Search Results - "Rao, Desirazu N"

Promiscuous DNA cleavage by HpyAII endonuclease is modulated by the HNH catalytic residues by Kumar, Sumith, Bangru, Sushant, Kumar, Ritesh, Rao, Desirazu N

“…Helicobacter pylori is a carcinogenic bacterium that is responsible for 5.5% of all human gastric cancers. H. pylori codes for an unusually large number of…”
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Mechanism of formation of a toroid around DNA by the mismatch sensor protein by Nirwal, Shivlee, Kulkarni, Dhananjaya S, Sharma, Amit, Rao, Desirazu N, Nair, Deepak T

“…Abstract The DNA mismatch repair (MMR) pathway removes errors that appear during genome replication. MutS is the primary mismatch sensor and forms an…”
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Identification of the periplasmic DNA receptor for natural transformation of Helicobacter pylori by Damke, Prashant P., Di Guilmi, Anne Marie, Varela, Paloma Fernández, Velours, Christophe, Marsin, Stéphanie, Veaute, Xavier, Machouri, Mérick, Gunjal, Gaurav V., Rao, Desirazu N., Charbonnier, Jean-Baptiste, Radicella, J. Pablo

“…Horizontal gene transfer through natural transformation is a major driver of antibiotic resistance spreading in many pathogenic bacterial species. In the case…”
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The C-terminal domain is sufficient for endonuclease activity of Neisseria gonorrhoeae MutL by Duppatla, Viswanadham, Bodda, Chiranjeevi, Urbanke, Claus, Friedhoff, Peter, Rao, Desirazu N

“…The mutL gene of Neisseria gonorrhoeae has been cloned and the gene product purified. We have found that the homodimeric N. gonorrhoeae MutL (NgoL) protein…”
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Comparative transcriptomics of H. pylori strains AM5, SS1 and their hpyAVIBM deletion mutants: possible roles of cytosine methylation by Kumar, Ritesh, Mukhopadhyay, Asish K, Ghosh, Prachetash, Rao, Desirazu N

“…Helicobacter pylori is an important human pathogen and one of the most successful chronic colonizers of the human body. H. pylori uses diverse mechanisms to…”
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Correction to: Mutations in the nucleotide binding and hydrolysis domains of helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function by Damke, Prashant P, Dhanaraju, Rajkumar, Marsin, Stéphanie, Radicella, J Pablo, Rao, Desirazu N

“…Following publication of the original article [1], the authors notified us of an error in the presentation of Fig. 6G…”
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Structure, function and mechanism of exocyclic DNA methyltransferases by Bheemanaik, Shivakumara, Reddy, Yeturu V R, Rao, Desirazu N

“…DNA MTases (methyltransferases) catalyse the transfer of methyl groups to DNA from AdoMet (S-adenosyl-L-methionine) producing AdoHcy…”
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Functional analysis of an acid adaptive DNA adenine methyltransferase from Helicobacter pylori 26695 by Banerjee, Arun, Rao, Desirazu N

“…HP0593 DNA-(N(6)-adenine)-methyltransferase (HP0593 MTase) is a member of a Type III restriction-modification system in Helicobacter pylori strain 26695…”
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Role(s) of Acetylation in human pathogen Helicobacter pylori by Rao, Desirazu N.

“…Helicobacter pyloris (H.pylori) a Gram‐negative bacterium whose infection of the human stomach triggers a chronic gastritis that can evolve into a series of…”
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Role of DNA methyltransferases in epigenetic regulation in bacteria by Kumar, Ritesh, Rao, Desirazu N

“…In prokaryotes, alteration in gene expression was observed with the modification of DNA, especially DNA methylation. Such changes are inherited from generation…”
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Distinct properties of hexameric but functionally conserved Mycobacterium tuberculosis transcription-repair coupling factor by Prabha, Swayam, Rao, Desirazu N, Nagaraja, Valakunja

