Search Results - "Rao, Ravi D."
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Malignant melanoma in the 21st century, Part 1: Epidemiology, risk factors, screening, prevention, and diagnosis
Published in Mayo Clinic proceedings (01-03-2007)“…Malignant melanoma is an aggressive, therapy-resistant malignancy of melanocytes. The incidence of melanoma has been steadily increasing worldwide, resulting…”
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Malignant Melanoma in the 21st Century, Part 1: Epidemiology, Risk Factors, Screening, Prevention, and Diagnosis
Published in Mayo Clinic proceedings (2007)“…Malignant melanoma is an aggressive, therapy-resistant malignancy of melanocytes. The incidence of melanoma has been steadily increasing worldwide, resulting…”
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Malignant Melanoma in the 21st Century, Part 2: Staging, Prognosis, and Treatment
Published in Mayo Clinic proceedings (01-04-2007)“…Critical to the clinical management of a patient with malignant melanoma is an understanding of its natural history. As with most malignant disorders,…”
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The Paclitaxel acute pain syndrome: sensitization of nociceptors as the putative mechanism
Published in The cancer journal (Sudbury, Mass.) (01-11-2007)“…Paclitaxel therapy often result in a unique subacute pain syndrome, commonly termed "myalgia" or "arthralgia." The pathophysiology of this syndrome is unknown…”
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Current Strategies in Treatment of Oligodendroglioma: Evolution of Molecular Signatures of Response
Published in Journal of clinical oncology (10-03-2006)“…Oligodendroglioma frequently (> or = 70%) responds to radiation and chemotherapy, and is the first CNS neoplasm in which a genetic signature (1p and 19q…”
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Disruption of Parallel and Converging Signaling Pathways Contributes to the Synergistic Antitumor Effects of Simultaneous mTOR and EGFR Inhibition in GBM Cells
Published in Neoplasia (New York, N.Y.) (01-10-2005)“…Elevated epidermal growth factor receptor (EGFR) and mammalian target of rapamycin (mTOR) signaling are known to contribute to the malignant properties of…”
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Altered molecular pathways in gliomas: An overview of clinically relevant issues
Published in Seminars in oncology (01-10-2004)“…Primary central nervous system (CNS) tumors constitute a small fraction of the overall incidence of human cancer, but they represent a major source of…”
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Efficacy of gabapentin in the management of chemotherapy-induced peripheral neuropathy : A phase 3 randomized, double-blind, placebo-controlled, crossover trial (NOOC3)
Published in Cancer (01-11-2007)“…The antiepileptic agent, gabapentin, has been demonstrated to relieve symptoms of peripheral neuropathy due to various etiologies. On the basis of these data,…”
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Phase II Study of Everolimus in Metastatic Malignant Melanoma (NCCTG‐N0377, Alliance)
Published in The oncologist (Dayton, Ohio) (01-08-2018)“…Lessons Learned Everolimus does not have sufficient activity to justify its use as single agent in metastatic melanoma. Patients treated with 10 mg per day…”
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Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic
Published in Neuro-oncology (Charlottesville, Va.) (01-08-2009)“…The purpose of this study was to evaluate long-term survival in patients with nonpilocytic low-grade gliomas (LGGs). Records of 314 adult patients with…”
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Efficacy of Lamotrigine in the Management of Chemotherapy-induced Peripheral Neuropathy : A Phase 3 Randomized, Double-blind, Placebo-controlled Trial, N01C3
Published in Cancer (15-06-2008)“…Lamotrigine, an antiepileptic agent, has been reported as being effective in reducing symptoms of neuropathy associated with various etiologies. Based on such…”
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Combination of Temsirolimus (CCI-779) with Chemoradiation in Newly Diagnosed Glioblastoma Multiforme (GBM) (NCCTG trial N027D) Is Associated with Increased Infectious Risks
Published in Clinical cancer research (15-11-2010)“…The mammalian target of rapamycin (mTOR) functions within the phosphoinositide 3-kinase/Akt signaling pathway as a critical modulator of cell survival. The…”
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The continuing increase in the incidence of primary central nervous system non-Hodgkin lymphoma: A surveillance, epidemiology, and End Results analysis
Published in Cancer (01-10-2002)“…Primary central nervous system lymphoma (PCNSL) is an extranodal form of non-Hodgkin lymphoma arising in the craniospinal axis. The incidence of PCNSL appears…”
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Combination of paclitaxel and carboplatin as second‐line therapy for patients with metastatic melanoma
Published in Cancer (15-01-2006)“…BACKGROUND Patients with metastatic melanoma (MM) have very few therapy options. Based on reports of responses to paclitaxel and carboplatin (PC), 31 patients…”
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Intratracheal Melanoma Metastases
Published in The New England journal of medicine (28-09-2006)“…A 42-year-old woman with metastatic melanoma presented with a 1-month history of dyspnea and wheezing. The diagnosis of malignant melanoma had been made 6…”
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Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents
Published in Current cancer drug targets (01-12-2004)“…Highly specific signal transduction inhibitors are being developed as anti-cancer agents against an array of molecular targets, with the promise of increased…”
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Peptide vaccination of patients with metastatic melanoma: improved clinical outcome in patients demonstrating effective immunization
Published in American journal of clinical oncology (01-08-2006)“…Therapeutic peptide vaccines for melanoma continue to only demonstrate anecdotal success. We set out to evaluate the impact of low-dose GM-CSF emulsified in…”
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Melanoma-induced brain metastases
Published in Expert review of anticancer therapy (01-05-2008)“…Brain metastases are a common site of metastasis from malignant melanoma, and are associated with a poor prognosis. Diagnosis of brain metastasis may also have…”
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Chemotherapy-induced neuropathy
Published in Current oncology reports (01-07-2007)“…Peripheral neuropathy is a common dose-limiting toxicity of chemotherapy. Chemotherapy-induced peripheral neuropathy (CIPN) causes numerous debilitating…”
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Innovation in the management of brain metastases
Published in Oncology (Williston Park, N.Y.) (01-04-2007)“…Metastatic lesions to the brain occur commonly in oncology patients and portend a very poor outcome, as they often occur in the setting of progressive systemic…”
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