Search Results - "Raposo, G"

The complex ultrastructure of the endolysosomal system by Klumperman, Judith, Raposo, Graça

“…Live-cell imaging reveals the endolysosomal system as a complex and highly dynamic network of interacting compartments. Distinct types of endosomes are…”
Get full text

ZNF330/NOA36 interacts with HSPA1 and HSPA8 and modulates cell cycle and proliferation in response to heat shock in HEK293 cells by Sanchez-Briñas, Alejandra, Duran-Ruiz, Carmen, Astola, Antonio, Arroyo, Marta Marina, Raposo, Fátima G, Valle, Antonio, Bolivar, Jorge

“…The human genome contains nearly 20.000 protein-coding genes, but there are still more than 6,000 proteins poorly characterized. Among them, ZNF330/NOA36 stand…”
Get full text

Exosomes are released by cultured cortical neurones by Fauré, J., Lachenal, G., Court, M., Hirrlinger, J., Chatellard-Causse, C., Blot, B., Grange, J., Schoehn, G., Goldberg, Y., Boyer, V., Kirchhoff, F., Raposo, G., Garin, J., Sadoul, R.

“…Accumulating evidence shows that several cell types have the capacity to secrete membrane proteins by incorporating them into exosomes, which are small lipid…”
Get full text

Proteomic Analysis of Dendritic Cell-Derived Exosomes: A Secreted Subcellular Compartment Distinct from Apoptotic Vesicles by Thery, Clotilde, Boussac, Muriel, Veron, Philippe, Ricciardi-Castagnoli, Paola, Raposo, Graca, Garin, Jerome, Amigorena, Sebastian

“…Dendritic cells constitutively secrete a population of small (50-90 nm diameter) Ag-presenting vesicles called exosomes. When sensitized with tumor antigenic…”
Get full text

A novel dendritic cell subset involved in tumor immunosurveillance by Zitvogel, Laurence, Taieb, Julien, Chaput, Nathalie, Ménard, Cédric, Apetoh, Lionel, Ullrich, Evelyn, Bonmort, Mathieu, Péquignot, Marie, Casares, Noelia, Terme, Magali, Flament, Caroline, Opolon, Paule, Lecluse, Yann, Métivier, Didier, Tomasello, Elena, Vivier, Eric, Ghiringhelli, François, Martin, François, Klatzmann, David, Poynard, Thierry, Tursz, Thomas, Raposo, Graça, Yagita, Hideo, Ryffel, Bernard, Kroemer, Guido

“…The interferon (IFN)-γ-induced TRAIL effector mechanism is a vital component of cancer immunosurveillance by natural killer (NK) cells in mice. Here we show…”
Get full text

Development and Application of a Mechanistic Nutrient-Based Model for Precision Fish Farming by Soares, Filipe M. R. C, Nobre, Ana M. D, Raposo, Andreia I. G, Mendes, Rodrigo C. P, Engrola, Sofia A. D, Rema, Paulo J. A. P, Conceição, Luís E. C, Silva, Tomé S

“…This manuscript describes and evaluates the FEEDNETICS model, a detailed mechanistic nutrient-based model that has been developed to be used as a data…”
Get full text

Pmel17 initiates premelanosome morphogenesis within multivesicular bodies by Berson, J F, Harper, D C, Tenza, D, Raposo, G, Marks, M S

“…Melanosomes are tissue-specific organelles within which melanin is synthesized and stored. The melanocyte-specific glycoprotein Pmel17 is enriched in the lumen…”
Get full text

B lymphocytes secrete antigen-presenting vesicles by Raposo, G, Nijman, H W, Stoorvogel, W, Liejendekker, R, Harding, C V, Melief, C J, Geuze, H J

“…Antigen-presenting cells contain a specialized late endocytic compartment, MIIC (major histocompatibility complex [MHC] class II-enriched compartment), that…”
Get full text

Tumor-derived exosomes: a new source of tumor rejection antigens by André, F, Schartz, N.E.C, Chaput, N, Flament, C, Raposo, G, Amigorena, S, Angevin, E, Zitvogel, L

“…Exosomes are small vesicles released by a broad array of hematopoietic cells. Previous studies showed that exosomes released by antigen loaded dendritic cells…”
Get full text

Caveolae and sorting in the trans‐Golgi network of epithelial cells by Dupree, P., Parton, R.G., Raposo, G., Kurzchalia, T.V., Simons, K.

“…VIP21 is a 21 kDa membrane protein present in TGN‐derived transport vesicles isolated from the epithelial MDCK cell line. The membrane topology and subcellular…”
Get full text

Truncated Brush Border Myosin I Affects Membrane Traffic in Polarized Epithelial Cells by Durrbach, A., Raposo, G., Tenza, D., Louvard, D., Coudrier, E.

