Advances in laser-based diagnostic modalities for intraoperative tissue diagnosis in neurosurgery: current practices and future perspectives

Advances in laser-based diagnostic modalities for intraoperative tissue diagnosis in neurosurgery: current practices and future perspectives

This review assesses laser-based diagnostic modalities for intraoperative tissue diagnosis in neurosurgical oncology, emphasizing their utility in delineating tumor margins. Technologies such as optical coherence tomography, photoacoustic imaging, and confocal microscopy are scrutinized for their ca...

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Bibliographic Details
Published in:Egyptian journal of neurosurgery Vol. 39; no. 1; pp. 21 - 6
Main Authors: Pierre, Kevin, McCann, U. George, Razavi, Seyedeh Mehrsa Sadat, Patel, Anjali, Acevedo, Amanda, Cerillo, John, Raviprasad, Abheek, Zhou, Joseph, Rashdan, Dean, Lucke-Wold, Brandon
Format: Journal Article
Language:English
Published: Berlin/Heidelberg Springer Berlin Heidelberg 12-04-2024
Springer Nature B.V
SpringerOpen
Subjects:
Accuracy
Biopsy
Brain cancer
Brain research
Clinical outcomes
Infrared radiation
Lasers
Light
Magnetic resonance imaging
Medicine
Medicine & Public Health
Metabolism
Neurosurgery
Review
Spectrum analysis
Tomography
Tumors
Ultrasonic imaging
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Summary:This review assesses laser-based diagnostic modalities for intraoperative tissue diagnosis in neurosurgical oncology, emphasizing their utility in delineating tumor margins. Technologies such as optical coherence tomography, photoacoustic imaging, and confocal microscopy are scrutinized for their capability to enhance intraoperative discernment of neoplastic versus healthy tissue. We discuss the technical advancements, limitations related to depth penetration and resolution, and innovative approaches to mitigate these challenges. Economic and regulatory considerations pertinent to the clinical adoption of these technologies are also examined. The review highlights current clinical trials and research initiatives aiming to validate and standardize these applications. It concludes by highlighting the importance of ongoing research, cross-disciplinary cooperation, and professional training to integrate laser-based diagnostics into neurosurgical practice, with the ultimate goal of optimizing patient outcomes in brain tumor resection.
ISSN:2520-8225
2520-8225
DOI:10.1186/s41984-024-00292-7