Search Results - "Rappocciolo, Giovanna"

Cholesterol Metabolism in Antigen-Presenting Cells and HIV-1 Trans-Infection of CD4 + T Cells by Okpaise, Daniel, Sluis-Cremer, Nicolas, Rappocciolo, Giovanna, Rinaldo, Charles R

“…Antiretroviral therapy (ART) provides an effective method for managing HIV-1 infection and preventing the onset of AIDS; however, it is ineffective against the…”
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B Lymphocytes, but Not Dendritic Cells, Efficiently HIV-1 Trans Infect Naive CD4 + T Cells: Implications for the Viral Reservoir by Gerberick, Abigail, DeLucia, Diana C, Piazza, Paolo, Alaoui-El-Azher, Mounia, Rinaldo, Charles R, Sluis-Cremer, Nicolas, Rappocciolo, Giovanna

“…Insight into the establishment and maintenance of HIV-1 infection in resting CD4 T cell subsets is critical for the development of therapeutics targeting the…”
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Human Herpesvirus 8 Infects and Replicates in Primary Cultures of Activated B Lymphocytes through DC-SIGN by RAPPOCCIOLO, Giovanna, HENSLER, Heather R, JAIS, Mariel, REINHART, Todd A, PEGU, Amarendra, JENKINS, Frank J, RINALDO, Charles R

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DC-SIGN Is a Receptor for Human Herpesvirus 8 on Dendritic Cells and Macrophages by Rappocciolo, Giovanna, Jenkins, Frank J, Hensler, Heather R, Piazza, Paolo, Jais, Mariel, Borowski, Luann, Watkins, Simon C, Rinaldo, Charles R., Jr

“…Human herpesvirus 8 (HHV-8) causes Kaposi's sarcoma and pleural effusion lymphoma. In this study, we show that dendritic cell-specific ICAM-3 grabbing…”
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Selective induction of CTL helper rather than killer activity by natural epitope variants promotes dendritic cell-mediated HIV-1 dissemination by Mailliard, Robbie B, Smith, Kellie N, Fecek, Ronald J, Rappocciolo, Giovanna, Nascimento, Eduardo J M, Marques, Ernesto T, Watkins, Simon C, Mullins, James I, Rinaldo, Charles R

“…The ability of HIV-1 to rapidly accumulate mutations provides the virus with an effective means of escaping CD8(+) CTL responses. In this study, we describe…”
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Fifty Percent Tissue Culture Infective Dose Assay for Determining the Titer of Infectious Human Herpesvirus 8 by Nadgir, Sagar V, Hensler, Heather R, Knowlton, Emilee R, Rinaldo, Charles R, Rappocciolo, Giovanna, Jenkins, Frank J

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Monofunctional and Polyfunctional CD8+ T Cell Responses to Human Herpesvirus 8 Lytic and Latency Proteins by Lepone, Lauren, Rappocciolo, Giovanna, Knowlton, Emilee, Jais, Mariel, Piazza, Paolo, Jenkins, Frank J, Rinaldo, Charles R

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DC-SIGN on B lymphocytes is required for transmission of HIV-1 to T lymphocytes by Rappocciolo, Giovanna, Piazza, Paolo, Fuller, Craig L, Reinhart, Todd A, Watkins, Simon C, Rowe, David T, Jais, Mariel, Gupta, Phalguni, Rinaldo, Charles R

“…Infection of T cells by HIV-1 can occur through binding of virus to dendritic cell (DC)-specific ICAM-3 grabbing nonintegrin (DC-SIGN) on dendritic cells and…”
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Human herpesvirus 8 induces polyfunctional B lymphocytes that drive Kaposi's sarcoma by Knowlton, Emilee R, Rappocciolo, Giovanna, Piazza, Paolo, Lepone, Lauren M, Nadgir, Sagar V, Bullotta, Arlene, Berendam, Stella J, Li, Jun, Reinhart, Todd A, Jenkins, Frank J, Rinaldo, Charles R

“…Kaposi's sarcoma (KS) is an unusual neoplasia wherein the tumor consists primarily of endothelial cells infected with human herpesvirus 8 (HHV-8; Kaposi's…”
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Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells by COLLETON, Bonnie A, HUANG, Xiao-Li, MELHEM, Nada M, ZHENG FAN, BOROWSKI, Luann, RAPPOCCIOLO, Giovanna, RINALDO, Charles R

