Search Results - "Rapsomaniki, Maria"

EasyFRAP-web: a web-based tool for the analysis of fluorescence recovery after photobleaching data by Koulouras, Grigorios, Panagopoulos, Andreas, Rapsomaniki, Maria A, Giakoumakis, Nickolaos N, Taraviras, Stavros, Lygerou, Zoi

“…Abstract Understanding protein dynamics is crucial in order to elucidate protein function and interactions. Advances in modern microscopy facilitate the…”
Get full text

Spatial protein heterogeneity analysis in frozen tissues to evaluate tumor heterogeneity by Fomitcheva-Khartchenko, Anna, Rapsomaniki, Maria Anna, Sobottka, Bettina, Schraml, Peter, Kaigala, Govind V

“…A new workflow for protein-based tumor heterogeneity probing in tissues is here presented. Tumor heterogeneity is believed to be key for therapy failure and…”
Get full text

A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer by Wagner, Johanna, Rapsomaniki, Maria Anna, Chevrier, Stéphane, Anzeneder, Tobias, Langwieder, Claus, Dykgers, August, Rees, Martin, Ramaswamy, Annette, Muenst, Simone, Soysal, Savas Deniz, Jacobs, Andrea, Windhager, Jonas, Silina, Karina, van den Broek, Maries, Dedes, Konstantin Johannes, Rodríguez Martínez, Maria, Weber, Walter Paul, Bodenmiller, Bernd

“…Breast cancer is a heterogeneous disease. Tumor cells and associated healthy cells form ecosystems that determine disease progression and response to therapy…”
Get full text

Multi-step Loading of Human Minichromosome Maintenance Proteins in Live Human Cells by Symeonidou, Ioanna-Eleni, Kotsantis, Panagiotis, Roukos, Vassilis, Rapsomaniki, Maria-Anna, Grecco, Hernán E., Bastiaens, Philippe, Taraviras, Stavros, Lygerou, Zoi

“…Once-per-cell cycle replication is regulated through the assembly onto chromatin of multisubunit protein complexes that license DNA for a further round of…”
Get full text

Quantification of tumor heterogeneity: from data acquisition to metric generation by Kashyap, Aditya, Rapsomaniki, Maria Anna, Barros, Vesna, Fomitcheva-Khartchenko, Anna, Martinelli, Adriano Luca, Rodriguez, Antonio Foncubierta, Gabrani, Maria, Rosen-Zvi, Michal, Kaigala, Govind

“…Tumors are unique and complex ecosystems, in which heterogeneous cell subpopulations with variable molecular profiles, aggressiveness, and proliferation…”
Get full text

easyFRAP: an interactive, easy-to-use tool for qualitative and quantitative analysis of FRAP data by RAPSOMANIKI, Maria Anna, KOTSANTIS, Panagiotis, SYMEONIDOU, Loanna-Eleni, GIAKOUMAKIS, Nickolaos-Nikiforos, TARAVIRAS, Stavros, LYGEROU, Zoi

“…We present easyFRAP, a versatile tool that assists quantitative and qualitative analysis of fluorescence recovery after photobleaching (FRAP) data. The user…”
Get full text

CellCycleTRACER accounts for cell cycle and volume in mass cytometry data by Rapsomaniki, Maria Anna, Lun, Xiao-Kang, Woerner, Stefan, Laumanns, Marco, Bodenmiller, Bernd, Martínez, María Rodríguez

“…Recent studies have shown that cell cycle and cell volume are confounding factors when studying biological phenomena in single cells. Here we present a…”
Get full text

Analysis of Protein Kinetics Using Fluorescence Recovery After Photobleaching (FRAP) by Giakoumakis, Nickolaos Nikiforos, Rapsomaniki, Maria Anna, Lygerou, Zoi

“…Fluorescence recovery after photobleaching (FRAP) is a cutting-edge live-cell functional imaging technique that enables the exploration of protein dynamics in…”
Get more information

ScLinear predicts protein abundance at single-cell resolution by Hanhart, Daniel, Gossi, Federico, Rapsomaniki, Maria Anna, Kruithof-de Julio, Marianna, Chouvardas, Panagiotis

“…Single-cell multi-omics have transformed biomedical research and present exciting machine learning opportunities. We present scLinear, a linear…”
Get full text

scQUEST: Quantifying tumor ecosystem heterogeneity from mass or flow cytometry data by Martinelli, Adriano Luca, Wagner, Johanna, Bodenmiller, Bernd, Rapsomaniki, Maria Anna

