Search Results - "Raouf, A"

Biochemical and Biological Attributes of Matrix Metalloproteinases by Cui, Ning, Hu, Min, Khalil, Raouf A

“…Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that are involved in the degradation of various proteins in the extracellular…”
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Evolving mechanisms of vascular smooth muscle contraction highlight key targets in vascular disease by Liu, Zhongwei, Khalil, Raouf A.

“…[Display omitted] Vascular smooth muscle (VSM) plays an important role in the regulation of vascular function. Identifying the mechanisms of VSM contraction…”
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Assessment of breaking waves and liquid sloshing impact by Ibrahim, Raouf A.

“…This article presents an overview of breaking waves and liquid sloshing impact acting on rigid walls and in liquid containers. The physics of breaking waves…”
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Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia by Chen, Juanjuan, Khalil, Raouf A

“…Normal pregnancy is associated with marked hemodynamic and uterine changes that allow adequate uteroplacental blood flow and uterine expansion for the growing…”
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Estrogen, vascular estrogen receptor and hormone therapy in postmenopausal vascular disease by Khalil, Raouf A.

“…Cardiovascular disease (CVD) is less common in premenopausal women than men of the same age or postmenopausal women, suggesting vascular benefits of estrogen…”
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A Disintegrin and Metalloproteinase (ADAM) and ADAM with thrombospondin motifs (ADAMTS) family in vascular biology and disease by Zhong, Sheng, Khalil, Raouf A.

“…[Display omitted] A Disintegrin and Metalloproteinase (ADAM) is a family of proteolytic enzymes that possess sheddase function and regulate shedding of…”
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Inflammatory cytokines in vascular dysfunction and vascular disease by Sprague, Alexander H., Khalil, Raouf A.

“…The vascular inflammatory response involves complex interaction between inflammatory cells (neutrophils, lymphocytes, monocytes, macrophages), endothelial…”
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Mechanisms of pulmonary vascular dysfunction in pulmonary hypertension and implications for novel therapies by Christou, Helen, Khalil, Raouf A

“…Pulmonary hypertension (PH) is a serious disease characterized by various degrees of pulmonary vasoconstriction and progressive fibroproliferative remodeling…”
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Emerging mechanisms in the pathogenesis of hypertension by Khalil, Raouf A.

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Matrix Metalloproteinase Inhibitors as Investigational and Therapeutic Tools in Unrestrained Tissue Remodeling and Pathological Disorders by Liu, Jie, Khalil, Raouf A

“…Matrix metalloproteinases (MMPs) are zinc-dependent proteolytic enzymes that degrade various proteins in the extracellular matrix (ECM). MMPs may also regulate…”
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Role of ADAM and ADAMTS disintegrin and metalloproteinases in normal pregnancy and preeclampsia by Qu, Hongmei, Khalil, Raouf A.

“…[Display omitted] Normal pregnancy (NP) involves intricate processes starting with egg fertilization, proceeding to embryo implantation, placentation and…”
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Matrix Metalloproteinases as Regulators of Vein Structure and Function: Implications in Chronic Venous Disease by MacColl, Elisabeth, Khalil, Raouf A

“…Lower-extremity veins have efficient wall structure and function and competent valves that permit upward movement of deoxygenated blood toward the heart…”
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Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsia by Shah, Dania A., Khalil, Raouf A.

“…Preeclampsia is a pregnancy-associated disorder characterized by hypertension, and could lead to maternal and fetal morbidity and mortality; however, the…”
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Matrix metalloproteinases as potential targets in the venous dilation associated with varicose veins by Kucukguven, Arda, Khalil, Raouf A

“…Varicose veins (VVs) are a common venous disease of the lower extremity characterized by incompetent valves, venous reflux, and dilated and tortuous veins. If…”
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MMPs and ADAMs/ADAMTS inhibition therapy of abdominal aortic aneurysm by Li, Yongqi, Wang, Weicheng, Li, Lei, Khalil, Raouf A.

“…Abdominal aortic aneurysm (AAA) is a chronic vascular degenerative disease featured by progressive dilation and remodeling of the vascular wall, which may lead…”
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Why Venous Leg Ulcers Have Difficulty Healing: Overview on Pathophysiology, Clinical Consequences, and Treatment by Raffetto, Joseph D, Ligi, Daniela, Maniscalco, Rosanna, Khalil, Raouf A, Mannello, Ferdinando

“…Venous leg ulcers (VLUs) are one of the most common ulcers of the lower extremity. VLU affects many individuals worldwide, could pose a significant…”
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Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn by Majed, Batoule H, Khalil, Raouf A

“…Prostacyclin (PGI(2)) is a member of the prostanoid group of eicosanoids that regulate homeostasis, hemostasis, smooth muscle function and inflammation…”
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Vascular endothelin receptor type B: Structure, function and dysregulation in vascular disease by Mazzuca, Marc Q., Khalil, Raouf A.

“…Endothelin-1 (ET-1) is a major regulator of vascular function, acting via both endothelin receptor type A (ETAR) and type B (ETBR). Although the role of ETAR…”
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Zymography as a Research Tool in the Study of Matrix Metalloproteinase Inhibitors by Ren, Zongli, Chen, Juanjuan, Khalil, Raouf A

“…Matrix metalloproteinases (MMPs) are proteolytic enzymes that degrade various components of the extracellular matrix (ECM) and play a role in tissue…”
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Regulation of vascular angiotensin II type 1 and type 2 receptor and angiotensin-(1-7)/MasR signaling in normal and hypertensive pregnancy by Clark, Caroline R, Khalil, Raouf A

“…Normal pregnancy (Norm-Preg) is associated with a slight reduction in blood pressure (BP) and decreased BP response to vasoconstrictor stimuli such as…”
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