Search Results - "Rao, P. Sambasiva"

Human peripheral blood mononuclear cells exhibit heterogeneous CD52 expression levels and show differential sensitivity to alemtuzumab mediated cytolysis by Rao, Sambasiva P, Sancho, Jose, Campos-Rivera, Juanita, Boutin, Paula M, Severy, Peter B, Weeden, Timothy, Shankara, Srinivas, Roberts, Bruce L, Kaplan, Johanne M

“…Alemtuzumab is a monoclonal antibody that targets cell surface CD52 and is effective in depleting lymphocytes by cytolytic effects in vivo. Although the…”
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Animal immunization merges with innovative technologies: A new paradigm shift in antibody discovery by Prabakaran, Ponraj, Rao, Sambasiva P, Wendt, Maria

“…Animal-derived antibody sources, particularly, transgenic mice that are engineered with human immunoglobulin loci, along with advanced antibody generation…”
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Synthesis of novel 1,2,3-triazole/isoxazole functionalized 2H-Chromene derivatives and their cytotoxic activity by Ratnakar Reddy, K., Sambasiva Rao, P., Jitender Dev, G., Poornachandra, Y., Ganesh Kumar, C., Shanthan Rao, P., Narsaiah, B.

“…Novel 1,2,3-triazole 5a–q and isoxazole tagged 6a–i and 7a–g 2H-Chromene derivatives were prepared and screened for cytotoxic activity and promising compounds…”
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Synthesis of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives and their anticancer activity by Kurumurthy, C., Sambasiva Rao, P., Veera swamy, B., Santhosh kumar, G., Shanthan Rao, P., Narsaiah, B., Velatooru, L.R., Pamanji, R., Venkateswara Rao, J.

“…A series of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives 5 and 6 was prepared starting from 2,3-active functional pyridine 1 via cyclization,…”
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Large-scale antibody immune response mapping of splenic B cells and bone marrow plasma cells in a transgenic mouse model by Pan, Xiaoli, López Acevedo, Sheila N, Cuziol, Camille, De Tavernier, Evelyn, Fahad, Ahmed S, Longjam, Priyobarta S, Rao, Sambasiva P, Aguilera-Rodríguez, David, Rezé, Mathilde, Bricault, Christine A, Gutiérrez-González, Matías F, de Souza, Matheus Oliveira, DiNapoli, Joshua M, Vigne, Emmanuelle, Shahsavarian, Melody A, DeKosky, Brandon J

“…Molecular characterization of antibody immunity and human antibody discovery is mainly carried out using peripheral memory B cells, and occasionally…”
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Synthesis of novel 5-(3-alkylquinolin-2-yl)-3-aryl isoxazole derivatives and their cytotoxic activity by Sambasiva Rao, P, Kurumurthy, C, Veeraswamy, B, Poornachandra, Y, Ganesh Kumar, C, Narsaiah, B

“…The propargyl alcohol on reaction with aldoxime and NaOCl in DCM gave exclusively (3-arylisoxazol-5-yl) methanol 1. The compound 1 was oxidized to an aldehyde…”
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Diluted magnetic semiconductor properties in Zn1−xCuxO nanoparticles synthesized by sol gel route by Elilarassi, R., Sambasiva Rao, P., Chandrasekaran, G.

“…Nanoparticles of ZnO:Cu Diluted Magnetic Semiconductor (DMS) are prepared using sol gel method. The structural, optical and EPR properties of them are…”
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A platform-agnostic, function first-based antibody discovery strategy using plasmid-free mammalian expression of antibodies by Zhang, Ruijun, Prabakaran, Ponraj, Yu, Xiaocong, Mackness, Brian C, Boudanova, Ekaterina, Hopke, Joern, Sancho, Jose, Saleh, Jacqueline, Cho, HyunSuk, Zhang, Ningning, Simonds-Mannes, Helene, Stimple, Samuel D, Hoffmann, Dietmar, Park, Anna, Chowdhury, Partha S, Rao, Sambasiva P

“…Hybridoma technology has been valuable in the development of therapeutic antibodies. More recently, antigen-specific B-cell selection and display technologies…”
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Aberrant expression of functional BAFF-system receptors by malignant B-cell precursors impacts leukemia cell survival by Maia, Sara, Pelletier, Marc, Ding, Jixin, Hsu, Yen-Ming, Sallan, Stephen E, Rao, Sambasiva P, Nadler, Lee M, Cardoso, Angelo A

“…Despite exhibiting oncogenic events, patient's leukemia cells are responsive and dependent on signals from their malignant bone marrow (BM) microenvironment,…”
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Synthesis of novel 2-alkyl triazole-3-alkyl substituted quinoline derivatives and their cytotoxic activity by Sambasiva Rao, P., Kurumurthy, C., Veeraswamy, B., Santhosh Kumar, G., Shanthan Rao, P., Pamanji, R., Venkateswara Rao, J., Narsaiah, B.

