Search Results - "Rao, Vasudev R."

HIV-1 Induced CNS Dysfunction: Current Overview and Research Priorities by Joseph, Jeymohan, Colosi, Deborah A, Rao, Vasudev R

“…Over the past three decades, the clinical presentation of HIV infection of the Central Nervous System (CNS) has evolved. Prior to wide spread use of effective…”
Get more information

CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release by Ajasin, David O, Rao, Vasudev R, Wu, Xuhong, Ramasamy, Santhamani, Pujato, Mario, Ruiz, Arthur P, Fiser, Andras, Bresnick, Anne R, Kalpana, Ganjam V, Prasad, Vinayaka R

“…Cellular ESCRT machinery plays pivotal role in HIV-1 budding and release. Extracellular stimuli that modulate HIV-1 egress are currently unknown. We found that…”
Get full text

HIV-1 Clade-Specific Differences in the Induction of Neuropathogenesis by Rao, Vasudev R, Sas, Andrew R, Eugenin, Eliseo A, Siddappa, Nagadenahalli B, Bimonte-Nelson, Heather, Berman, Joan W, Ranga, Udaykumar, Tyor, William R, Prasad, Vinayaka R

“…Human immunodeficiency virus (HIV)-associated dementia (HAD) is common among clade B HIV-infected individuals, but less common and less severe among…”
Get full text

The gp120 protein is a second determinant of decreased neurovirulence of Indian HIV-1C isolates compared to southern African HIV-1C isolates by Rao, Vasudev R, Neogi, Ujjwal, Eugenin, Eliseo, Prasad, Vinayaka R

“…Regional differences in neurovirulence have been documented among subtype/clade-C HIV-1 isolates in India and Southern Africa. We previously demonstrated that…”
Get full text

Role of macrophages in HIV pathogenesis and cure: NIH perspectives by Joseph, Jeymohan, Daley, William, Lawrence, Diane, Lorenzo, Eric, Perrin, Peter, Rao, Vasudev R., Tsai, Shang‐Yi, Varthakavi, Vasundhara

“…Macrophages play a significant role in HIV infection and contribute to pathogenesis of comorbidities as well as establishment of the viral reservoir in people…”
Get full text

Viral and cellular factors underlying neuropathogenesis in HIV associated neurocognitive disorders (HAND) by Rao, Vasudev R, Ruiz, Arthur P, Prasad, Vinayaka R

“…As the HIV-1 epidemic enters its fourth decade, HIV-1 associated neurological disorders (HAND) continue to be a major concern in the infected population,…”
Get full text

Biotypes of Central Nervous System Complications in People Living With Human Immunodeficiency Virus (HIV): National Institute of Mental Health Perspectives on Advancing the Future of HIV Healthcare by Rao, Vasudev R, Brouwers, Pim, Joseph, Jeymohan, Lawhorn, Collene, Scott Sheldon, Lori A J, Rausch, Dianne M

“…Abstract Despite effective suppressive antiretroviral therapy, central nervous system (CNS) complications related to human immunodeficiency virus (HIV) remain…”
Get full text

Global mental health and HIV care: gaps and research priorities by Senn, Theresa E, Greenwood, Gregory L, Rao, Vasudev R

“…Studies from the United States have shown that a combined approach integrating mental health treatment with HIV care interventions (e.g. Problem Solving…”
Get full text

Structural Determinants of Slippage-mediated Mutations by Human Immunodeficiency Virus Type 1 Reverse Transcriptase by Hamburgh, Monica E., Curr, Kenneth A., Monaghan, Melissa, Rao, Vasudev R., Tripathi, Snehlata, Preston, Bradley D., Sarafianos, Stefan, Arnold, Eddy, Darden, Thomas, Prasad, Vinayaka R.

