Search Results - "Rao, Lang"

Engineering Macrophages for Cancer Immunotherapy and Drug Delivery by Xia, Yuqiong, Rao, Lang, Yao, Huimin, Wang, Zhongliang, Ning, Pengbo, Chen, Xiaoyuan

“…Macrophages play an important role in cancer development and metastasis. Proinflammatory M1 macrophages can phagocytose tumor cells, while anti‐inflammatory M2…”
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Cell-Membrane-Mimicking Nanodecoys against Infectious Diseases by Rao, Lang, Tian, Rui, Chen, Xiaoyuan

“…Infectious diseases are a leading cause of mortality worldwide, with viruses and bacteria in particular having enormous impacts on global healthcare. One major…”
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Metal-free bioorthogonal click chemistry in cancer theranostics by Wu, Dan, Yang, Kuikun, Zhang, Zhankui, Feng, Yunxuan, Rao, Lang, Chen, Xiaoyuan, Yu, Guocan

“…Bioorthogonal chemistry is a powerful tool to site-specifically activate drugs in living systems. Bioorthogonal reactions between a pair of biologically…”
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Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy by Liang, Shuang, Yao, Jianjun, Liu, Dan, Rao, Lang, Chen, Xiaoyuan, Wang, Zhaohui

“…Immunotherapy has made remarkable strides in cancer therapy over the past decade. However, such emerging therapy still suffers from the low response rates and…”
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Supramolecular Polymerization‐Induced Nanoassemblies for Self‐Augmented Cascade Chemotherapy and Chemodynamic Therapy of Tumor by Yang, Kuikun, Yu, Guocan, Yang, Zhiqing, Yue, Ludan, Zhang, Xiangjun, Sun, Chen, Wei, Jianwen, Rao, Lang, Chen, Xiaoyuan, Wang, Ruibing

“…The clinical application of chemodynamic therapy is impeded by the insufficient intracellular H2O2 level in tumor tissues. Herein, we developed a…”
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Hybrid cellular membrane nanovesicles amplify macrophage immune responses against cancer recurrence and metastasis by Rao, Lang, Wu, Lei, Liu, Zhida, Tian, Rui, Yu, Guocan, Zhou, Zijian, Yang, Kuikun, Xiong, Hong-Gang, Zhang, Anli, Yu, Guang-Tao, Sun, Wenjing, Xu, Han, Guo, Jingya, Li, Andrew, Chen, Hongmin, Sun, Zhi-Jun, Fu, Yang-Xin, Chen, Xiaoyuan

“…Effectively activating macrophages against cancer is promising but challenging. In particular, cancer cells express CD47, a ‘don’t eat me’ signal that…”
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Zika virus infection induces host inflammatory responses by facilitating NLRP3 inflammasome assembly and interleukin-1β secretion by Wang, Wenbiao, Li, Geng, De Wu, Luo, Zhen, Pan, Pan, Tian, Mingfu, Wang, Yingchong, Xiao, Feng, Li, Aixin, Wu, Kailang, Liu, Xiaohong, Rao, Lang, Liu, Fang, Liu, Yingle, Wu, Jianguo

“…Zika virus (ZIKV) infection is a public health emergency and host innate immunity is essential for the control of virus infection. The NLRP3 inflammasome plays…”
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Extracellular vesicles: a rising star for therapeutics and drug delivery by Du, Shuang, Guan, Yucheng, Xie, Aihua, Yan, Zhao, Gao, Sijia, Li, Weirong, Rao, Lang, Chen, Xiaojia, Chen, Tongkai

“…Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the same nucleic acids, proteins, and lipids as their source cells…”
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Engineered Cellular Vesicles Displaying Glycosylated Nanobodies for Cancer Immunotherapy by Wu, Jicheng, Lu, Hailin, Xu, Ximing, Rao, Lang, Ge, Yun

“…Immune checkpoint blockade targeting the CD47/SIRPα axis represents an alluring avenue for cancer immunotherapy. However, the compromised efficacy and safety…”
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Decoy nanoparticles protect against COVID-19 by concurrently adsorbing viruses and inflammatory cytokines by Rao, Lang, Xia, Shuai, Xu, Wei, Tian, Rui, Yu, Guocan, Gu, Chenjian, Pan, Pan, Meng, Qian-Fang, Cai, Xia, Qu, Di, Lu, Lu, Xie, Youhua, Jiang, Shibo, Chen, Xiaoyuan

“…The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has highlighted the urgent need to rapidly develop therapeutic…”
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Activating Macrophage‐Mediated Cancer Immunotherapy by Genetically Edited Nanoparticles by Rao, Lang, Zhao, Shu‐Kun, Wen, Churan, Tian, Rui, Lin, Lisen, Cai, Bo, Sun, Yue, Kang, Fei, Yang, Zhen, He, Liangcan, Mu, Jing, Meng, Qian‐Fang, Yao, Guangyu, Xie, Ni, Chen, Xiaoyuan