“…We investigate, in this study, the potential involvement of an acto‐myosin‐driven mechanism in endocytosis of polarized cells. We observed that…”
Get full text

Exosomes: endosomal-derived vesicles shipping extracellular messages by Février, Benoit, Raposo, Graça

“…Exosomes are membrane vesicles released into the extracellular environment upon exocytic fusion of multivesicular endosomes with the cell surface. They have a…”
Get full text

Association of Engrailed homeoproteins with vesicles presenting caveolae-like properties by Joliot, A, Trembleau, A, Raposo, G, Calvet, S, Volovitch, M, Prochiantz, A

“…We report here that the homeoproteins Engrailed-1 and Engrailed-2 are present in specific non-nuclear subcellular compartments. Using electron microscopy, we…”
Get full text

How MHC class II molecules reach the endocytic pathway by Bénaroch, P., Yilla, M., Raposo, G., Ito, K., Miwa, K., Geuze, H.J., Ploegh, H.L.

“…We have examined trafficking of major histocompatibility complex (MHC) class II molecules in human B cells exposed to concanamycin B, a highly specific…”
Get full text

Misfolded Major Histocompatibility Complex Class I Molecules Accumulate in an Expanded ER-Golgi Intermediate Compartment by Raposo, Graça, van Santen, Hisse Martien, Leijendekker, Richtje, Geuze, Hans J., Ploegh, Hidde L.

“…Misfolded membrane proteins are rapidly degraded, often shortly after their synthesis and insertion in the endoplasmic reticulum (ER), but the exact location…”
Get full text

Dendritic cells or their exosomes are effective biotherapies of cancer by Zitvogel, L, Fernandez, N, Lozier, A, Wolfers, J, Regnault, A, Raposo, G, Amigorena, S

Get full text

516 Dynein is involved in the movement, distribution, acidity, and transfer of melanosomes by Aktary, Z., Amblard, F., Raposo, G., Delevoye, C., Coscoy, S., Larue, L.

Get full text

Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes by Peters, P J, Raposo, G, Neefjes, J J, Oorschot, V, Leijendekker, R L, Geuze, H J, Ploegh, H L

“…In human B lymphoblastoid cell lines, the majority of major histocompatibility complex (MHC) class II heterodimers are located on the cell surface and in…”
Get full text

The power of imaging to understand extracellular vesicle biology in vivo by Verweij, Frederik J., Balaj, Leonora, Boulanger, Chantal M., Carter, David R. F., Compeer, Ewoud B., D’Angelo, Gisela, El Andaloussi, Samir, Goetz, Jacky G., Gross, Julia Christina, Hyenne, Vincent, Krämer-Albers, Eva-Maria, Lai, Charles P., Loyer, Xavier, Marki, Alex, Momma, Stefan, Nolte-‘t Hoen, Esther N. M., Pegtel, D. Michiel, Peinado, Hector, Raposo, Graça, Rilla, Kirsi, Tahara, Hidetoshi, Théry, Clotilde, van Royen, Martin E., Vandenbroucke, Roosmarijn E., Wehman, Ann M., Witwer, Kenneth, Wu, Zhiwei, Wubbolts, Richard, van Niel, Guillaume

“…Extracellular vesicles (EVs) are nano-sized lipid bilayer vesicles released by virtually every cell type. EVs have diverse biological activities, ranging from…”
Get full text

Evidence-Based Clinical Use of Nanoscale Extracellular Vesicles in Nanomedicine by Fais, Stefano, O’Driscoll, Lorraine, Borras, Francesc E, Buzas, Edit, Camussi, Giovanni, Cappello, Francesco, Carvalho, Joana, Cordeiro da Silva, Anabela, Del Portillo, Hernando, El Andaloussi, Samir, Ficko Trček, Tanja, Furlan, Roberto, Hendrix, An, Gursel, Ihsan, Kralj-Iglic, Veronika, Kaeffer, Bertrand, Kosanovic, Maja, Lekka, Marilena E, Lipps, Georg, Logozzi, Mariantonia, Marcilla, Antonio, Sammar, Marei, Llorente, Alicia, Nazarenko, Irina, Oliveira, Carla, Pocsfalvi, Gabriella, Rajendran, Lawrence, Raposo, Graça, Rohde, Eva, Siljander, Pia, van Niel, Guillaume, Vasconcelos, M. Helena, Yáñez-Mó, María, Yliperttula, Marjo L, Zarovni, Natasa, Zavec, Apolonija Bedina, Giebel, Bernd

“…Recent research has demonstrated that all body fluids assessed contain substantial amounts of vesicles that range in size from 30 to 1000 nm and that are…”
Get full text