Search Results - "Rashid, Mubasher"
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Combinatorial Cooperativity in miR200-Zeb Feedback Network can Control Epithelial–Mesenchymal Transition
Published in Bulletin of mathematical biology (01-05-2024)“…Carcinomas often utilize epithelial-mesenchymal transition (EMT) programs for cancer progression and metastasis. Numerous studies report SNAIL-induced…”
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Network topology metrics explaining enrichment of hybrid epithelial/mesenchymal phenotypes in metastasis
Published in PLoS computational biology (08-11-2022)“…Epithelial to Mesenchymal Transition (EMT) and its reverse—Mesenchymal to Epithelial Transition (MET) are hallmarks of metastasis. Cancer cells use this…”
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Feedforward Control of Plant Nitrate Transporter NRT1.1 Biphasic Adaptive Activity
Published in Biophysical journal (25-02-2020)“…Defective nitrate signaling in plants causes disorder in nitrogen metabolism, and it negatively affects nitrate transport systems, which toggle between high-…”
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Allosteric regulation of glutamate dehydrogenase deamination activity
Published in Scientific reports (05-10-2020)“…Glutamate dehydrogenase (GDH) is a key enzyme interlinking carbon and nitrogen metabolism. Recent discoveries of the GDH specific role in breast cancer,…”
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Adaptive Regulation of Nitrate Transceptor NRT1.1 in Fluctuating Soil Nitrate Conditions
Published in iScience (27-04-2018)“…Plant adaptation in variable soil nitrate concentrations involves sophisticated signaling and transport systems that modulate a variety of physiological and…”
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Organization of biogeochemical nitrogen pathways with switch-like adjustment in fluctuating soil redox conditions
Published in Royal Society open science (01-01-2017)“…Nitrogen is cycled throughout ecosystems by a suite of biogeochemical processes. The high complexity of the nitrogen cycle resides in an intricate interplay…”
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Logic-dependent emergence of multistability, hysteresis, and biphasic dynamics in a minimal positive feedback network with an autoloop
Published 08-04-2024“…Cellular decision-making (CDM) is a dynamic phenomenon often controlled by regulatory networks defining interactions between genes and transcription factor…”
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Robust regulation of hepatic pericentral amination by glutamate dehydrogenase kineticsElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ib00158k
Published 07-11-2016“…Impaired glutamate dehydrogenase (GDH) sensitivity to its inhibitors causes excessive insulin secretion by pancreatic beta-cells and defective ammonia…”
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Robust regulation of hepatic pericentral amination by glutamate dehydrogenase kinetics
Published in Integrative biology (Cambridge) (07-11-2016)“…Impaired glutamate dehydrogenase (GDH) sensitivity to its inhibitors causes excessive insulin secretion by pancreatic beta-cells and defective ammonia…”
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