“…With mass and flow cytometry, millions of single-cell profiles with dozens of parameters can be measured to comprehensively characterize complex tumor…”
Get full text

Inference of protein kinetics by stochastic modeling and simulation of fluorescence recovery after photobleaching experiments by Rapsomaniki, Maria Anna, Cinquemani, Eugenio, Giakoumakis, Nickolaos Nikiforos, Kotsantis, Panagiotis, Lygeros, John, Lygerou, Zoi

“…Fluorescence recovery after photobleaching (FRAP) is a functional live cell imaging technique that permits the exploration of protein dynamics in living cells…”
Get full text

IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover by Vakaloglou, Katerina M., Chrysanthis, Georgios, Rapsomaniki, Maria Anna, Lygerou, Zoi, Zervas, Christos G.

Get full text

ATHENA: analysis of tumor heterogeneity from spatial omics measurements by Martinelli, Adriano Luca, Rapsomaniki, Maria Anna

“…Abstract Summary Tumor heterogeneity has emerged as a fundamental property of most human cancers, with broad implications for diagnosis and treatment…”
Get full text

Co-existence of phenylketonuria and Fabry disease on a 3 year-old boy: case report by Concolino, Daniela, Rapsomaniki, Maria, Disabella, Eliana, Sestito, Simona, Pascale, Maria G, Moricca, Maria T, Bonapace, Giuseppe, Arbustini, Elisea, Strisciuglio, Pietro

“…The co-existence of two genetically distinct metabolic disorders in the same patient has rarely been reported. Phenylketonuria (PKU) is an inborn error of the…”
Get full text

A novel pipeline method for the preprocessing of Mass spectrometry proteomics data by Rapsomaniki, Maria Anna V, Zerefos, Panagiotis G, Theofilatos, Konstantinos A, Likothanassis, Spiridon D, Tsakalidis, Athanasios K, Mavroudi, Seferina P

“…Mass spectrometry based methodologies allow us to analyze complex mixtures of proteins from biological samples in order to identify important proteomic…”
Get full text

Matching single cells across modalities with contrastive learning and optimal transport by Gossi, Federico, Pati, Pushpak, Chouvardas, Panagiotis, Martinelli, Adriano Luca, Kruithof-de Julio, Marianna, Rapsomaniki, Maria Anna

“…Abstract Understanding the interactions between the biomolecules that govern cellular behaviors remains an emergent question in biology. Recent advances in…”
Get full text

CK1δ restrains lipin-1 induction, lipid droplet formation and cell proliferation under hypoxia by reducing HIF-1α/ARNT complex formation by Kourti, Maria, Ikonomou, Georgia, Giakoumakis, Nikolaos-Nikiforos, Rapsomaniki, Maria Anna, Landegren, Ulf, Siniossoglou, Symeon, Lygerou, Zoi, Simos, George, Mylonis, Ilias

“…Proliferation of cells under hypoxia is facilitated by metabolic adaptation, mediated by the transcriptional activator Hypoxia Inducible Factor-1 (HIF-1)…”
Get full text

IPP Complex Reinforces Adhesion by Relaying Tension-Dependent Signals to Inhibit Integrin Turnover by Vakaloglou, Katerina M., Chrysanthis, Georgios, Rapsomaniki, Maria Anna, Lygerou, Zoi, Zervas, Christos G.

“…Cytoskeleton-mediated forces regulate the assembly and function of integrin adhesions; however, the underlying mechanisms remain unclear. The tripartite IPP…”
Get full text

In silico analysis of DNA re-replication across a complete genome reveals cell-to-cell heterogeneity and genome plasticity by Rapsomaniki, Maria Anna, Maxouri, Stella, Nathanailidou, Patroula, Garrastacho, Manuel Ramirez, Giakoumakis, Nickolaos Nikiforos, Taraviras, Stavros, Lygeros, John, Lygerou, Zoi

“…Abstract DNA replication is a complex and remarkably robust process: despite its inherent uncertainty, manifested through stochastic replication timing at a…”
Get full text

Hybrid quantum-classical graph neural networks for tumor classification in digital pathology by Ray, Anupama, Madan, Dhiraj, Patil, Srushti, Rapsomaniki, Maria Anna, Pati, Pushpak

“…Advances in classical machine learning and single-cell technologies have paved the way to understand interactions between disease cells and tumor…”
Get full text