Search Results - "Ranucci, Colette S."
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Control of hepatocyte function on collagen foams: sizing matrix pores toward selective induction of 2-D and 3-D cellular morphogenesis
Published in Biomaterials (01-04-2000)“…While microporous biopolymer matrices are being widely tested as cell culture substrates in hepatic tissue engineering, the microstructural basis for their…”
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2
Mechanochemical manipulation of hepatocyte aggregation can selectively induce or repress liver-specific function
Published in Biotechnology and bioengineering (20-08-2000)“…Controlled activation of hepatocyte aggregation is critical to three‐dimensional (3D) multicellular morphogenesis during native regeneration of liver as well…”
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Development, clinical evaluation, and post-licensure impact of RotaTeq, a pentavalent rotavirus vaccine
Published in Annals of the New York Academy of Sciences (01-03-2011)“…Rotavirus gastroenteritis (RVGE) is the leading cause of severe diarrhea in children worldwide. This paper provides an overview of the development, clinical…”
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4
Monoclonal Antibody Process Development Using Medium Concentrates
Published in Biotechnology progress (01-01-1994)“…A fed‐batch process using concentrated medium was evaluated for its ability to improve cell culture longevity and final monoclonal antibody (MAb) titers for…”
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5
Tissue assembly guided via substrate biophysics: applications to hepatocellular engineering
Published in Advances in biochemical engineering, biotechnology (2006)“…The biophysical nature of the cellular microenvironment, in combination with its biochemical properties, can critically modulate the outcome of…”
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6
Fluid mechanics, cell distribution, and environment in CellCube bioreactors
Published in Biotechnology progress (2003)“…Cultivation of MRC-5 cells and attenuated hepatitis A virus (HAV) for the production of VAQTA, an inactivated HAV vaccine (1), is performed in the CellCube…”
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7
Polymer substrate topography actively regulates the multicellular organization and liver-specific functions of cultured hepatocytes
Published in Tissue engineering (01-10-1999)“…This study examines the role of topography of porous synthetic polymer substrates in regulating the tissue-specific morphogenesis of cultured hepatocytes…”
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8
Development, clinical evaluation, and postalicensure impact of RotaTeq, a pentavalent rotavirus vaccine
Published in Annals of the New York Academy of Sciences (01-03-2011)“…Rotavirus gastroenteritis (RVGE) is the leading cause of severe diarrhea in children worldwide. This paper provides an overview of the development, clinical…”
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Journal Article -
9
Substrate microtopography can enhance cell adhesive and migratory responsiveness to matrix ligand density
Published in Journal of biomedical materials research (01-02-2001)“…The regulation of cell motility by ligand density on substrates with variable microtopography is not well understood. In this report, we studied the adhesion…”
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10
Fluid Mechanics, Cell Distribution, and Environment in Cell Cube Bioreactors
Published in Biotechnology progress (2003)“…Cultivation of MRC‐5 cells and attenuated hepatitis A virus (HAV) for the production of VAQTA, an inactivated HAV vaccine ( 1), is performed in the Cell Cube…”
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Journal Article