Search Results - "Rao, S. J. Aditya"

Evolutionary selectivity of amino acid is inspired from the enhanced structural stability and flexibility of the folded protein by Rao, S.J. Aditya, Shetty, Nandini P.

“…The present study attempts to decipher the site-specific amino acid alterations at certain positions experiencing preferential selectivity and their effect on…”
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Nrf2-regulated antioxidant response ameliorating ionizing radiation-induced damages explored through in vitro and molecular dynamics simulations by Selvan G, Tamizh, Ashok, Avinash Karkada, Rao S. J, Aditya, Gollapalli, Pavan, R, Vishakh, N, Suchetha Kumari, Chaudhury, Nabo K.

“…This study aims to investigate the mechanism of natural antioxidant ferulic acid (FA) in reducing oxidative stress followed by its inhibitory effect on the…”
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Receptor based virtual screening of potential novel inhibitors of tigar [TP53 (tumour protein 53)-induced glycolysis and apoptosis regulator by Poyya, Jagadeesha, Kumar, D. Jagadeesha, Nagendra, H.G., Dinesh, B., Aditya Rao, S.J., Joshi, Chandrashekhar G.

“…TP53 (tumor protein 53)-induced glycolysis and apoptosis regulator (TIGAR) belongs to the phosphatases family of proteins that modulates the level of reactive…”
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Multiple ligand simultaneous docking (MLSD): A novel approach to study the effect of inhibitors on substrate binding to PPO by Raghavendra, S., Aditya Rao, S.J., Kumar, Vadlapudi, Ramesh, C.K.

“…[Display omitted] •Concurrent interactions between the substrate and inhibitors with the enzyme polyphenol oxidase were studied.•Variation in binding dynamics…”
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Anti-listerial peptides from a marine Bacillus velezensis FTL7: production optimization, characterizations and molecular docking studies by Johny, Lidiya C., Kumar, B. S. Gnanesh, Rao, S. J. Aditya, Suresh, P. V.

“…Antimicrobial peptides (AMPs) with potent anti-listerial activity were characterized from a novel marine Bacillus velezensis FTL7. A Box-Behnken statistical…”
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Efficient L-Proline catalyzed synthesis of some new (4-substituted-phenyl)-1,5-dihydro-2H-pyrimido[4,5-d][1,3]thiazolo[3,2a]-pyrimidine-2,4(3H)-diones bearing thiazolopyrimidine derivatives and evaluation of their pharmacological activities by Sukanya, S.H., Venkatesh, Talavara, Aditya Rao, S.J., Joy, Muthipeedika Nibin

“…•Novel thaizole-pyrimidine derivatives were synthesised and spectroscopically characterised.•Cytotoxicity and anti-inflammatory activities were studied.•SAR…”
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Structure-based screening of natural product libraries in search of potential antiviral drug-leads as first-line treatment to COVID-19 infection by Rao, S.J. Aditya, Shetty, Nandini P.

“…The study focuses on identifying and screening natural products (NPs) based on their structural similarities with chemical drugs followed by their possible use…”
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Synthesis, Structure, and In Vitro Pharmacological Evaluation of some New Pyrimidine-2-Sulfonamide Derivatives and Their Molecular Docking Studies on Human Estrogen Receptor Alpha and CDK2/Cyclin Proteins by Jaber, Qassim A. H., Shentaif, Ahmed Hassen, Almajidi, Mohammed, Ahmad, Iqrar, Patel, Harun, Azad, Abul Kalam, Alnasser, Sulaiman Mohammed, Alatawi, Hanan Ali, Menaa, Farid, Alfaifi, Sulaiman Y.M., Rahman, Mohammed M., Ali, Meser M., Rao, S. J. Aditya

“…In this approach, novel pyrimidine-2-sulfonamide derivatives based on the 2 H -chromen-2-one moiety were synthesized and evaluated as anticancer and…”
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Facile CAN catalyzed one pot synthesis of novel indol-5,8-pyrimido[4,5-d]pyrimidine derivatives and their pharmacological study by Venkatesh, Talavara, Bodke, Yadav D, J, Aditya Rao S

“…In the present work a novel series of indol-5,8-pyrimido[4,5-d]pyrimidine derivatives (4a-l) have been synthesized by Biginelli reaction of…”
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Augmentation of pyrethrins content in callus of Chrysanthemum cinerariaefolium and establishing its insecticidal activity by molecular docking of NavMS Sodium Channel Pore receptor by Paramesha, M., Manivannan, S., Rao, S. J. Aditya, Srikanth, K. S., Neelwarne, Bhagyalakshmi, Shetty, Nandini P.

“…Pyrethrins are effective food-grade bio-pesticides obtained from the flowers of Chrysanthemum cinerariaefolium and this crop cannot be cultivated widely in…”
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Effect of dehydroabietylamine in angiogenesis and GSK3-β inhibition during wound healing activity in rats by Paramesha, Mahadevappa, Ramesh, Chapeyil Kumaran, Krishna, Venkatarangaiah, Kumar Swamy, H. Malleshappa, Aditya Rao, S. J., Hoskerri, Joy

“…The present research evaluates the wound healing capacity of dehydroabietylamine, a diterpenoid isolated from methanolic leaves extract of Carthamus tinctorius…”
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An efficient p‐TSA catalyzed synthesis of some new substituted‐(5‐hydroxy‐3‐phenylisoxazol‐4‐yl)‐1,3‐dimethyl‐1H‐chromeno[2,3‐d]pyrimidine‐2,4(3H,5H)‐dione/3,3‐dimethyl‐2H‐xanthen‐1(9H)‐one scaffolds and evaluation of their pharmacological and computational investigations by Sukanya, S H, Venkatesh, Talavara, Aditya Rao, S J, Pandith, Anup

“…•Novel substituted-(5-hydroxy-3-phenylisoxazol-4-yl)-1,3-dimethyl-1H-chromeno[2,3-d] pyrimidine-2,4(3H,5H)-dione/3,3-dimethyl-2H-xanthen-1(9H)-one derivatives…”
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Systems Pharmacology and Pharmacokinetics Strategy to Decode Bioactive Ingredients and Molecular Mechanisms from Zingiber officinale as Phyto-therapeutics against Neurological Diseases by Gollapalli, Pavan, Rao, Aditya S J, Manjunatha, Hanumanthappa, Selvan, Gnanasekaran Tamizh, Shetty, Praveenkumar, Kumari, Nalilu Suchetha

“…The bioactive constituents from Zingiber officinale (Z. officinale) have shown a positive effect on neurodegenerative diseases like Alzheimer's disease (AD),…”
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QUANTITATIVE ANALYSIS OF NATURAL ANTIOXIDANTS AND FREE RADICAL SCAVENGING ACTIVITIES OF CRUCIFERAE VEGETABLES by S, Jamuna K, K, Ramesh C, Sj, Aditya Rao, M, Paramesha, Mahmood, Riaz

“…Objective: The aim of this research program is to evaluate the antioxidant potentialities comprehensively utilizing commonly available cruciferous vegetables…”
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