“…Transcription coupled nucleotide excision repair (TC-NER) is involved in correcting UV-induced damage and other road-blocks encountered in the transcribed…”
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Fast-scan atomic force microscopy reveals that the type III restriction enzyme EcoP15I is capable of DNA translocation and looping by Crampton, Neal, Yokokawa, Masatoshi, Dryden, David T.F, Edwardson, J. Michael, Rao, Desirazu N, Takeyasu, Kunio, Yoshimura, Shige H, Henderson, Robert M

“…Many DNA-modifying enzymes act in a manner that requires communication between two noncontiguous DNA sites. These sites can be brought into contact either by a…”
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Insights into the Functional Roles of N-Terminal and C-Terminal Domains of Helicobacter pylori DprA by Dwivedi, Gajendradhar R, Srikanth, Kolluru D, Anand, Praveen, Naikoo, Javed, Srilatha, N S, Rao, Desirazu N

“…DNA processing protein A (DprA) plays a crucial role in the process of natural transformation. This is accomplished through binding and subsequent protection…”
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Structural similarities between SAM and ATP recognition motifs and detection of ATP binding in a SAM binding DNA methyltransferase by Sankar, Santhosh, Preeti, Preeti, Ravikumar, Kavya, Kumar, Amrendra, Prasad, Yedu, Pal, Sukriti, Rao, Desirazu N, Savithri, Handanahal S, Chandra, Nagasuma

“…S-adenosylmethionine (SAM) is a ubiquitous co-factor that serves as a donor for methylation reactions and additionally serves as a donor of other functional…”
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The nuclease activities of both the Smr domain and an additional LDLK motif are required for an efficient anti‐recombination function of Helicobacter pylori MutS2 by Damke, Prashant P., Dhanaraju, Rajkumar, Marsin, Stéphanie, Radicella, Juan Pablo, Rao, Desirazu N.

“…Summary Helicobacter pylori, a human pathogen, is a naturally and constitutively competent bacteria, displaying a high rate of intergenomic recombination…”
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The C-terminal domain of the MutL homolog from Neisseria gonorrhoeae forms an inverted homodimer by Namadurai, Sivakumar, Jain, Deepti, Kulkarni, Dhananjay S, Tabib, Chaitanya R, Friedhoff, Peter, Rao, Desirazu N, Nair, Deepak T

“…The mismatch repair (MMR) pathway serves to maintain the integrity of the genome by removing mispaired bases from the newly synthesized strand. In E. coli,…”
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A nucleotide insertion between two adjacent methyltransferases in Helicobacter pylori results in a bifunctional DNA methyltransferase by Kumar, Ritesh, Rao, Desirazu N

“…Helicobacter pylori has a dynamic R-M (restriction-modification) system. It is capable of acquiring new R-M systems from the environment in the form of DNA…”
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Mutations in the nucleotide binding and hydrolysis domains of Helicobacter pylori MutS2 lead to altered biochemical activities and inactivation of its in vivo function by Damke, Prashant P, Dhanaraju, Rajkumar, Marsin, Stéphanie, Radicella, J Pablo, Rao, Desirazu N

“…Helicobacter pylori MutS2 (HpMutS2), an inhibitor of recombination during transformation is a non-specific nuclease with two catalytic sites, both of which are…”
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Type III restriction-modification enzymes: a historical perspective by Rao, Desirazu N, Dryden, David T F, Bheemanaik, Shivakumara

“…Restriction endonucleases interact with DNA at specific sites leading to cleavage of DNA. Bacterial DNA is protected from restriction endonuclease cleavage by…”
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Characterization of an N⁶ adenine methyltransferase from Helicobacter pylori strain 26695 which methylates adjacent adenines on the same strand by Kumar, Ritesh, Mukhopadhyay, Asish K, Rao, Desirazu N

“…Genomic sequences of Helicobacter pylori strains 26695, J99, HPAGI and G27 have revealed an abundance of restriction and modification genes. hp0050, which…”
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