Search Results - "Rashan, Luay"

Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo by Rashan, Luay J, Özenver, Nadire, Boulos, Joelle C, Dawood, Mona, Roos, Wynand P, Franke, Katrin, Papasotiriou, Ioannis, Wessjohann, Ludger A, Fiebig, Heinz-Herbert, Efferth, Thomas

“…Cancer drug resistance remains a major obstacle in clinical oncology. As most anticancer drugs are of natural origin, we investigated the anticancer potential…”
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Comparative Analysis of Pentacyclic Triterpenic Acid Compositions in Oleogum Resins of Different Boswellia Species and Their In Vitro Cytotoxicity against Treatment-Resistant Human Breast Cancer Cells by Schmiech, Michael, Lang, Sophia J, Werner, Katharina, Rashan, Luay J, Syrovets, Tatiana, Simmet, Thomas

“…Pentacyclic triterpenic acids from oleogum resins of species are of considerable therapeutic interest. Yet, their pharmaceutical development is hampered by…”
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Comparative Investigation of Frankincense Nutraceuticals: Correlation of Boswellic and Lupeolic Acid Contents with Cytokine Release Inhibition and Toxicity against Triple-Negative Breast Cancer Cells by Schmiech, Michael, Lang, Sophia J, Ulrich, Judith, Werner, Katharina, Rashan, Luay J, Syrovets, Tatiana, Simmet, Thomas

“…For centuries, frankincense extracts have been commonly used in traditional medicine, and more recently, in complementary medicine. Therefore, frankincense…”
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Trimethylamine-N-oxide and cerebral stroke risk: A review by Dolkar, Phurbu, Deyang, Tenzin, Anand, Nikhilesh, Rathipriya, Annan Gopinath, Hediyal, Tousif Ahmed, Chandrasekaran, Vichitra, Krishnamoorthy, Naveen Kumar, Gorantla, Vasavi Rakesh, Bishir, Muhammed, Rashan, Luay, Chang, Sulie L., Sakharkar, Meena Kishore, Yang, Jian, Chidambaram, Saravana Babu

“…Trimethylamine-N-oxide (TMAO) is a gut microbiota-derived metabolite produced by the action of gut microbiota and the hepatic enzyme Flavin Mono‑oxygenase 3…”
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In Vitro Antimicrobial Activity of Frankincense Oils from Boswellia sacra Grown in Different Locations of the Dhofar Region (Oman) by Di Stefano, Vita, Schillaci, Domenico, Cusimano, Maria Grazia, Rishan, Mohammed, Rashan, Luay

“…Frankincense essential oils from have been commonly used to treat microbial infections from as early as the 11th century. The main feature of the plant is its…”
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Antidiabetic and antioxidant properties of Boswellia sacra oleo-gum in streptozotocin-induced diabetic rats by Al-Matubsi, Hisham, Rashan, Luay, Aburayyan, Walid, Al Hanbali, Othman, Abuarqoub, Duaa, Efferth, Thomas

“…Diabetes is a metabolic disorder requiring the administration of insulin or other oral hypoglycemic medicines. Although metformin is a popular prescription for…”
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Potential Antimicrobial Activity of Galloyl-Flavonoid Glycosides From Woodfordia uniflora Against Methicillin-Resistant Staphylococcus aureus by Yu, Jae Sik, Kim, Ji-Hoon, Rashan, Luay, Kim, Inseo, Lee, Wonsik, Kim, Ki Hyun

“…Antibiotic-resistant infections are a growing problem; to combat multi-drug resistant bacterial infections, antibiotics with novel mechanisms of action are…”
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Autophagy machinery plays an essential role in traumatic brain injury-induced apoptosis and its related behavioral abnormalities in mice: focus on Boswellia Sacra gum resin by Interdonato, Livia, Marino, Ylenia, Impellizzeri, Daniela, D'Amico, Ramona, Siracusa, Rosalba, Fusco, Roberta, Cammilleri, Gaetano, Pantano, Licia, Modafferi, Sergio, Abdelhameed, Ali S, Fritsch, Tilman, Rashan, Luay J, Cuzzocrea, Salvatore, Calabrese, Vittorio, Cordaro, Marika, Di Paola, Rosanna

“…Traumatic brain injury (TBI) is described as a structural damage or physiological disturbance of brain function that occurs after trauma and causes disability…”
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Acetylsalicylic acid improves cognitive performance in sleep deprived adult Zebrafish ( Danio rerio ) model by Bishir, Muhammed, Aslam, Muhammed, Bhat, Abid, Ray, Bipul, Elumalai, Preetham, R, Jyothi Priya, Rashan, Luay, Yang, Jian, Chang, Sulie L, Essa, Musthafa Mohamed, Sakharkar, Meena Kishore, Chidambaram, Saravana Babu

“…Sleep deprivation (SD) is commonly associated with decreased attention, reduced responsiveness to external stimuli, and impaired locomotor and cognitive…”
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Mitochondria-Endoplasmic Reticulum Crosstalk in Parkinson's Disease: The Role of Brain Renin Angiotensin System Components by Sunanda, Tuladhar, Ray, Bipul, Mahalakshmi, Arehally M, Bhat, Abid, Rashan, Luay, Rungratanawanich, Wiramon, Song, Byoung-Joon, Essa, Musthafa Mohamed, Sakharkar, Meena Kishore, Chidambaram, Saravana Babu

