Search Results - "Ras̆lová, K."
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The molecular genetic background of familial hypercholesterolemia: data from the Slovak nation-wide survey
Published in Physiological research (01-01-2017)“…Familial hypercholesterolemia (FH) is most frequently caused by LDLR or APOB mutations. Therefore, the aim of our study was to examine the genetic background…”
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Insulin detemir and insulin aspart: a promising basal-bolus regimen for type 2 diabetes
Published in Diabetes research and clinical practice (01-11-2004)“…This trial compared the efficacy and safety of basal-bolus therapy using either the soluble basal insulin analogue insulin detemir (IDet) in combination with…”
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Efficacy and safety of insulin detemir once daily in combination with sitagliptin and metformin: the TRANSITION randomized controlled trial
Published in Diabetes, obesity & metabolism (01-03-2011)“…Aim: The aim of this trial was to evaluate the efficacy and safety of the combination of once-daily insulin detemir (IDet) and sitagliptin (SITA) versus SITA ±…”
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Molecular analysis of genes involved in lipoprotein lipase deficiency in Slovak patients with familial chylomicronemia
Published in Atherosclerosis (01-09-2016)Get full text
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Association of metabolic and genetic factors with cholesterol esterification rate in HDL plasma and atherogenic index of plasma in a 40 years old Slovak population
Published in Physiological research (01-01-2011)“…We assessed association between novel biomarkers of cardiovascular disease and conventional factors in 40 years old subjects (208 men and 266 women) from the…”
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DNA diagnostics of familial hypercholesterolemia: Slovak experience
Published in Atherosclerosis (01-07-2015)Get full text
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DNA damage and antioxidants; fluctuations through the year in a central European population group
Published in Food and chemical toxicology (01-08-2002)“…Dietary antioxidant levels in the blood depend on intake of fruits and vegetables and therefore might be expected to show seasonal variation. A group of…”
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Molecular-genetic aspects of familial hypercholesterolemia
Published in Endocrine regulations (Bratislava) (01-07-2015)“…Familial hypercholesterolemia (FH) is the world's most abundant and the most common heritable disorder of lipid metabolism. The prevalence of the disease in…”
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Nutritional supplementation with antioxidants decreases chromosomal damage in humans
Published in Mutagenesis (01-07-2003)“…In order to investigate the effects of antioxidant supplementation on chromosome damage, a 3 month antioxidant supplementation trial was conducted on groups of…”
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Comet assay in human biomonitoring studies: Reliability, validation, and applications
Published in Environmental and molecular mutagenesis (1997)“…The comet assay (single‐cell gel electrophoresis), which measures DNA strand breaks at the level of single cells, is very easily applied to human lymphocytes,…”
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DNA Damage in Diabetes: Correlation with a Clinical Marker
Published in Free radical biology & medicine (01-08-1998)“…Levels of DNA damage in groups of 10 patients with insulin-dependent diabetes mellitus and 10 matched controls were compared using the comet assay; DNA strand…”
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Folate levels determine effect of antioxidant supplementation on micronuclei in subjects with cardiovascular risk
Published in Mutagenesis (01-11-2004)“…We have investigated the effect of modest supplementation with α-tocopherol (100 mg/day), β-carotene (6 mg/day), vitamin C (100 mg/day) and selenium (50…”
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Antioxidant supplementation reduces inter-individual variation in markers of oxidative damage
Published in Free radical research (01-06-2005)“…The aim of this study was to examine the effect of antioxidant supplementation on oxidative damage and chromosome stability in middle-aged men, smokers and…”
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Effect of C677T methylenetetrahydrofolate reductase gene polymorphism on plasma homocysteine levels in ethnic groups
Published in Physiological research (2004)“…The objective of this study was to examine plasma homocysteine levels and C677T methylenetetrahydrofolate reductase (MTHFR) gene polymorphism in two ethnic…”
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EU-Wide Cross-Sectional Observational Study of Lipid-Modifying Therapy Use in Secondary and Primary Care: the DA VINCI study
Published in European journal of preventive cardiology (20-09-2021)“…To provide contemporary data on the implementation of European guideline recommendations for lipid-lowering therapies (LLTs) across different settings and…”
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Serum lipid resistance to oxidation and uric acid levels in subjects with Down's syndrome
Published in Physiological research (2000)“…In subjects with Down's syndrome (DS) increased oxidative stress and consequent oxidative cell damage have been reported. The aim of this study was to assess…”
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Atherogenic lipoprotein profile in families with and without history of early myocardial infarction
Published in Physiological research (2001)“…In this study we compared several parameters characterizing differences in the lipoprotein profile between members of families with a positive or negative…”
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Risk factors for atherosclerosis in survivors of myocardial infarction and their spouses: Comparison to controls without personal and family history of atherosclerosis
Published in Metabolism, clinical and experimental (01-01-2001)“…To explore the hypothesis that an interplay between genetic and environmental factors contributes to the development of coronary atherosclerosis, we compared…”
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