Search Results - "Rao, Savita"

MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells by Dileepan, Mythili, Sarver, Anne E, Rao, Savita P, Panettieri, Jr, Reynold A, Subramanian, Subbaya, Kannan, Mathur S

“…Airway smooth muscle (ASM) cells play a critical role in the pathophysiology of asthma due to their hypercontractility and their ability to proliferate and…”
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Procedures to Evaluate Inflammatory and Pathological Changes During Allergic Airway Inflammation by Rao, Savita P, Rastle-Simpson, Stephanie, Dileepan, Mythili, Sriramarao, P

“…Cellular inflammation, with elevated levels of Th1/Th2 cytokines, airway mucus hypersecretion, and thickening of the airway smooth muscle, are characteristic…”
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FABP4 regulates eosinophil recruitment and activation in allergic airway inflammation by Ge, Xiao Na, Bastan, Idil, Dileepan, Mythili, Greenberg, Yana, Ha, Sung Gil, Steen, Kaylee A, Bernlohr, David A, Rao, Savita P, Sriramarao, P

“…Fatty acid binding protein 4 (FABP4), a member of a family of lipid-binding proteins, is known to play a role in inflammation by virtue of its ability to…”
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ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48 by Ha, Sung Gil, Ge, Xiao Na, Bahaie, Nooshin S., Kang, Bit Na, Rao, Amrita, Rao, Savita P., Sriramarao, P.

“…ORM (yeast)-like protein isoform 3 ( ORMDL3 ) has recently been identified as a candidate gene for susceptibility to asthma; however, the mechanisms by which…”
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Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1 by Ge, Xiao Na, Ha, Sung Gil, Greenberg, Yana G., Rao, Amrita, Bastan, Idil, Blidner, Ada G., Rao, Savita P., Rabinovich, Gabriel A., Sriramarao, P.

“…Galectin-1 (Gal-1), a glycan-binding protein with broad antiinflammatory activities, functions as a proresolving mediator in autoimmune and chronic…”
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Regulation of Eosinophil Recruitment and Allergic Airway Inflammation by Tropomyosin Receptor Kinase A by Dileepan, Mythili, Ge, Xiao Na, Bastan, Idil, Greenberg, Yana G, Liang, Yuying, Sriramarao, P, Rao, Savita P

“…Eosinophilia is a hallmark of allergic airway inflammation (AAI). Identifying key molecules and specific signaling pathways that regulate eosinophilic…”
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MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cells by Dileepan, Mythili, Jude, Joseph A, Rao, Savita P, Walseth, Timothy F, Panettieri, Reynold A, Subramanian, Subbaya, Kannan, Mathur S

“…The cell-surface protein CD38 mediates airway smooth muscle (ASM) contractility by generating cyclic ADP-ribose, a calcium-mobilizing molecule. In human ASM…”
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Regulation of serotonin-induced trafficking and migration of eosinophils by Kang, Bit Na, Ha, Sung Gil, Bahaie, Nooshin S, Hosseinkhani, M Reza, Ge, Xiao Na, Blumenthal, Malcolm N, Rao, Savita P, Sriramarao, P

“…Association of the neurotransmitter serotonin (5-HT) with the pathogenesis of allergic asthma is well recognized and its role as a chemoattractant for…”
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Inhibition of soluble epoxide hydrolase attenuates eosinophil recruitment and food allergen‐induced gastrointestinal inflammation by Bastan, Idil, Ge, Xiao Na, Dileepan, Mythili, Greenberg, Yana G., Guedes, Alonso G., Hwang, Sung Hee, Hammock, Bruce D., Washabau, Robert J., Rao, Savita P., Sriramarao, P.

“…Prevalence of food allergies in the United States is on the rise. Eosinophils are recruited to the intestinal mucosa in substantial numbers in food…”
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Effect Of Dual sEH/COX-2 Inhibition on Allergen-Induced Airway Inflammation by Dileepan, Mythili, Rastle-Simpson, Stephanie, Greenberg, Yana, Wijesinghe, Dayanjan S, Kumar, Naren Gajenthra, Yang, Jun, Hwang, Sung Hee, Hammock, Bruce D, Sriramarao, P, Rao, Savita P

“…Arachidonic acid metabolites resulting from the cyclooxygenase (COX), lipoxygenase, and cytochrome P450 oxidase enzymatic pathways play pro- and…”
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Allergen-induced airway remodeling is impaired in galectin-3-deficient mice by Ge, Xiao Na, Bahaie, Nooshin S, Kang, Bit Na, Hosseinkhani, M Reza, Ha, Sung Gil, Frenzel, Elizabeth M, Liu, Fu-Tong, Rao, Savita P, Sriramarao, P

