Search Results - "Raso, G. Mattace"
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Bisphenol A exacerbates anxiety-like behavior and neuroinflammation in prefrontal cortex of adult obese mice
Published in Life sciences (1973) (15-01-2023)“…Bisphenol A (BPA) is an endocrine-disrupting chemical inducing several damages such as neurotoxicity, immunotoxicity, and metabolic disorders. Obesity is the…”
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Targeting liver and adipose tissue in obese mice: Effects of a N-acylethanolamine mixture on insulin resistance and adipocyte reprogramming
Published in Biomedicine & pharmacotherapy (01-05-2024)“…N-acylethanolamines (NAEs) are endogenous lipid-signalling molecules involved in inflammation and energy metabolism. The potential pharmacological effect of…”
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Alkalihalobacillus clausii (formerly Bacillus clausii) spores lessen antibiotic-induced intestinal injury and reshape gut microbiota composition in mice
Published in Biomedicine & pharmacotherapy (01-07-2023)“…The antibiotic-induced intestinal injury (AIJ) is associated with diarrhoea and gastrointestinal discomfort. However, the pathological intestinal mechanisms…”
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Co-Micronized Palmitoylethanolamide and Rutin Associated With Hydroxytyrosol Recover Diabesity-Induced Hepatic Dysfunction in Mice: In Vitro Insights Into the Synergistic Effect
Published in Phytotherapy research (30-10-2024)“…Metabolic dysfunction-associated fatty liver disease (MAFLD) and diabesity (diabetes related to obesity) are interrelated since glucose and lipid alterations…”
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Palmitoylethanolamide Prevents Metabolic Alterations and Restores Leptin Sensitivity in Ovariectomized Rats
Published in Endocrinology (Philadelphia) (01-04-2014)“…It has been suggested a role of fatty acid ethanolamides in control of feeding behavior. Among these, palmitoylethanolamide (PEA) has not been directly…”
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Central administration of oxytocin reduces hyperalgesia in mice: Implication for cannabinoid and opioid systems
Published in Peptides (New York, N.Y. : 1980) (01-11-2012)“…► Icv oxytocin administration reduces carrageenan-induced hyperalgesia. ► CB1 receptor is involved in oxytocin-induced antihyperalgesic effect. ► μ- and…”
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Amyloid precursor protein, lipofuscin accumulation and expression of autophagy markers in aged bovine brain
Published in BMC veterinary research (13-04-2017)“…Autophagy is a highly regulated process involving the bulk degradation of cytoplasmic macromolecules and organelles in mammalian cells via the lysosomal…”
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Modulation of neuropathic and inflammatory pain by the endocannabinoid transport inhibitor AM404 [N-(4-hydroxyphenyl)-eicosa-5,8,11,14-tetraenamide]
Published in The Journal of pharmacology and experimental therapeutics (01-06-2006)“…The endocannabinoid system may serve important functions in the central and peripheral regulation of pain. In the present study, we investigated the effects of…”
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Palmitoylethanolamide Stimulation Induces Allopregnanolone Synthesis in C6 Cells and Primary Astrocytes: Involvement of Peroxisome-Proliferator Activated Receptor-α
Published in Journal of neuroendocrinology (01-07-2011)“…Palmitoylethanolamide (PEA) regulates many pathophysiological processes in the central nervous system, including pain perception, convulsions and…”
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Effects of non-dioxin-like polychlorinated biphenyl congeners (PCB 101, PCB 153 and PCB 180) alone or mixed on J774A.1 macrophage cell line: modification of apoptotic pathway
Published in Toxicology letters (10-04-2011)“…Non-dioxin-like polychlorinated biphenyls (PCBs) are stable and lipophilic chemicals that persist in the environment and tend to bioaccumulate in the food…”
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Cross‐talk between toll‐like receptor 4 (TLR4) and proteinase‐activated receptor 2 (PAR2) is involved in vascular function
Published in British journal of pharmacology (01-01-2013)“…Background and Purpose Proteinase‐activated receptors (PARs) and toll‐like receptors (TLRs) are involved in innate immune responses. The aim of this study was…”
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Evaluation of Placental Protein Modifications in Normotensive and Spontaneously Hypertensive Rats
Published in Placenta (Eastbourne) (01-05-2008)“…Abstract Hypertension in pregnancy is often associated to placental deficiency. Therefore several physiopathological modifications occur to sustain fetal…”
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AM404, an anandamide transport inhibitor, reduces plasma extravasation in a model of neuropathic pain in rat: Role for cannabinoid receptors
Published in Neuropharmacology (01-03-2008)“…Neuropathic pain consequent to peripheral nerve injury has been associated with local inflammation. Following noxious stimulation afferent fibres release…”
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Differential modification of inflammatory enzymes in J774A.1 macrophages by ochratoxin A alone or in combination with lipopolysaccharide
Published in Toxicology letters (10-09-2008)“…Ochratoxin A (OTA) is a fungal metabolite with controversial immunomodulatory effects. A prolonged in vivo exposure to the mycotoxin may result in impaired…”
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Synthesis and pharmacological evaluation of a set of N-[2-(alkylamino)ethyl]benzotriazol- X-yl isobutyramides acting as local anesthetics
Published in European journal of medicinal chemistry (1996)“…A set of N-[2-(alkylamino)ethyl]benzotriazol- X-yl isobutyramides have been synthesized and assayed in vivo for their local anesthetic activity and acute…”
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OS064. Contribute of the L-cysteine/ H2S pathway in placenta homeostasisin hypertensive disorders
Published in Pregnancy hypertension (01-07-2012)“…Hydrogen sulfide (H2S) is considered the third endogenous gas transmitter besides nitric oxide and carbon monoxide [1]. It is produced from L-cysteine or…”
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Partial deletion of the Akap1 gene promotes abnormalities in gut barrier function, gut microbiota composition and cardiac function during cardiovascular aging in mice
Published in European heart journal (28-10-2024)“…Abstract Background Cardiovascular aging is characterized by mitochondrial dysfunction, changes in intestinal permeability and microbiota composition…”
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