Search Results - "Rasmussen, I B"
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Effect of the IgM and IgA secretory tailpieces on polymerization and secretion of IgM and IgG
Published in The Journal of immunology (1950) (15-04-1996)“…Pentameric IgM and dimeric IgA both contain disulfide bonds between cysteines located in the secretory tailpieces of the heavy chains. To compare the…”
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2
Troybodies and pepbodies
Published in Biochemical Society transactions (01-08-2002)“…All antibodies (Abs) with effector function are produced in mammalian cells, whereas bacterial production is restricted to smaller targeting fragments (scFv…”
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3
First in-human study of 64Cu-DOTATATE positron emission tomography/computed tomography(PET/CT) in infective endocarditis: a prospective head-to-head comparison with 18-FDG PET/CT
Published in European heart journal (28-10-2024)“…Abstract Background Infective endocarditis (IE) is a severe and potentially fatal condition, which can be challenging to diagnose. Positron emission…”
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4
The Principle of Delivery of T Cell Epitopes to Antigen-Presenting Cells Applied to Peptides from Influenza Virus, Ovalbumin, and Hen Egg Lysozyme: Implications for Peptide Vaccination
Published in Proceedings of the National Academy of Sciences - PNAS (28-08-2001)“…Targeting of antigens to antigen-presenting cells (APCs) increases CD4+T cell activation, and this observation can be exploited in the development of new…”
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5
Structural requirements for incorporation of J chain into human IgM and IgA
Published in International immunology (01-01-2000)“…J chain is associated with pentameric IgM and dimeric IgA via disulfide bonds involving the penultimate cysteine residue in the secretory tailpiece of the μ or…”
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6
T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation
Published in The Journal of experimental medicine (04-06-2001)“…Type-B T cells raised against the immunodominant peptide in hen egg lysozyme (HEL(48-62)) do not respond to whole lysozyme, and this has been thought to…”
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Recombinant antibodies as carrier proteins for sub-unit vaccines: influence of mode of fusion on protein production and T-cell activation
Published in Journal of immunological methods (01-11-2000)“…A major objective in development of vaccines is the design of sub-unit vaccines with the ability to induce strong T-cell responses. For this purpose, T-cell…”
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"Troy-bodies": Recombinant Antibodies that Target T Cell Epitopes to Antigen Presenting Cells
Published in International reviews of immunology (2001)“…Targeting of antigens to antigen presenting cells (APC) results in enhanced antigen presentation and T cell activation. In this paper, we describe a novel…”
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Effectiveness of antibiotic prophylaxis in cholecystectomy: A prospective population-based study of 1171 cholecystectomies
Published in Scandinavian journal of gastroenterology (01-10-2012)“…Abstract Background. The aim of this study was to assess the benefit from antibiotic prophylaxis (AP) during cholecystectomy in a population-based cohort…”
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10
CD40/APC-specific antibodies with three T-cell epitopes loaded in the constant domains induce CD4+ T-cell responses
Published in Protein engineering, design and selection (01-03-2012)“…CD4+ T lymphocytes play a central role in the orchestration and maintenance of the adaptive immune response. Targeting of antigen to antigen presenting cells…”
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11
IgM secretory tailpiece drives multimerisation of bivalent scFv fragments in eukaryotic cells
Published in Immunotechnology (Amsterdam, Netherlands) (01-10-1998)“…The monoclonal antibody (mAb) TP-3 binds selectively to human and canine osteosarcoma (OS) cells and is therefore a potential candidate for use as a targeting…”
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12
Intestinal mucosal injury during porcine faecal peritonitis
Published in The European journal of surgery (01-10-1995)“…To assess the incidence of intestinal mucosal injury during faecal peritonitis in pigs, the relation of such lesions to haemodynamic variables, intramucosal pH…”
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13
Psychiatric caseness is a marker of major depressive episode in general practice
Published in Scandinavian journal of primary health care (01-12-2010)“…Abstract Objective. Screening for a major depressive episode (MDE) in high-risk groups of patients within the primary care setting has been suggested by…”
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14
Recombinant antibodies for delivery of antigen: a single loop between -strands in the constant region can accommodate long, complex and tandem T cell epitopes
Published in International immunology (01-03-2008)“…Recombinant antibodies are increasingly used for efficient delivery of T cell epitopes to antigen-presenting cells (APCs), both for vaccination purposes and…”
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15
Contextual problem solving
Published in Education (01-12-1990)“…An important challen'fQuacing us is how can we use computers creatively to teach aspects of problem solving? What is proposed in this paper is a stimulating…”
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Relationship between plasma volume reduction and plasma electrolyte changes after prolonged bicycle exercise, passive heating and diuretic dehydration
Published in Acta physiologica Polonica (01-09-1983)“…Plasma volume was decreased by prolonged bicycle exercise, by passive heating in warm water, by sauna dehydration, and by diuretically induced dehydration in…”
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17
‘Troy-bodies’: antibodies as vector proteins for T cell epitopes
Published in Biomolecular engineering (15-10-2001)“…A major objective in vaccine development is the design of reagents that give a strong, specific T cell response. Targeting of antigens to antigen presenting…”
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18
Efficient Delivery of T Cell Epitopes to APC by Use of MHC Class II-Specific Troybodies
Published in The Journal of immunology (1950) (01-03-2002)“…A major objective in vaccine development is the design of reagents that give strong, specific T cell responses. We have constructed a series of rAb with…”
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19
Changes in gut intramucosal pH and gut oxygen extraction ratio in a porcine model of peritonitis and hemorrhage
Published in Critical care medicine (01-11-1995)“…OBJECTIVE To establish the relationship between gut intramucosal pH and blood flow to the gut, gut oxygen delivery, and gut oxygen extraction ratio in a…”
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Effects of pneumoperitoneum on splanchnic hemodynamics: an experimental study in pigs
Published in The European journal of surgery (01-11-1995)“…To study the effects on splanchnic haemodynamics of pneumoperitoneum induced by carbon dioxide insufflation. Controlled experimental study. 11 Pigs weighing…”
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