“…Immunomodulation of macrophages against cancer has emerged as an encouraging therapeutic strategy. However, there exist two major challenges in effectively…”
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Intelligent Scheduling Methodology for UAV Swarm Remote Sensing in Distributed Photovoltaic Array Maintenance by An, Qing, Hu, Qiqi, Tang, Ruoli, Rao, Lang

“…In recent years, the unmanned aerial vehicle (UAV) remote sensing technology has been widely used in the planning, design and maintenance of urban distributed…”
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Engineered Cell Membrane‐Derived Nanoparticles in Immune Modulation by Yang, Yixiao, Wang, Kai, Pan, Yuanwei, Rao, Lang, Luo, Gaoxing

“…Immune modulation is one of the most effective approaches in the therapy of complex diseases, including public health emergency. However, most immune…”
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Macrophages in immunoregulation and therapeutics by Chen, Shanze, Saeed, Abdullah F.U.H., Liu, Quan, Jiang, Qiong, Xu, Haizhao, Xiao, Gary Guishan, Rao, Lang, Duo, Yanhong

“…Macrophages exist in various tissues, several body cavities, and around mucosal surfaces and are a vital part of the innate immune system for host defense…”
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Vesicular Antibodies: Shedding Light on Antibody Therapeutics with Cell Membrane Nanotechnology by Zhao, Chenchen, Pan, Yuanwei, Yu, Guocan, Zhao, Xing‐Zhong, Chen, Xiaoyuan, Rao, Lang

“…The high stability of antibodies and their ability to precisely bind to antigens and endogenous immune receptors, as well as their susceptibility to protein…”
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Genetically Programmable Fusion Cellular Vesicles for Cancer Immunotherapy by Meng, Qian‐Fang, Zhao, Yuyue, Dong, Chunbo, Liu, Lujie, Pan, Yuanwei, Lai, Jialin, Liu, Zhida, Yu, Guang‐Tao, Chen, Xiaoyuan, Rao, Lang

“…Herein, we report that genetically programmable fusion cellular vesicles (Fus‐CVs) displaying high‐affinity SIRPα variants and PD‐1 can activate potent…”
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Cancer Cell Membrane‐Coated Nanoparticles for Personalized Therapy in Patient‐Derived Xenograft Models by Rao, Lang, Yu, Guang‐Tao, Meng, Qian‐Fang, Bu, Lin‐Lin, Tian, Rui, Lin, Li‐Sen, Deng, Hongzhang, Yang, Weijing, Zan, Minghui, Ding, Jianxun, Li, Andrew, Xiao, Haihua, Sun, Zhi‐Jun, Liu, Wei, Chen, Xiaoyuan

“…Cell membrane coating nanotechnology, which endows nanoparticles with unique properties, displays excellent translational potential in cancer diagnosis and…”
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Platelet–Leukocyte Hybrid Membrane‐Coated Immunomagnetic Beads for Highly Efficient and Highly Specific Isolation of Circulating Tumor Cells by Rao, Lang, Meng, Qian‐Fang, Huang, Qinqin, Wang, Zixiang, Yu, Guang‐Tao, Li, Andrew, Ma, Weijie, Zhang, Nangang, Guo, Shi‐Shang, Zhao, Xing‐Zhong, Liu, Kan, Yuan, Yufeng, Liu, Wei

“…Biomimetic cell‐membrane‐camouflaged nanoparticles with desirable features have been widely used for various biomedical applications. However, the current…”
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Tumor Microenvironment‐Responsive Nanoparticles Amplifying STING Signaling Pathway for Cancer Immunotherapy by Liu, Dan, Liang, Shuang, Ma, Kongshuo, Meng, Qian‐Fang, Li, Xingang, Wei, Jian, Zhou, Mengli, Yun, Kaiqing, Pan, Yuanwei, Rao, Lang, Chen, Xiaoyuan, Wang, Zhaohui

“…Insufficient activation of the stimulator of interferon genes (STING) signaling pathway and profoundly immunosuppressive microenvironment largely limits the…”
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Neutrophil Membrane‐Camouflaged Polyprodrug Nanomedicine for Inflammation Suppression in Ischemic Stroke Therapy by Zhao, Ya, Li, Qian, Niu, Jingyan, Guo, Erliang, Zhao, Chenchen, Zhang, Jian, Liu, Xue, Wang, Lihua, Rao, Lang, Chen, Xiaoyuan, Yang, Kuikun

“…Neuroinflammation has emerged as a major concern in ischemic stroke therapy because it exacebates neurological dysfunction and suppresses neurological recovery…”
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