Search Results - "Rare cancers and therapy"

Evolving Paradigms in the Management of Multiple Myeloma: Novel Agents and Targeted Therapies by Larsen, Jeremy T., Kumar, Shaji

“…Multiple myeloma (MM) is a clonal plasma cell disorder defined by bone marrow infiltration and osteolytic bone lesions and is the second most common…”
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Reviewing Challenges in the Diagnosis and Treatment of Lentigo Maligna and Lentigo-Maligna Melanoma by Juhász, Margit L. W., Marmur, Ellen S.

“…Lentigo maligna (LM) and lentigo-maligna melanoma (LMM) are pigmented skin lesions that may exist on a continuous clinical and pathological spectrum of…”
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Targeted Therapy in Oropharyngeal Squamous Cell Carcinoma: The Implications of HPV for Therapy by Hay, Ashley, Ganly, Ian

“…Oropharyngeal cancers caused by human papillomaviruses (HPV) have a different epidemiology, prognosis, genetic mutational landscape, response to treatment, and…”
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Acute Myeloid Leukemia in the Elderly Patient: New Strategies by Thomas, Xavier

“…Although selected older adults with acute myeloid leukemia can benefit from intensive therapies, recent evidences support the use of lower-intensity therapies…”
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Molecular Monitoring as a Path to Cure Acute Promyelocytic Leukemia by De Angelis, Federico, Breccia, Massimo

“…Acute promyelocytic leukemia (APL) is a molecularly well-defined disease, characterized by a specific chromosomal translocation; the improvement in biologic…”
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Treatment of Adult Soft Tissue Sarcomas: An Overview by Arifi, Samia, Belbaraka, Rhizlan, Rahhali, Rabie, Ismaili, Nabil

“…Sarcomas are uncommon malignancies accounting for about 1% of all adult malignancies. Sarcomas are a heterogeneous group of tumors which includes more than 100…”
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Bosutinib for Chronic Myeloid Leukemia by Breccia, Massimo, Binotto, Gianni

“…In recent years the availability of several tyrosine kinase inhibitors (TKI) in the therapeutic armamentarium for chronic myeloid leukemia has dramatically…”
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An Overview on the Sequential Treatment of Pancreatic Neuroendocrine Tumors (pNETs) by Alonso-Gordoa, Teresa, Díez, Juan José, Molina, Javier, Reguera, Pablo, Martínez-Sáez, Olga, Grande, Enrique

“…Patients suffering from pancreatic neuroendocrine tumors (pNETs) are now candidates to receive novel approved drugs that have demonstrated benefit in disease…”
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Efficacy and Safety of Aflibercept and Its Role in the Treatment of Metastatic Colorectal Cancer by Salem, Mohamed E., El-Refai, Sherif M.

“…Background Vascular endothelial growth factor (VEGF) and related pathway elements are critically important in the pathogenesis, growth, and development of…”
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Expression Patterns of Snail1, E-Cadherin and N-Cadherin Proteins in the Developing Kidney and in Wilms’ Tumor (Nephroblastoma) by Schmid, Sebastian Christoph, Blechschmidt, Kareen, Schulz, Stefan, Becker, Karl Friedrich, Weirich, Gregor

“…Introduction Snail1 is a transcription factor that suppresses E-cadherin. The roles of Snail1 and E-cadherin in mesenchyme–epithelial transition (MET) are not…”
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Rectal Melanoma with Multiple Metastases: A Rare and Aggressive Tumor by Ibnian, Ali M., Nagaraja, Vinayak, Eslick, Guy D., Kalantar, Jamshid S.

“…Introduction Rectal melanoma is one type of mucosal melanoma and accounts for fewer than 2% of all mucosal melanomas; it is a rare, aggressive disease with…”
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Letter from the Editor by Capdevila, Jaume

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