Search Results - "Ranson, Janice M."

Mediterranean diet adherence is associated with lower dementia risk, independent of genetic predisposition: findings from the UK Biobank prospective cohort study by Shannon, Oliver M, Ranson, Janice M, Gregory, Sarah, Macpherson, Helen, Milte, Catherine, Lentjes, Marleen, Mulligan, Angela, McEvoy, Claire, Griffiths, Alex, Matu, Jamie, Hill, Tom R, Adamson, Ashley, Siervo, Mario, Minihane, Anne Marie, Muniz-Tererra, Graciela, Ritchie, Craig, Mathers, John C, Llewellyn, David J, Stevenson, Emma

“…The identification of effective dementia prevention strategies is a major public health priority, due to the enormous and growing societal cost of this…”
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Interaction between genetic predisposition, smoking, and dementia risk: a population-based cohort study by Zhang, Na, Ranson, Janice M., Zheng, Zhi-Jie, Hannon, Eilis, Zhou, Zhenwei, Kong, Xuejun, Llewellyn, David J., King, Daniel A., Huang, Jie

“…We evaluated whether the association between cigarette smoking and dementia risk is modified by genetic predisposition including apolipoprotein E (APOE)…”
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Harnessing transcriptomic signals for amyotrophic lateral sclerosis to identify novel drugs and enhance risk prediction by Pain, Oliver, Jones, Ashley, Al Khleifat, Ahmad, Agarwal, Devika, Hramyka, Dzmitry, Karoui, Hajer, Kubica, Jędrzej, Llewellyn, David J., Ranson, Janice M., Yao, Zhi, Iacoangeli, Alfredo, Al-Chalabi, Ammar

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. This study integrates common genetic association results from the latest ALS…”
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Harnessing the potential of machine learning and artificial intelligence for dementia research by Ranson, Janice M., Bucholc, Magda, Lyall, Donald, Newby, Danielle, Winchester, Laura, Oxtoby, Neil P., Veldsman, Michele, Rittman, Timothy, Marzi, Sarah, Skene, Nathan, Al Khleifat, Ahmad, Foote, Isabelle F., Orgeta, Vasiliki, Kormilitzin, Andrey, Lourida, Ilianna, Llewellyn, David J.

“…Progress in dementia research has been limited, with substantial gaps in our knowledge of targets for prevention, mechanisms for disease progression, and…”
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Frailty, lifestyle, genetics and dementia risk by Ward, David D, Ranson, Janice M, Wallace, Lindsay M K, Llewellyn, David J, Rockwood, Kenneth

“…ObjectiveTo optimise dementia prevention strategies, we must understand the complex relationships between lifestyle behaviours, frailty and genetics.MethodsWe…”
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Performance of Machine Learning Algorithms for Predicting Progression to Dementia in Memory Clinic Patients by James, Charlotte, Ranson, Janice M, Everson, Richard, Llewellyn, David J

“…Machine learning algorithms could be used as the basis for clinical decision-making aids to enhance clinical practice. To assess the ability of machine…”
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Socioeconomic Deprivation, Genetic Risk, and Incident Dementia by Klee, Matthias, Leist, Anja K., Veldsman, Michele, Ranson, Janice M., Llewellyn, David J.

“…Socioeconomic factors and genetic predisposition are established risk factors for dementia. It remains unclear whether associations of socioeconomic…”
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Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia by Winchester, Laura M., Harshfield, Eric L., Shi, Liu, Badhwar, AmanPreet, Khleifat, Ahmad Al, Clarke, Natasha, Dehsarvi, Amir, Lengyel, Imre, Lourida, Ilianna, Madan, Christopher R., Marzi, Sarah J., Proitsi, Petroula, Rajkumar, Anto P., Rittman, Timothy, Silajdžić, Edina, Tamburin, Stefano, Ranson, Janice M., Llewellyn, David J.

