Search Results - "Ranzau, Brodie L."

Expanded palette of RNA base editors for comprehensive RBP-RNA interactome studies by Medina-Munoz, Hugo C., Kofman, Eric, Jagannatha, Pratibha, Boyle, Evan A., Yu, Tao, Jones, Krysten L., Mueller, Jasmine R., Lykins, Grace D., Doudna, Andrew T., Park, Samuel S., Blue, Steven M., Ranzau, Brodie L., Kohli, Rahul M., Komor, Alexis C., Yeo, Gene W.

“…RNA binding proteins (RBPs) are key regulators of RNA processing and cellular function. Technologies to discover RNA targets of RBPs such as TRIBE (targets of…”
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Development of multiplexed orthogonal base editor (MOBE) systems by Cowan, Quinn T, Gu, Sifeng, Gu, Wanjun, Ranzau, Brodie L, Simonson, Tatum S, Komor, Alexis C

“…Base editors (BEs) enable efficient, programmable installation of point mutations while avoiding the use of double-strand breaks. Simultaneous application of…”
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Genome, Epigenome, and Transcriptome Editing via Chemical Modification of Nucleobases in Living Cells by Ranzau, Brodie L, Komor, Alexis C

“…Base editors are tools that chemically modify the nucleobases of DNA and RNA in a programmable manner, allowing for genome, epigenome, and transcriptome…”
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The Wild‐Type tRNA Adenosine Deaminase Enzyme TadA Is Capable of Sequence‐Specific DNA Base Editing by Ranzau, Brodie L., Rallapalli, Kartik L., Evanoff, Mallory, Paesani, Francesco, Komor, Alexis C.

“…Base editors are genome editing tools that enable site‐specific base conversions through the chemical modification of nucleobases in DNA. Adenine base editors…”
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Front Cover: The Wild‐Type tRNA Adenosine Deaminase Enzyme TadA Is Capable of Sequence‐Specific DNA Base Editing (ChemBioChem 16/2023) by Ranzau, Brodie L., Rallapalli, Kartik L., Evanoff, Mallory, Paesani, Francesco, Komor, Alexis C.

“…The directed evolution of the adenosine deaminase enzyme TadA from an RNA‐editing enzyme to an efficient DNA‐editing enzyme was crucial for the development of…”
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Curing "GFP-itis" in Bacteria with Base Editors: Development of a Genome Editing Science Program Implemented with High School Biology Students by Vasquez, Carlos A, Evanoff, Mallory, Ranzau, Brodie L, Gu, Sifeng, Deters, Emma, Komor, Alexis C

“…The flexibility and precision of CRISPR-Cas9 and related technologies have made these genome editing tools increasingly popular in agriculture, medicine, and…”
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Combined Theoretical, Bioinformatic, and Biochemical Analyses of RNA Editing by Adenine Base Editors by Rallapalli, Kartik L, Ranzau, Brodie L, Ganapathy, Kaushik R, Paesani, Francesco, Komor, Alexis C

“…Adenine base editors (ABEs) have been subjected to multiple rounds of mutagenesis with the goal of optimizing their function as efficient and precise genome…”
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Studying the Sequence Recognition Properties of Base Editing Enzymes by Ranzau, Brodie L

“…Base editors are tools that chemically modify the nucleobases of DNA and RNA in a programmable manner, allowing for genome, epigenome, and transcriptome…”
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Evidence of a Perilipin‐5 Splice Variant by Ranzau, Brodie L., DuBreuil, Daniel M, Hubbell, Theresa, Tansey, John T

“…Abstract only The large diversity of proteins found within animals are made possible through alternative splicing of mRNA. This has been shown to occur within…”
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