Search Results - "Rao, Han Zhi"

Hematopoietic cell-mediated dissemination of murine cytomegalovirus is regulated by NK cells and immune evasion by Zhang, Shunchuan, Springer, Lauren E, Rao, Han-Zhi, Espinosa Trethewy, Renee G, Bishop, Lindsey M, Hancock, Meaghan H, Grey, Finn, Snyder, Christopher M

“…Cytomegalovirus (CMV) causes clinically important diseases in immune compromised and immune immature individuals. Based largely on work in the mouse model of…”
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Long-term Improvements in Lifespan and Pathology in CNS and PNS After BMT Plus One Intravenous Injection of AAVrh10-GALC in Twitcher Mice by Rafi, Mohammad A, Rao, Han Zhi, Luzi, Paola, Wenger, David A

“…Krabbe disease is an autosomal recessive disorder resulting from defects in the lysosomal enzyme galactocerebrosidase (GALC). GALC deficiency leads to severe…”
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Sixteen novel mutations in the arylsulfatase A gene causing metachromatic leukodystrophy by Luzi, Paola, Rafi, Mohammad A., Rao, Han Zhi, Wenger, David A.

“…Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder caused mainly by mutations in the arylsulfatase A (ARSA) gene. In this manuscript we report…”
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Generation of transgenic mice expressing insulin-like growth factor-1 under the control of the myelin basic protein promoter: increased myelination and potential for studies on the effects of increased IGF-1 on experimentally and genetically induced demyelination by Luzi, Paola, Zaka, Mariam, Rao, Han Zhi, Curtis, Mark, Rafi, Mohammad A, Wenger, David A

“…In order to investigate a role for insulin-like growth factor-1 (IGF-1) in ameliorating the effects of demyelinating events and potentiating remyelination, we…”
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AAV-Mediated expression of galactocerebrosidase in brain results in attenuated symptoms and extended life span in murine models of globoid cell leukodystrophy by Rafi, Mohammad A., Zhi Rao, Han, Passini, Marco A., Curtis, Mark, Vanier, Marie T., Zaka, Mariam, Luzi, Paola, Wolfe, John H., Wenger, David A.

“…Globoid cell leukodystrophy (GLD) or Krabbe disease is a neurodegenerative disorder caused by a deficiency of galactocerebrosidase (GALC) activity. GALC is…”
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Biochemical and pathological evaluation of long-lived mice with globoid cell leukodystrophy after bone marrow transplantation by Luzi, Paola, Rafi, Mohammad A., Zaka, Mariam, Rao, Han Zhi, Curtis, Mark, Vanier, Marie T., Wenger, David A.

“…Globoid cell leukodystrophy (GLD) is a disorder of the central and peripheral nervous systems caused by the deficiency of the lysosomal enzyme…”
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Extended Normal Life After AAVrh10-mediated Gene Therapy in the Mouse Model of Krabbe Disease by Rafi, Mohammad A, Rao, Han Zhi, Luzi, Paola, Curtis, Mark T, Wenger, David A

“…Globoid cell leukodystrophy (GLD) or Krabbe disease is a neurodegenerative disorder caused by the deficiency of the lysosomal enzyme galactocerebrosidase…”
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Intravenous injection of AAVrh10-GALC after the neonatal period in twitcher mice results in significant expression in the central and peripheral nervous systems and improvement of clinical features by Rafi, Mohammad A., Rao, Han Zhi, Luzi, Paola, Luddi, Alice, Curtis, Mark T., Wenger, David A.

“…Globoid cell leukodystrophy (GLD) or Krabbe disease is an autosomal recessive disorder resulting from the defective lysosomal enzyme galactocerebrosidase…”
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Use of AAVrh10-GALC to Treat the Twitcher Mouse Model of Krabbe Disease by Wenger, David, Rafi, Mohammad, Luzi, Paola, Rao, Han Zhi

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Insulin-like growth factor-1 provides protection against psychosine-induced apoptosis in cultured mouse oligodendrocyte progenitor cells using primarily the PI3K/Akt pathway by Zaka, Mariam, Rafi, Mohammad A., Rao, Han Zhi, Luzi, Paola, Wenger, David A.

“…Psychosine (galactosylsphingosine) is a toxic metabolite that accumulates in globoid cell leukodystrophy (GLD) due to the deficiency of galactocerebrosidase…”
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212. Delivery of Galactocerebrosidase Activity to the Peripheral Nervous System of Mice with Globoid Cell Leukodystrophy (Krabbe Disease) by Intramuscular Injection by Rafi, Mohammad A., Zhi Rao, Han, Luzi, Paola, Curtis, Mark T., Wenger, David A.

“…Globoid cell leukodystrophy (GLD) or Krabbe disease is a neurodegenerative disorder that affects both the central and peripheral nervous system (CNS and PNS)…”
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Disease-causing mutations in cis with the common arylsulfatase A pseudodeficiency allele compound the difficulties in accurately identifying patients and carriers of metachromatic leukodystrophy by Rafi, Mohammad A, Coppola, Stephanie, Liu, Shu Ling, Rao, Han Zhi, Wenger, David A

“…Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder most often caused by mutations in the sulfatide sulfatase or arylsulfatase A (ASA) gene…”
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