“…With the increase in large multimodal cohorts and high‐throughput technologies, the potential for discovering novel biomarkers is no longer limited by data set…”
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Artificial intelligence for dementia research methods optimization by Bucholc, Magda, James, Charlotte, Khleifat, Ahmad Al, Badhwar, AmanPreet, Clarke, Natasha, Dehsarvi, Amir, Madan, Christopher R., Marzi, Sarah J., Shand, Cameron, Schilder, Brian M., Tamburin, Stefano, Tantiangco, Hanz M., Lourida, Ilianna, Llewellyn, David J., Ranson, Janice M.

“…Artificial intelligence (AI) and machine learning (ML) approaches are increasingly being used in dementia research. However, several methodological challenges…”
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PAGEANT: personal access to genome and analysis of natural traits by Huang, Jie, Liang, Zhi-Sheng, Pallotti, Stefano, Ranson, Janice M, Llewellyn, David J, Zheng, Zhi-Jie, King, Daniel A, Zhou, Qiang, Zheng, Houfeng, Napolioni, Valerio

“…Abstract GWASs have identified numerous genetic variants associated with a wide variety of diseases, yet despite the wide availability of genetic testing the…”
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Artificial intelligence for dementia drug discovery and trials optimization by Doherty, Thomas, Yao, Zhi, Khleifat, Ahmad A.l., Tantiangco, Hanz, Tamburin, Stefano, Albertyn, Chris, Thakur, Lokendra, Llewellyn, David J., Oxtoby, Neil P., Lourida, Ilianna, Ranson, Janice M., Duce, James A.

“…Drug discovery and clinical trial design for dementia have historically been challenging. In part these challenges have arisen from patient heterogeneity,…”
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Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review by Borchert, Robin J., Azevedo, Tiago, Badhwar, AmanPreet, Bernal, Jose, Betts, Matthew, Bruffaerts, Rose, Burkhart, Michael C., Dewachter, Ilse, Gellersen, Helena M., Low, Audrey, Lourida, Ilianna, Machado, Luiza, Madan, Christopher R., Malpetti, Maura, Mejia, Jhony, Michopoulou, Sofia, Muñoz‐Neira, Carlos, Pepys, Jack, Peres, Marion, Phillips, Veronica, Ramanan, Siddharth, Tamburin, Stefano, Tantiangco, Hanz M., Thakur, Lokendra, Tomassini, Alessandro, Vipin, Ashwati, Tang, Eugene, Newby, Danielle, Ranson, Janice M., Llewellyn, David J., Veldsman, Michele, Rittman, Timothy

“…Introduction Artificial intelligence (AI) and neuroimaging offer new opportunities for diagnosis and prognosis of dementia. Methods We systematically reviewed…”
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Attention-deficit/hyperactivity disorder and ischemic stroke: A Mendelian randomization study by Du, Runming, Zhou, Yi, You, Chong, Liu, Kevin, King, Daniel A, Liang, Zhi-Sheng, Ranson, Janice M, Llewellyn, David J, Huang, Jie, Zhang, Zhenyu

“…Background: Observational studies have found an association between attention-deficit/hyperactivity disorder (ADHD) and ischemic stroke. Aims: The purpose of…”
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Artificial intelligence for dementia—Applied models and digital health by Lyall, Donald M., Kormilitzin, Andrey, Lancaster, Claire, Sousa, Jose, Petermann‐Rocha, Fanny, Buckley, Christopher, Harshfield, Eric L., Iveson, Matthew H., Madan, Christopher R., McArdle, Ríona, Newby, Danielle, Orgeta, Vasiliki, Tang, Eugene, Tamburin, Stefano, Thakur, Lokendra S., Lourida, Ilianna, Llewellyn, David J., Ranson, Janice M.