“…The past few decades have seen an increased emphasis on the involvement of the mitochondrial-associated membrane (MAM) in various neurodegenerative diseases,…”
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Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes by Hakkim, Faruck L, Bakshi, Hamid A, Khan, Shabia, Nasef, Mohamad, Farzand, Rabia, Sam, Smitha, Rashan, Luay, Al-Baloshi, Mohammed S, Abdo Hasson, Sidgi Syed Anwar, Jabri, Ali Al, McCarron, Paul A, Tambuwala, Murtaza M

“…Melanoma is a deadly form of malignancy and according to the World Health Organization 132,000 new cases of melanoma are diagnosed worldwide each year…”
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Dietary Crocin Reverses Melanoma Metastasis by Bakshi, Hamid A, Hakkim, Faruck Lukmanul, Sam, Smitha, Javid, Farideh, Rashan, Luay

“…Crocus sativus and its bioactive constituent crocin are well known for anti-tumor potential in different models. However, the efficacy of crocin on in-vivo…”
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Frankincense: A neuronutrient to approach Parkinson’s disease treatment by Calabrese, Vittorio, Osakabe, Naomi, Khan, Foziya, Wenzel, Uwe, Modafferi, Sergio, Nicolosi, Lidia, Fritsch, Tilman, Jacob, Ursula M., Abdelhameed, Ali S., Rashan, Luay

“…Parkinson’s disease (PD), characterized by tremor, slowness of movement, stiffness, and poor balance, is due to a significant loss of dopaminergic neurons in…”
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Characterization of the anticancer properties of monoglycosidic cardenolides isolated from Nerium oleander and Streptocaulon tomentosum by Rashan, Luay J., Franke, Katrin, Khine, Myint Myint, Kelter, Gerhard, Fiebig, Heinz H., Neumann, Joachim, Wessjohann, Ludger A.

“…Monoglycosidic cardenolides possessing the 3β,14β-dihydroxy-5β-card-20(22)-enolide structure with or without an acetoxy group at C-16 are the most active…”
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Anti-Inflammatory Effects of a Polyphenol, Catechin-7,4'- O -Digallate, from Woodfordia uniflora by Regulating NF-κB Signaling Pathway in Mouse Macrophages by Kim, Eui Jin, Seo, Ji Bin, Yu, Jae Sik, Lee, Seoyoung, Lim, Jae Sung, Choi, Jeong Uk, Lee, Chang-Min, Rashan, Luay, Kim, Ki Hyun, Cho, Young-Chang

“…Inflammation is a defense mechanism that protects the body from infections. However, chronic inflammation causes damage to body tissues. Thus, controlling…”
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Larvicidal effect of zirconium oxide nanoparticles in protoscoleces of hydatid cysts in the laboratory and mice by Mahmoud, Zina A., Ali, Asmaa A., Rashan, Luay J.

“…The research focuses on the effect of zirconium oxide nanoparticles in the activity of protoscoleces of Echinococcus granulosus in the lab., seven strengths of…”
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Synthesis, crystal structure and initial biological evaluation of the new enantiomerically pure chiral palladium(II) complex trans-bis{endo-(1 R)-1,7,7-trimethylbicyclo[2.2.1]-heptan-2-amino}palladium(II)dichloride by Abu-Surrah, Adnan S, Al-Allaf, Talal A.K, Rashan, Luay J, Klinga, Martti, Leskelä, Markku

“…The palladium(II) complex trans-bis{( R)-(+)-bornylamino}palladium(II) dichloride was synthesised and characterised. The solid state structure of the complex…”
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Palladium(II) and platinum(II) complexes of (1R,2R)-(−)-1,2-diaminocyclohexane (DACH) with various carboxylato ligands and their cytotoxicity evaluation by Al-Allaf, Talal A.K., Rashan, Luay J., Ketler, Gerhard, Fiebig, Heinz-Herbert, Al-Dujaili, Amar H.

“…Several palladium(II) and platinum(II) complexes analogous to oxaliplatin, bearing the enantiomerically pure (1R,2R)‐(−)‐1,2‐diaminocyclohexane (DACH) ligand,…”
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Antifungal Phenols from Woodfordia uniflora Collected in Oman by Yu, Jae Sik, Park, Minji, Pang, Changhyun, Rashan, Luay, Jung, Won Hee, Kim, Ki Hyun

“…Woodfordia uniflora is a flowering shrub unique to the Dhofar region of Oman and is used locally as a sedative and remedy for skin infection. However, no study…”
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Organotin(IV) complexes with various donor ligands and their cytotoxicity against tumour cell lines. Part(I): R2SnCl2 with Schiff bases; unusual CN bond cleavage of the bases and X-ray structures of the ionic products formed by Al-Allaf, Talal A. K., Rashan, Luay J., Stelzner, Axel, Powell, Douglas R.

“…Several Schiff bases derived from salicylaldehyde and aminopyridines were found to coordinate with Me2SnCl2 in 1:1 or 1:2 (tin:base) molar ratio in…”
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