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Human herpesvirus 8 replicates in primary B lymphocytes and induces polyfunctional cytokine and chemokine responses by Knowlton, Emilee, Rappocciolo, Giovanna, Jenkins, Frank J, Jais, Mariel, Piazza, Paolo, Rinaldo, Charles R

“…Doc number: P36…”
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Inefficient HIV-1 trans infection of CD4 + T cells by macrophages from HIV-1 nonprogressors is associated with altered membrane cholesterol and DC-SIGN by DeLucia, Diana C, Rinaldo, Charles R, Rappocciolo, Giovanna

“…Professional antigen presenting cells (APC: myeloid dendritic cells (DC) and macrophages (MΦ); B lymphocytes) mediate highly efficient HIV-1 infection of CD4 T…”
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Correction: DC-SIGN on B Lymphocytes Is Required for Transmission of HIV-1 to T Lymphocytes by Rappocciolo, Giovanna, Piazza, Paolo, Fuller, Craig L., Reinhart, Todd A., Watkins, Simon C., Rowe, David T., Jais, Mariel, Gupta, Phalguni, Rinaldo, Charles R.

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Human Herpesvirus 8 Infects and Replicates in Langerhans Cells and Interstitial Dermal Dendritic Cells and Impairs Their Function by Rappocciolo, Giovanna, Jais, Mariel, Piazza, Paolo A, DeLucia, Diana C, Jenkins, Frank J, Rinaldo, Charles R

“…The predominant types of dendritic cells (DC) in the skin and mucosa are Langerhans cells (LC) and interstitial dermal DC (iDDC). LC and iDDC process cutaneous…”
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Effect of Statin Use on Inflammation and Immune Activation Biomarkers in HIV-Infected Persons on Effective Antiretroviral Therapy by Hussain, Shehnaz K, Golozar, Asieh, Widney, Daniel P, Rappocciolo, Giovanna, Penugonda, Sudhir, Bream, Jay H, Martínez-Maza, Otoniel, Jacobson, Lisa P

“…Immune activation and inflammation are hallmarks of chronic HIV infection and are etiologically linked to major causes of morbidity and mortality among…”
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Comment on primary lymphocyte infection models for KSHV and its putative tumorigenesis mechanisms in B cell lymphomas (Journal of Microbiology 2017, 55(5): 319-329) by Rappocciolo, Giovanna, Jenkins, Frank, Rinaldo, Charles R.

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Multiplex assay reliability and long-term intra-individual variation of serologic inflammatory biomarkers by McKay, Heather S., Margolick, Joseph B., Martínez-Maza, Otoniel, Lopez, Joseph, Phair, John, Rappocciolo, Giovanna, Denny, Thomas N., Magpantay, Larry I., Jacobson, Lisa P., Bream, Jay H.

“…•CCLL, CCL2, CCL13, and CCL4 exhibit strong within-person tracking up to 15 years apart.•CXCL13 exhibits strong tracking only up to 8 years between…”
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Human herpesvirus 8 glycoprotein B binds the entry receptor DC-SIGN by Hensler, Heather R., Tomaszewski, Monica J., Rappocciolo, Giovanna, Rinaldo, Charles R., Jenkins, Frank J.

“…•Glycoprotein B (gB) of human herpesvirus 8 (HHV-8) has a high mannose carbohydrate structure.•The HHV-8 gB protein binds to the viral entry receptor,…”
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CD4 T regulatory cells (Treg) control CD8 T cell responses to human herpesvirus 8 (HHV-8) lytic and latency proteins (P6056) by Lepone, Lauren, Rappocciolo, Giovanna, Knowlton, Emilee, Jenkins, Frank, Rinaldo, Charles

“…Abstract Although CD8 T cells are considered important in controlling HHV-8 (aka KSHV) infection, the etiologic agent of Kaposi’s sarcoma (KS), there is little…”
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Efficient HIV-1 Trans Infection of CD4+ T Cells Occurs in the Presence of Antiretroviral Therapy by Rappocciolo, Giovanna, Sluis-Cremer, Nicolas, Rinaldo, Charles R

“…Abstract Background Antiretroviral therapy (ART) has dramatically improved the quality of life of people with HIV-1 infection (PWH). However, it is not…”
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