Search Results - "Raskin, Grigory"
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Agreement between PDL1 immunohistochemistry assays and polymerase chain reaction in non-small cell lung cancer: CLOVER comparison study
Published in Scientific reports (03-03-2020)“…The goal of the CLOVER study was to perform a pairwise comparison of four tests based on the same patient population with non-small cell lung cancer (NSCLC):…”
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Novel ALK fusion partners in lung cancer
Published in Cancer letters (28-06-2015)“…Highlights • Combination of two distinct PCR assays is a highly reliable approach for detection of both known and new ALK translocations. • Two novel ALK…”
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Ethnicity-specific BRCA1, BRCA2, PALB2, and ATM pathogenic alleles in breast and ovarian cancer patients from the North Caucasus
Published in Breast cancer research and treatment (2024)“…Background Mountain areas of the North Caucasus host several large ethnic communities that have preserved their national identity over the centuries. Methods…”
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PCR-based analysis of PD-L1 RNA expression in lung cancer: comparison with commonly used immunohistochemical assays
Published in Annals of diagnostic pathology (01-08-2022)“…PD-L1 testing is currently performed by immunohistochemistry (IHC). We questioned whether the results of PCR-based measurement of PD-L1 RNA expression…”
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Rapid selection of BRCA1-proficient tumor cells during neoadjuvant therapy for ovarian cancer in BRCA1 mutation carriers
Published in Cancer letters (01-07-2017)“…Abstract Ovarian carcinomas (OC) often demonstrate rapid tumor shrinkage upon neoadjuvant chemotherapy (NACT). However, complete pathologic responses are very…”
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The Ring Study: an international comparison of PD-L1 diagnostic assays and their interpretation in non-small cell lung cancer, head and neck squamous cell cancer and urothelial cancer
Published in Pathology (01-02-2023)“…PD-L1 immunohistochemistry has been approved as a diagnostic assay for immunotherapy. However, an international comparison across multiple cancers is lacking…”
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Prognostic value of tumor growth kinetic parameters in prostate cancer patients
Published in Oncotarget (20-08-2019)“…The goal of this paper was to estimate the predictive value of kinetic parameters of tumor growth in 109 prostatic cancer (PCa) patients with the…”
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Primary cultures of human colon cancer as a model to study cancer stem cells
Published in Tumor biology (01-09-2016)“…The principal cause of death in cancer involves tumor progression and metastasis. Since only a small proportion of the primary tumor cells, cancer stem cells…”
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Complete Clinical Response of BRAF-Mutated Cholangiocarcinoma to Vemurafenib, Panitumumab, and Irinotecan
Published in Journal of gastrointestinal cancer (01-12-2016)Get full text
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Unusual Clinical Presentation of Gastrointestinal Clear Cell Sarcoma
Published in Gastrointestinal Tumors (29-05-2015)“…Background: Use of molecular assays is gradually becoming a mandatory part of the clinical management of soft tissue tumors, however the choice and the…”
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Challenges of FGFR2 Testing in Gastric Cancer
Published in Oncology reviews (14-12-2023)Get full text
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Agreement between FGFR2 immunohistochemistry assays and fluorescence in situ hybridization (FISH) in metastatic gastric cancer: A comparison study
Published in Journal of clinical oncology (01-02-2023)“…301 Background: FGFR2 status of a patient with metastatic gastric adenocarcinoma could be an important factor in determining optimal treatment strategy with…”
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Expression of Receptor Tyrosine Kinases on Peripheral Blood Mononuclear Cells and Tumor-Infiltrating Lymphocytes in Patients with Renal Cell Carcinoma and Healthy Donors
Published in Oncology (01-04-2020)“…Very little is known about receptor tyrosine kinase (RTK) expression on peripheral blood mononuclear cells (PBMC) in humans including renal cell carcinoma…”
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Alofanib in subsequent therapy for advanced gastric cancer: Final results from the phase Ib clinical trial
Published in Journal of clinical oncology (01-06-2022)“…e16077 Background: Alofanib (RPT835) is a first-in-class allosteric inhibitor that induces conformational changes in the extracellular domain of FGFR2. Here,…”
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Prognostic value of HER2, PD-L1 and RET mRNA expression in salivary gland tumor
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e18534 Background: The objective of our study was to evaluate the cytologically, morphologically and IGH detection of salivary gland (SGT),…”
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Detecting Microsatellite Instability in Endometrial, Colon, and Stomach Cancers Using Targeted NGS
Published in Cancers (01-10-2023)“…Purpose: To develop a method for testing the MSI based on targeted NGS. Methods: Based on the results of previous studies, 81 microsatellite loci with high…”
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RUSSCO-RSP comparative study of immunohistochemistry diagnostic assays for PD-L1 expression in urothelial bladder cancer
Published in Virchows Archiv : an international journal of pathology (01-12-2018)“…In this collaborative study by the Russian Society of Clinical Oncology and the Russian Society of Pathology, we assessed the concordance among three…”
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A first-in-human phase 1b study of a novel allosteric extracellular FGFR2 inhibitor alofanib in patients with refractory metastatic gastric cancer
Published in Journal of clinical oncology (01-02-2022)“…Abstract only 304 Background: FGFR2 promotes gastric cancer progression, suggesting that inhibition of FGFR2 may be an important therapeutic strategy. Alofanib…”
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A phase 1b study of the allosteric extracellular FGFR2 inhibitor alofanib in patients with pretreated advanced gastric cancer
Published in Investigational new drugs (01-04-2023)“…Summary Alofanib is a small-molecule allosteric extracellular FGFR2 inhibitor. We report safety and preliminary efficacy from the first-in-human phase 1b study…”
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RUSSCO-RSP study of immunohistochemistry (IHC) diagnostic assays for PD-L1 expression in urothelial cancer (UC)
Published in Journal of clinical oncology (20-02-2018)“…Abstract only 489 Background: This collaborative Russian Society of Clinical Oncology (RUSSCO) and Russian Society of Pathology (RSP) study assess the extent…”
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