“…INTRODUCTION The use of applied modeling in dementia risk prediction, diagnosis, and prognostics will have substantial public health benefits, particularly as…”
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Predictors of dementia misclassification when using brief cognitive assessments by Ranson, Janice M, Kuźma, Elżbieta, Hamilton, William, Muniz-Terrera, Graciela, Langa, Kenneth M, Llewellyn, David J

“…Brief cognitive assessments can result in false-positive and false-negative dementia misclassification. We aimed to identify predictors of misclassification by…”
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Artificial intelligence for dementia prevention by Newby, Danielle, Orgeta, Vasiliki, Marshall, Charles R., Lourida, Ilianna, Albertyn, Christopher P., Tamburin, Stefano, Raymont, Vanessa, Veldsman, Michele, Koychev, Ivan, Bauermeister, Sarah, Weisman, David, Foote, Isabelle F., Bucholc, Magda, Leist, Anja K., Tang, Eugene Y. H., Tai, Xin You, Llewellyn, David J., Ranson, Janice M.

“…INTRODUCTION A wide range of modifiable risk factors for dementia have been identified. Considerable debate remains about these risk factors, possible…”
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Artificial intelligence for dementia genetics and omics by Bettencourt, Conceicao, Skene, Nathan, Bandres‐Ciga, Sara, Anderson, Emma, Winchester, Laura M., Foote, Isabelle F., Schwartzentruber, Jeremy, Botia, Juan A., Nalls, Mike, Singleton, Andrew, Schilder, Brian M., Humphrey, Jack, Marzi, Sarah J., Toomey, Christina E., Kleifat, Ahmad Al, Harshfield, Eric L., Garfield, Victoria, Sandor, Cynthia, Keat, Samuel, Tamburin, Stefano, Frigerio, Carlo Sala, Lourida, Ilianna, Ranson, Janice M., Llewellyn, David J.

“…Genetics and omics studies of Alzheimer's disease and other dementia subtypes enhance our understanding of underlying mechanisms and pathways that can be…”
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Artificial intelligence for neurodegenerative experimental models by Marzi, Sarah J., Schilder, Brian M., Nott, Alexi, Frigerio, Carlo Sala, Willaime‐Morawek, Sandrine, Bucholc, Magda, Hanger, Diane P., James, Charlotte, Lewis, Patrick A., Lourida, Ilianna, Noble, Wendy, Rodriguez‐Algarra, Francisco, Sharif, Jalil‐Ahmad, Tsalenchuk, Maria, Winchester, Laura M., Yaman, Ümran, Yao, Zhi, Ranson, Janice M., Llewellyn, David J.

“…INTRODUCTION Experimental models are essential tools in neurodegenerative disease research. However, the translation of insights and drugs discovered in model…”
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Vitamin D and Memory Decline: Two Population-Based Prospective Studies by Kuźma, Elżbieta, Soni, Maya, Littlejohns, Thomas J, Ranson, Janice M, van Schoor, Natasja M, Deeg, Dorly J H, Comijs, Hannie, Chaves, Paulo H M, Kestenbaum, Bryan R, Kuller, Lewis H, Lopez, Oscar L, Becker, James T, Langa, Kenneth M, Henley, William E, Lang, Iain A, Ukoumunne, Obioha C, Llewellyn, David J

“…Vitamin D deficiency has been linked with dementia risk, cognitive decline, and executive dysfunction. However, the association with memory remains largely…”
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The Deep Dementia Phenotyping (DEMON) Network: A global platform for innovation using data science and artificial intelligence by Ranson, Janice M, Khleifat, Ahmad Al, Lyall, Donald M, Newby, Danielle, Winchester, Laura M, Proitsi, Petroula, Veldsman, Michele, Rittman, Timothy, Marzi, Sarah, Yao, Zhi, Skene, Nathan, Bettencourt, Conceição, Kormilitzin, Andrey, Foote, Isabelle F, Golborne, Cecilia, Lourida, Ilianna, Bucholc, Magda, Tang, Eugene, Oxtoby, Neil P, Bagshaw, Peter, Walker, Zuzana, Everson, Richard, Ballard, Clive G, van Duijn, Cornelia M, Langa, Kenneth M, MacLeod, Malcolm, Rockwood, Kenneth, Llewellyn, David J

“…Background The increasing availability of large high‐dimensional data from experimental medicine, population‐based and clinical cohorts, clinical trials, and…”
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