“…Novel 2-alkyl triazole-3-alkyl substituted quinoline derivatives 5a–o were prepared in series of steps and screened for antimicrobial and cytotoxic activity…”
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Normal induction but attenuated progression of germinal center responses in BAFF and BAFF-R signaling-deficient mice by Rahman, Ziaur S M, Rao, Sambasiva P, Kalled, Susan L, Manser, Tim

“…The factors regulating germinal center (GC) B cell fate are poorly understood. Recent studies have defined a crucial role for the B cell-activating factor…”
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Synthesis of Novel Imidazo[1,2-a]pyrimidin-5(1H)-one Derivatives by Intramolecular Cycloisomerization of 2-Amino-3-alkynylpyrimidin-4(3H)-one in the Presence of Aqueous Base by Nagender, P, Reddy, G Malla, Rao, P Sambasiva, Kurumurthy, C, Rao, P Shanthan, Narsaiah, B

“…An efficient strategy has been developed for the synthesis of novel imidazo[1,2-a]pyrimidin-5(1H)-one derivatives 4 from 2-amino-3-alkynylpyrimidin-4(3H)-one 2…”
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Honing-in antigen-specific cells during antibody discovery: a user-friendly process to mine a deeper repertoire by Mahendra, Ankit, Haque, Aftabul, Prabakaran, Ponraj, Mackness, Brian C., Fuller, Thomas P., Liu, Xiaohua, Kathuria, Sagar V., Wang, Yui-Hsi, Amatya, Nilesh, Yu, Xiaocong, Hopke, Joern, Hoffmann, Dietmar, Bric-Furlong, Eva, Zhang, Ningning, Cho, Hyun-Suk, Zhang, Ruijun, Sancho, Jose, Saleh, Jacqueline, Rao, Sambasiva P., Wendt, Maria, Chowdhury, Partha S.

“…Immunization based antibody discovery is plagued by the paucity of antigen-specific B cells. Identifying these cells is akin to finding needle in a haystack…”
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Indium Triflate-promoted Synthesis of Novel 1,2,3-Triazole-, and Isoxazole-substituted Xanthene-1,8(2H)-dione Derivatives by Sambasiva Rao, P, Rathnakar Reddy, K, Nagender, P, Naresh Kumar, Royya, Shanthan Rao, Pamulaparthy, Narsaiah, Banda

“…An efficient synthetic protocol has been developed for the synthesis of the novel 1,2,3-triazole- and isoxazole-substituted xanthene-1,8(2H)-dione derivatives…”
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Efficient method for the synthesis of 1,2,3-triazole functionalized isoxazolidine derivatives by 1,3-dipolar cycloaddition of nitrones with terminal olefins by Sambasiva Rao, P., Ashalu, K. Chinna, Dev, G. Jitender, Ravi Kumar, N., Srinivas, P. V. S. S., Thomas, B. V., Narsaiah, B.

“…1-Phenyl-1,2,3-triazole-4-carbaldehyde 1 was treated with different N-alkyl hydroxylamine hydrochlorides 2 using NaHCO 3 to obtain 1,2,3-triazole substituted…”
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A Facile Approach for the Synthesis of Novel 1,2,4-Triazolo[4,3-a]Pyridine Derivatives in Single Step by Santhosh Kumar, G., Kurumurthy, C., Sambasiva Rao, P., Veeraswamy, B., Shanthan Rao, P., Narsaiah, B.

“…A series of novel substituted 4‐trifluoromethyl‐pyridin‐2‐yl hydrazide derivatives 5 and 7‐trifluoromethyl‐1,2,4‐triazolo[4,3‐a]pyridine derivatives 6 were…”
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Effect of Li2O content on physical and structural properties of vanadyl doped alkali zinc borate glasses by RAGHAVENDRA RAO, T, RAMA KRISHNA, Ch, UDAYACHANDRAN THAMPY, U. S, VENKATA REDDY, Ch, REDDY, Y. P, SAMBASIVA RAO, P, RAVIKUMAR, R. V. S. S. N

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Physical and spectral investigations of Mn²⁺ ions doped poly vinyl alcohol capped ZnSe nanoparticles by Muntaz Begum, Sk, Nirmala, G, Ravindranadh, K, Aswani, T, Rao, M.C, Sambasiva Rao, P, Ravikumar, R.V.S.S.N

“…Mn²⁺ doped ZnSe nanoparticles are prepared by using poly vinyl alcohol (PVA) as capping agent. Various physical parameters are calculated for the prepared…”
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Studies on Synthesis of Novel Pyrido[3,2-e]tetrazolo[1,5-c]pyrimidine Derivatives and Their Antimicrobial Activity by Veeraswamy, B., Santhosh Kumar, G., Sambasiva Rao, P., Kurumurthy, C., Narsaiah, B.

“…A series of novel pyrido[3,2‐e]tetrazolo[1,5‐c]pyrimidine derivative 4 were synthesized starting from 2‐amino‐4‐trifluoromethyl‐6‐phenyl nicotinonitrile 1 via…”
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Cutting Edge: Germinal Centers Formed in the Absence of B Cell-Activating Factor Belonging to the TNF Family Exhibit Impaired Maturation and Function by Vora, Kalpit A, Wang, Li Chun, Rao, Sambasiva P, Liu, Zhong-Ying, Majeau, Gerard R, Cutler, Anne H, Hochman, Paula S, Scott, Martin L, Kalled, Susan L

“…Germinal centers (GCs) form in B cell follicles and require specific signals for development and maintenance. B cell-activating factor belonging to the TNF…”
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