Search Results - "Rao, Yu"

A Review of Recent Investigations on Flow and Heat Transfer Enhancement in Cooling Channels Embedded with Triply Periodic Minimal Surfaces (TPMS) by Yeranee, Kirttayoth, Rao, Yu

“…Triply periodic minimal surfaces (TPMS) have shown better mechanical performance, mass transfer, and thermal conductivity than conventional and strut-based…”
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PROTAC Technology: Opportunities and Challenges by Gao, Hongying, Sun, Xiuyun, Rao, Yu

“…PROTACs-induced targeted protein degradation has emerged as a novel therapeutic strategy in drug development and attracted the favor of academic institutions,…”
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Optimization of the hole distribution of an effusively cooled surface facing non-uniform incoming temperature using deep learning approaches by Yang, Li, Dai, Wei, Rao, Yu, Chyu, Minking K.

“…•This study utilizes the image-to-image concept for optimization.•The cGAN model successfully reconstructed the 2-D distribution of η.•The deep learning model…”
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Regio- and Chemoselective CH Chlorination/Bromination of Electron-Deficient Arenes by Weak Coordination and Study of Relative Directing-Group Abilities by Sun, Xiuyun, Shan, Gang, Sun, Yonghui, Rao, Yu

“…It's all relative: A practical and efficient PdII‐catalyzed regio‐ and chemoselective chlorination/bromination has been developed for the facile synthesis of a…”
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Enhanced thermal performance of a pin-fin cooling channel for gas turbine blade by density-based topology optimization by Yeranee, Kirttayoth, Rao, Yu, Yang, Li, Li, Hao

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Privacy Techniques for Edge Computing Systems by Rao, Fang-Yu, Bertino, Elisa

“…In an edge-enabled data management and computing environment, it is critical to ensure the privacy of the information acquired, processed, and exchanged among…”
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Weak Coordination Promoted Regioselective Oxidative Coupling Reaction for 2,2′-Difunctional Biaryl Synthesis in Hexafluoro-2-propanol by Zhang, Chao, Rao, Yu

“…An unprecedented weak coordination promoted dehydrogenative cross-coupling reaction has been developed by palladium catalysis, which provides a convenient…”
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Experimental Study of Heat Transfer and Pressure Loss in Channels with Miniature V Rib-Dimple Hybrid Structure by Rao, Yu, Zhang, Peng

“…In order to increase the thermal efficiency, the gas turbines are designed to operate at higher temperature, which requires highly efficient cooling structures…”
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A lever-like transduction pathway for long-distance chemical- and mechano-gating of the mechanosensitive Piezo1 channel by Wang, Yanfeng, Chi, Shaopeng, Guo, Huifang, Li, Guang, Wang, Li, Zhao, Qiancheng, Rao, Yu, Zu, Liansuo, He, Wei, Xiao, Bailong

“…Piezo1 represents a prototype of eukaryotic mechanotransduction channels. The full-length 2547-residue mouse Piezo1 possesses a unique 38-transmembrane-helix…”
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PROTACs: great opportunities for academia and industry by Sun, Xiuyun, Gao, Hongying, Yang, Yiqing, He, Ming, Wu, Yue, Song, Yugang, Tong, Yan, Rao, Yu

“…Although many kinds of therapies are applied in the clinic, drug-resistance is a major and unavoidable problem. Another disturbing statistic is the limited…”
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Global PROTAC Toolbox for Degrading BCR–ABL Overcomes Drug-Resistant Mutants and Adverse Effects by Yang, Yiqing, Gao, Hongying, Sun, Xiuyun, Sun, Yonghui, Qiu, Yueping, Weng, Qinjie, Rao, Yu

“…The BCR–ABL fusion oncoprotein causes chronic myeloid leukemia or acute lymphoblastic leukemia in Ph+ patients because the ABL kinase is constitutively…”
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Developing potent PROTACs tools for selective degradation of HDAC6 protein by An, Zixuan, Lv, Wenxing, Su, Shang, Wu, Wei, Rao, Yu

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Numerical predictions of jet impingement heat transfer on square pin-fin roughened plates by Wan, Chaoyi, Rao, Yu, Chen, Peng

“…A comparative numerical study has been conducted on the heat transfer characteristics of an array of jet impingement on a flat plate and plates roughened with…”
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Crystal structure of a bacterial homologue of glucose transporters GLUT1–4 by Sun, Linfeng, Zeng, Xin, Yan, Chuangye, Sun, Xiuyun, Gong, Xinqi, Rao, Yu, Yan, Nieng

“…Glucose transporters are essential for metabolism of glucose in cells of diverse organisms from microbes to humans, exemplified by the disease-related human…”
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Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders by Su, Shang, Yang, Zimo, Gao, Hongying, Yang, Haiyan, Zhu, Songbiao, An, Zixuan, Wang, Juanjuan, Li, Qing, Chandarlapaty, Sarat, Deng, Haiteng, Wu, Wei, Rao, Yu

“…A focused PROTAC library hijacking cancer therapeutic target CDK6 was developed. A design principle as “match/mismatch” was proposed for understanding the…”
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Synthesis of 2‑Aminophenols and Heterocycles by Ru-Catalyzed C–H Mono- and Dihydroxylation by Yang, Xinglin, Shan, Gang, Rao, Yu

“…A novel and efficient synthesis of 2-aminophenols, 2-aminobenzene-1,3-diols, and heterocycles through Ru-catalyzed C–H mono- and dihydroxylation of anilides…”
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On the Security of a Variant of ElGamal Encryption Scheme by Rao, Fang-Yu

“…Recently, based on the Paillier cryptosystem [1] , Yi et al. outline a distributed ElGamal cryptosystem which allows for both a much simpler distributed key…”
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Development of a Rhodium(II)-Catalyzed Chemoselective C(sp3)H Oxygenation by Lin, Yun, Zhu, Lei, Lan, Yu, Rao, Yu

“…We report the first example of RhII‐catalyzed chemoselective double C(sp3)H oxygenation, which can directly transform various toluene derivatives into highly…”
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PROTACs: great opportunities for academia and industry (an update from 2020 to 2021) by He, Ming, Cao, Chaoguo, Ni, Zhihao, Liu, Yongbo, Song, Peilu, Hao, Shuang, He, Yuna, Sun, Xiuyun, Rao, Yu

“…PROteolysis TArgeting Chimeras (PROTACs) technology is a new protein-degradation strategy that has emerged in recent years. It uses bifunctional small…”
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Pd(II) catalyzed ortho C-H iodination of phenylcarbamates at room temperature using cyclic hypervalent iodine reagents by Sun, Xiuyun, Yao, Xia, Zhang, Chao, Rao, Yu

“…A novel approach to access ortho iodinated phenols using cyclic hypervalent iodine reagents through palladium(II) catalyzed C-H activation has been developed…”
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