Search Results - "Rapp, Nikolas"
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Calcium Signalling in Heart and Vessels: Role of Calmodulin and Downstream Calmodulin-Dependent Protein Kinases
Published in International journal of molecular sciences (17-12-2022)“…Cardiovascular disease is the major cause of death worldwide. The success of medication and other preventive measures introduced in the last century have not…”
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Uremic Toxins and Vascular Calcification-Missing the Forest for All the Trees
Published in Toxins (29-09-2020)“…The cardiorenal syndrome relates to the detrimental interplay between the vascular system and the kidney. The uremic milieu induced by reduced kidney function…”
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Hepatic and Vascular Vitamin K Status in Patients with High Cardiovascular Risk
Published in Nutrients (01-10-2021)“…Vitamin K dependent proteins (VKDP), such as hepatic coagulation factors and vascular matrix Gla protein (MGP), play key roles in maintaining physiological…”
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Menaquinone-7 Supplementation Improves Osteogenesis in Pluripotent Stem Cell Derived Mesenchymal Stem Cells
Published in Frontiers in cell and developmental biology (28-01-2021)“…Development of clinical stem cell interventions are hampered by immature cell progeny under current protocols. Human mesenchymal stem cells (hMSCs) are…”
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Altered vitamin K biodistribution and metabolism in experimental and human chronic kidney disease
Published in Kidney international (01-02-2022)“…Chronic kidney disease (CKD) is accompanied with extensive cardiovascular calcification, in part correlating with functional vitamin K deficiency. Here, we…”
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The BioHybrid Assay: A Novel Method for Determining Calcification Propensity
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Vascular calcification is an active pathological process, characterised by cellular dysregulation and subsequent changes to the extracellular environment. In…”
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