Search Results - "Rao, Yathindar S."
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1
Differential Effects of E2 on MAPK Activity in the Brain and Heart of Aged Female Rats
Published in PloS one (03-08-2016)“…Aging and the coincident loss of circulating estrogens at menopause lead to increased risks for neurological and cardiovascular pathologies. Clinical studies…”
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Journal Article -
2
Long-term effects of peripubertal binge EtOH exposure on hippocampal microRNA expression in the rat
Published in PloS one (08-01-2014)“…Adolescent binge alcohol abuse induces long-term changes in gene expression, which impacts the physiological stress response and memory formation, two…”
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Journal Article -
3
Parental binge alcohol abuse alters F1 generation hypothalamic gene expression in the absence of direct fetal alcohol exposure
Published in PloS one (20-02-2014)“…Adolescent binge alcohol exposure has long-lasting effects on the expression of hypothalamic genes that regulate the stress response, even in the absence of…”
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Journal Article -
4
Effects of kisspeptin on parameters of the HPA axis
Published in Endocrine (01-06-2011)“…The hypothalamo–pituitary–adrenal (HPA) and hypothalamo–pituitary–gonadal (HPG) axes have an intricate cross talk that results in the inhibition of…”
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Journal Article -
5
microRNA Expression Profiles in the Ventral Hippocampus during Pubertal Development and the Impact of Peri-Pubertal Binge Alcohol Exposure
Published in Non-coding RNA (05-03-2019)“…Adolescence is hallmarked by two parallel processes of sexual maturation and adult patterning of the brain. Therefore, adolescence represents a vulnerable…”
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6
microRNAs and the adolescent brain: Filling the knowledge gap
Published in Neuroscience and biobehavioral reviews (01-11-2016)“…•This review gives a brief summary of miRNA biogenesis and function in the brain.•The impact of hormones on miRNA function are discussed.•MiRNA function during…”
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7
Aging and Loss of Circulating 17β-Estradiol Alters the Alternative Splicing of ERβ in the Female Rat Brain
Published in Endocrinology (Philadelphia) (01-11-2015)“…Loss of circulating 17β-estradiol (E2) that occurs during menopause can have detrimental effects on cognitive function. The efficacy of hormone replacement…”
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8
MicroRNAs in the Aging Female Brain: A Putative Mechanism for Age-Specific Estrogen Effects
Published in Endocrinology (Philadelphia) (01-08-2013)“…Menopause is characterized by the rapid age-related decline of circulating 17β-estradiol (E2) levels in women, which can sometimes result in cognitive…”
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9
Prolonged ovarian hormone deprivation alters the effects of 17β-estradiol on microRNA expression in the aged female rat hypothalamus
Published in Oncotarget (10-11-2015)“…Administration of 17β-estradiol (E2) has beneficial effects on cognitive function in peri- but not post-menopausal women, yet the molecular mechanisms…”
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10
17β-estradiol regulates the RNA-binding protein Nova1, which then regulates the alternative splicing of estrogen receptor β in the aging female rat brain
Published in Neurobiology of aging (01-01-2018)“…Alternative RNA splicing results in the translation of diverse protein products arising from a common nucleotide sequence. These alternative protein products…”
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11
An emerging role for microRNAs in sexually dimorphic neurobiological systems
Published in Pflügers Archiv (01-05-2013)“…Over the past 20 years, our understanding of the basic mechanisms of gene regulation has vastly expanded due to the unexpected roles of small regulatory RNAs,…”
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12
Binge-pattern alcohol exposure during puberty induces sexually dimorphic changes in genes regulating the HPA axis
Published in American journal of physiology: endocrinology and metabolism (01-02-2010)“…Maternal alcohol consumption during critical periods of fetal brain development leads to devastating long-term consequences on adult reproductive physiology,…”
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13
Age-dependent Effects of 17β-estradiol on the Dynamics of Estrogen Receptor β (ERβ) Protein–Protein Interactions in the Ventral Hippocampus
Published in Molecular & cellular proteomics (01-03-2014)“…Recent clinical evidence suggests that the neuroprotective and beneficial effects of hormone therapy may be limited by factors related to age and reproductive…”
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14
Phosphorylation alters Oestrogen Receptor β-mediated transcription in neurons
Published in Journal of neuroendocrinology (01-12-2015)“…Nuclear steroid hormone receptors are ubiquitously expressed transcription factors whose activity can be altered by post-translational modifications, such as…”
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15
Regulation of micrornas by 17β-estradiol in the aging female brain
Published 01-01-2015“…Hormone Therapy (HT) is used to increase the 17β-estradiol (E2) levels in women who are going through the menopausal transition to alleviate the negative…”
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Dissertation -
16
Parental Binge Alcohol Abuse Alters F1 Generation Hypothalamic Gene Expression in the Absence of Direct Fetal Alcohol Exposure: e89320
Published in PloS one (01-02-2014)“…Adolescent binge alcohol exposure has long-lasting effects on the expression of hypothalamic genes that regulate the stress response, even in the absence of…”
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Journal Article -
17
Regulation of micrornas by 17beta-estradiol in the aging female brain
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Dissertation