Rebecca J., Rassekh, S. Rod, Morin, Ryan D.

“…Ultrasensitive methods for rare allele detection are critical to leverage the full potential offered by liquid biopsies. Here, we describe a novel molecular…”
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Comparative Tumor RNA Sequencing Analysis for Difficult-to-Treat Pediatric and Young Adult Patients With Cancer by Vaske, Olena M., Bjork, Isabel, Salama, Sofie R., Beale, Holly, Tayi Shah, Avanthi, Sanders, Lauren, Pfeil, Jacob, Lam, Du L., Learned, Katrina, Durbin, Ann, Kephart, Ellen T., Currie, Rob, Newton, Yulia, Swatloski, Teresa, McColl, Duncan, Vivian, John, Zhu, Jingchun, Lee, Alex G., Leung, Stanley G., Spillinger, Aviv, Liu, Heng-Yi, Liang, Winnie S., Byron, Sara A., Berens, Michael E., Resnick, Adam C., Lacayo, Norman, Spunt, Sheri L., Rangaswami, Arun, Huynh, Van, Torno, Lilibeth, Plant, Ashley, Kirov, Ivan, Zabokrtsky, Keri B., Rassekh, S. Rod, Deyell, Rebecca J., Laskin, Janessa, Marra, Marco A., Sender, Leonard S., Mueller, Sabine, Sweet-Cordero, E. Alejandro, Goldstein, Theodore C., Haussler, David

“…Importance Pediatric cancers are epigenetic diseases; therefore, considering tumor gene expression information is necessary for a complete understanding of the…”
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Abnormal liver transaminases and conjugated hyperbilirubinemia at presentation of acute lymphoblastic leukemia by Segal, Idit, Rassekh, S. Rod, Bond, Mason C., Senger, Christof, Schreiber, Richard A.

“…Background Acute lymphoblastic leukemia (ALL) is the most common malignancy in childhood. While hepatitis is a well‐known complication during the treatment…”
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Application of genomics to identify therapeutic targets in recurrent pediatric papillary thyroid carcinoma by Ronsley, Rebecca, Rassekh, S Rod, Shen, Yaoqing, Lee, Anna F, Jantzen, Colleen, Halparin, Jessica, Albert, Catherine, Hawkins, Douglas S, Amed, Shazhan, Rothstein, Ralph, Mungall, Andrew J, Dix, David, Blair, Geoffrey, Nadel, Helen, Jones, Steven J M, Laskin, Janessa, Marra, Marco A, J Deyell, Rebecca

“…Children with papillary thyroid carcinoma (PTC) may relapse despite response to radioactive iodine (RAI). Two children with multiply relapsed PTC underwent…”
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Tumor Variant Identification That Accounts for the Unique Molecular Landscape of Pediatric Malignancies by Lorentzian, Amanda, Biegel, Jaclyn A, Ostrow, D Gigi, Rolf, Nina, Liu, Chi-Chao, Rassekh, S Rod, Deyell, Rebecca J, Triche, Timothy, Schultz, Kirk R, Rozmus, Jacob, Reid, Gregor S D, Lim, C James, Lange, Philipp F, Maxwell, Christopher A

“…Precision oncology trials for pediatric cancers require rapid and accurate detection of genetic alterations. Tumor variant identification should interrogate…”
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Pharmacogenomics of serious adverse drug reactions in pediatric oncology by Ross, Colin J D, Visscher, Henk, Rassekh, S Rod, Castro-Pastrana, Lucila I, Shereck, Evan, Carleton, Bruce, Hayden, Michael R

“…Adverse drug reactions (ADRs) rank as one of the top ten leading causes of death and illness in the developed world. In cancer therapy, more patients are…”
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Gene-based drug therapy in children by Rassekh, S Rod, Rieder, Michael, ‘t Jong, Geert

“…Abstract The past two decades have seen enormous advancements in medical knowledge around the role of genetic factors of variability, both in human disease and…”
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Medicinal cannabis in children and adolescents with autism spectrum disorder: A scoping review by Fletcher, Sarah, Pawliuk, Colleen, Ip, Angie, Huh, Linda, Rassekh, S. Rod, Oberlander, Tim F., Siden, Harold

“…Background Autism spectrum disorder (ASD) is a neurodevelopmental condition estimated to affect 1 in 66 children in Canada and 1 in 270 individuals worldwide…”
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Cannabinoids for symptom management in children with cancer: A systematic review and meta-analysis by Chhabra, Manik, Ben-Eltriki, Mohamed, Paul, Arun, Lê, Mê-Linh, Herbert, Anthony, Oberoi, Sapna, Bradford, Natalie, Bowers, Alison, Rassekh, S Rod, Kelly, Lauren E

“…Despite the widespread use of medical cannabis, little is known regarding the safety, efficacy, and dosing of cannabis products in children with cancer. The…”
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