Search Results - "Rapizzi, E."
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Testosterone treatment is associated with reduced adipose tissue dysfunction and nonalcoholic fatty liver disease in obese hypogonadal men
Published in Journal of endocrinological investigation (01-04-2021)“…Purpose In both preclinical and clinical settings, testosterone treatment (TTh) of hypogonadism has shown beneficial effects on insulin sensitivity and…”
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A unique neuroendocrine cell model derived from the human foetal neural crest
Published in Journal of endocrinological investigation (01-09-2020)“…Purpose Nowadays, no human neuroendocrine cell models derived from the neural crest are available. In this study, we present non-transformed long-term primary…”
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Mitochondrial function and content in pheochromocytoma/paraganglioma of succinate dehydrogenase mutation carriers
Published in Endocrine-related cancer (01-06-2012)“…To date, the consequences of succinate dehydrogenase (SDH) impairment on overall mitochondrial functions are still obscure. In this study, we evaluated SDH…”
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Recombinant aequorin and green fluorescent protein as valuable tools in the study of cell signalling
Published in Biochemical journal (01-04-2001)“…Luminous proteins include primary light producers, such as aequorin, and secondary photoproteins that in some organisms red-shift light emission for better…”
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Clinical relevance of phenotype/genotype correlations in the diagnosis and therapy of pheochromocytomas/paragangliomas
Published in The quarterly journal of nuclear medicine and molecular imaging (01-06-2013)“…Pheochromocytomas and paragangliomas are tumors arising from neural crest-derived cells. They can be sympathetic in origin, catecholamine secreting and located…”
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Intravitreal bevacizumab therapy for choroidal neovascularization secondary to age-related macular degeneration: 6-month results of an open-label uncontrolled clinical study
Published in European journal of ophthalmology (01-03-2007)“…To investigate the 6-month safety and clinical outcomes of intravitreal injections of bevacizumab administered to treat choroidal neovascularization secondary…”
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Anti-ribosomal P protein antibodies detected by immunoblotting in patients with connective tissue diseases: their specificity for SLE and association with IgG anticardiolipin antibodies
Published in Annals of the rheumatic diseases (01-12-2000)“…OBJECTIVE To assess the prevalence and clinical and serological associations of anti-ribosomal P protein antibodies (anti-P antibodies) in patients with…”
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ED2+ Macrophages Increase Selectively Myoblast Proliferation in Muscle Cultures
Published in Biochemical and biophysical research communications (27-06-1997)“…We have previously shown by coculturing myoblasts and macrophages that myotube formation is strongly increased in vitro by the presence of an acid stable,…”
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Transpupillary thermotherapy in the management of circumscribed choroidal hemangioma
Published in American journal of ophthalmology (01-04-1999)“…Purpose: To report a case of circumscribed choroidal hemangioma effectively managed with transpupillary thermotherapy. Method: A 53-year-old man affected by…”
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Human Satellite Cell-Proliferation in Vitro Is Regulated by Autocrine Secretion of IL-6 Stimulated by a Soluble Factor(s) Released by Activated Monocytes
Published in Biochemical and biophysical research communications (02-11-1995)“…We previously showed that macrophages, besides their scavenger role, selectively induce rat myoblast proliferation in vitro by releasing soluble factors. In…”
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Clear corneal incision of 2.75 mm for cataract surgery induces little change of astigmatism in eyes with low preoperative corneal cylinder
Published in European journal of ophthalmology (01-05-2006)“…To assess the early astigmatic effect induced by 2.75 mm clear cornea incisions with different locations for cataract surgery. A total of 146 eyes of different…”
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(082) The Effect of Sex Steroids on RhoA/ROCK Pathway in Rat Distal Vagina
Published in Journal of sexual medicine (22-05-2023)“…Abstract Introduction The RhoA/ROCK calcium-sensitizing pathway plays a role in clitoral contractility, and therefore we deemed interesting to investigate its…”
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Distal Vagina Smooth Muscle Contractility Mechanisms: Effects of in Vivo Sex Steroids Treatment in an Animal Experimental Model of Ovariectomy
Published in Journal of sexual medicine (01-08-2022)“…Female sexual response is a complex phenomenon that involves multiple psychophysiological factors. Sex steroids play a fundamental role in the mechanisms of…”
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Antiphospholipid antibody syndrome and polymyalgia rheumatica/giant cell arteritis
Published in Rheumatology (Oxford, England) (01-05-2000)Get full text
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The Ca2+ concentration of the endoplasmic reticulum is a key determinant of ceramide-induced apoptosis: significance for the molecular mechanism of Bcl-2 action
Published in The EMBO journal (01-06-2001)“…The mechanism of action of the anti‐apoptotic oncogene Bcl‐2 is still largely obscure. We have recently shown that the overexpression of Bcl‐2 in HeLa cells…”
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Outcome of fifty-five newborns of antiphospholipid antibody-positive mothers treated with calcium heparin during pregnancy
Published in Clinical and experimental rheumatology (01-09-1998)“…The outcome of 55 infants born to 53 antiphospholipid antibody (aPL)-positive mothers treated during pregnancy with calcium heparin is described. The clinical…”
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Nuclear Poly(ADP-ribose) Polymerase-1 Rapidly Triggers Mitochondrial Dysfunction
Published in The Journal of biological chemistry (29-04-2005)“…To obtain further information on time course and mechanisms of cell death after poly(ADP-ribose) polymerase-1 (PARP-1) hyperactivation, we used HeLa cells…”
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Recombinant Expression of the Voltage-Dependent Anion Channel Enhances the Transfer of Ca2+ Microdomains to Mitochondria
Published in The Journal of cell biology (25-11-2002)“…Although the physiological relevance of mitochondrial Ca2+ homeostasis is widely accepted, no information is yet available on the molecular identity of the…”
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Yeast model for evaluating the pathogenic significance of SDHB, SDHC and SDHD mutations in PHEO-PGL syndrome
Published in Human molecular genetics (15-02-2013)“…SDH genes, encoding succinate dehydrogenase, act as tumour suppressor genes, linking mitochondrial dysfunction with tumourigenesis. Heterozygous germline…”
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