“…Single-base deletions at nucleotide runs or -1 frameshifting by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) result from template…”
Get full text

An In Vitro Model of Blood-Brain Barrier for Studies on HIV Neuroinflammation and CNS Antibody Penetration by Lang, Yuekun, Mofed, Dina, Rao, Vasudev R, Welninski, Samantha J, Reyes, Anjelica F, Schneider, Jeffrey R, Prasad, Vinayaka R

“…The blood-brain barrier (BBB) is one of several barriers between the brain and the peripheral blood system to maintain homeostasis. Understanding the…”
Get more information

Evaluating the Role of Viral Proteins in HIV-Mediated Neurotoxicity Using Primary Human Neuronal Cultures by Rao, Vasudev R, Eugenin, Eliseo A, Prasad, Vinayaka R

“…Despite the inability of HIV-1 to infect neurons, over half of the HIV-1-infected population in the USA suffers from neurocognitive dysfunction. HIV-infected…”
Get more information

Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence by Rao, Vasudev R, Neogi, Ujjwal, Talboom, Joshua S, Padilla, Ligia, Rahman, Mustafizur, Fritz-French, Cari, Gonzalez-Ramirez, Sandra, Verma, Anjali, Wood, Charles, Ruprecht, Ruth M, Ranga, Udaykumar, Azim, Tasnim, Joska, John, Eugenin, Eliseo, Shet, Anita, Bimonte-Nelson, Heather, Tyor, William R, Prasad, Vinayaka R

“…HIV-1 Clade C (Subtype C; HIV-1C) is responsible for greater than 50% of infections worldwide. Unlike clade B HIV-1 (Subtype B; HIV-1B), which is known to…”
Get full text

Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure in Indian patients by Neogi, Ujjwal, Rao, Shwetha D, Bontell, Irene, Verheyen, Jens, Rao, Vasudev R, Gore, Sagar C, Soni, Neelesh, Shet, Anita, Schülter, Eugen, Ekstrand, Maria L, Wondwossen, Amogne, Kaiser, Rolf, Madhusudhan, Mallur S, Prasad, Vinayaka R, Sonnerborg, Anders

“…A novel tetra-peptide insertion was identified in Gag-p6 ALIX-binding region, which appeared in protease inhibitor failure Indian HIV-1C sequences (odds…”
Get full text

Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA by Joseph, Jeymohan, Cinque, Paola, Colosi, Deborah, Dravid, Ameet, Ene, Luminita, Fox, Howard, Gabuzda, Dana, Gisslen, Magnus, Beth Joseph, Sarah, Letendre, Scott, Mukerji, Shibani S., Nath, Avindra, Perez-Valero, Ignacio, Persaud, Deborah, Price, Richard W., Rao, Vasudev R., Sacktor, Ned, Swanstrom, Ronald, Winston, Alan, Wojna, Valerie, Wright, Edwina, Spudich, Serena

“…CSF HIV escape is a recently recognised phenomenon that suggests that despite suppressive treatment, HIV RNA may be detected in the CNS compartment in some…”
Get full text

Methods to study monocyte migration induced by HIV-infected cells by Rao, Vasudev R, Eugenin, Eliseo A, Berman, Joan W, Prasad, Vinayaka R

“…HIV-associated dementia (HAD) is a multi-factorial disease set in motion by the presence of HIV-infected cells in the brain. A characteristic feature of HAD is…”
Get more information

Novel tetra-peptide insertion in Gag-p6 ALIX-binding motif in HIV-1 subtype C associated with protease inhibitor failure by Neogi, Ujjwal, RAO, Shwetha D, BONTELL, Irene, VERHEYEN, Jens, RAO, Vasudev R, GORE, Sagar C, SONI, Neelesh, SHET, Anita, SCHÜLTER, Eugen, EKSTRAND, Maria L., WONDWOSSEN, Amogne, KAISER, Rolf, MADHUSUDHAN, Mallur S., PRASAD, Vinayaka R, SONNERBORG, Anders

“…A novel tetra-peptide insertion was identified in Gag-p6 ALIX-binding region which is appears in protease inhibitor (PI) failure Indian HIV-1C sequences (Odds…”
Get full text