“…The role played by the beta-galactoside-binding lectin galectin-3 (Gal-3) in airway remodeling, a characteristic feature of asthma that leads to airway…”
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Galectin-3 Functions as an Adhesion Molecule to Support Eosinophil Rolling and Adhesion under Conditions of Flow by Rao, Savita P, Wang, Zhuangzhi, Zuberi, Riaz I, Sikora, Lyudmila, Bahaie, Nooshin S, Zuraw, Bruce L, Liu, Fu-Tong, Sriramarao, P

“…Allergic inflammation involves the mobilization and trafficking of eosinophils to sites of inflammation. Galectin-3 (Gal-3) has been shown to play a critical…”
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Knob protein enhances epithelial barrier integrity and attenuates airway inflammation by Ha, Sung Gil, Dileepan, Mythili, Ge, Xiao Na, Kang, Bit Na, Greenberg, Yana G., Rao, Amrita, Muralidhar, Girija, Medina-Kauwe, Lali, Thompson, Michael A., Pabelick, Christina M., O'Grady, Scott M., Rao, Savita P., Sriramarao, P.

“…Altered epithelial physical and functional barrier properties along with TH1/TH2 immune dysregulation are features of allergic asthma. Regulation of junction…”
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Regulation of Eosinophil Recruitment and Activation by Galectins in Allergic Asthma by Rao, Savita P, Ge, Xiao Na, Sriramarao, P

“…Eosinophils are differentiated granulocytes that are recruited from the bone marrow to sites of inflammation the vascular system. Allergic asthma is…”
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Regulation of eosinophil recruitment and allergic airway inflammation by heparan sulfate proteoglycan (HSPG) modifying enzymes by Ge, Xiao Na, Bastan, Idil, Ha, Sung Gil, Greenberg, Yana G, Esko, Jeffrey D, Rao, Savita P, Sriramarao, P

“…HSPGs are glycoproteins containing covalently attached heparan sulfate (HS) chains which bind to growth factors, chemokines, etc., and regulate various aspects…”
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Assessment of eosinophils in gastrointestinal inflammatory disease of dogs by Bastan, Idil, Rendahl, Aaron K., Seelig, Davis, Day, Michael J., Hall, Edward J., Rao, Savita P., Washabau, Robert J., Sriramarao, P.

“…Background Accurate identification of eosinophils in the gastrointestinal (GI) tract of dogs with eosinophilic GI disease (EGID) by histological evaluation is…”
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Pulmonary delivery of ORMDL3 short hairpin RNA - a potential tool to regulate allergen-induced airway inflammation by Dileepan, Mythili, Ha, Sung Gil, Rastle-Simpson, Stephanie, Ge, Xiao Na, Greenberg, Yana G., Wijesinghe, Dayanjan S., Contaifer, Daniel, Rao, Savita P., Sriramarao, P.

“…Aim/Purpose: Exposure to various allergens has been shown to increase expression of ORMDL3 in the lung in models of allergic asthma. Studies using genetically…”
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Regulation of eosinophil trafficking by SWAP-70 and its role in allergic airway inflammation by Bahaie, Nooshin S, Hosseinkhani, M Reza, Ge, Xiao Na, Kang, Bit Na, Ha, Sung Gil, Blumenthal, Malcolm S, Jessberger, Rolf, Rao, Savita P, Sriramarao, P

“…Eosinophils are the predominant inflammatory cells recruited to allergic airways. In this article, we show that human and murine eosinophils express SWAP-70,…”
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Eosinophil-expressed galectin-3 regulates cell trafficking and migration by Ge, Xiao Na, Ha, Sung Gil, Liu, Fu-Tong, Rao, Savita P, Sriramarao, P

“…Galectin-3 (Gal-3), a β galactoside-binding lectin, is implicated in the pathogenesis of allergic airway inflammation and allergen-challenged mice deficient in…”
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Assessment of eosinophil peroxidase as a potential diagnostic and prognostic marker in dogs with inflammatory bowel disease by Bastan, Idil, Robinson, Nicholas A, Ge, Xiao Na, Rendahl, Aaron K, Rao, Savita P, Washabau, Robert J, Sriramarao, P

“…OBJECTIVE To evaluate a method for identifying intact and degranulated eosinophils in the small intestine of dogs with inflammatory bowel disease (IBD) by use…”
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