Search Results - "Ransick, Andrew"

Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney by Ransick, Andrew, Lindström, Nils O., Liu, Jing, Zhu, Qin, Guo, Jin-Jin, Alvarado, Gregory F., Kim, Albert D., Black, Hannah G., Kim, Junhyong, McMahon, Andrew P.

“…Chronic kidney disease affects 10% of the population with notable differences in ethnic and sex-related susceptibility to kidney injury and disease. Kidney…”
Get full text

Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney by Lindström, Nils O, Guo, Jinjin, Kim, Albert D, Tran, Tracy, Guo, Qiuyu, De Sena Brandine, Guilherme, Ransick, Andrew, Parvez, Riana K, Thornton, Matthew E, Baskin, Laurence, Grubbs, Brendan, McMahon, Jill A, Smith, Andrew D, McMahon, Andrew P

“…Cellular interactions among nephron, interstitial, and collecting duct progenitors drive mammalian kidney development. In mice, Six2 nephron progenitor cells…”
Get full text

In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes by Tran, Tracy, Lindström, Nils O., Ransick, Andrew, De Sena Brandine, Guilherme, Guo, Qiuyu, Kim, Albert D., Der, Balint, Peti-Peterdi, Janos, Smith, Andrew D., Thornton, Matthew, Grubbs, Brendan, McMahon, Jill A., McMahon, Andrew P.

“…The renal corpuscle of the kidney comprises a glomerular vasculature embraced by podocytes and supported by mesangial myofibroblasts, which ensure plasma…”
Get full text

Cis-regulatory logic driving glial cells missing: Self-sustaining circuitry in later embryogenesis by Ransick, Andrew, Davidson, Eric H.

“…The glial cells missing (gcm) regulatory gene of the sea urchin Strongylocentrotus purpuratus is first expressed in veg2 daughter cells as the genomic target…”
Get full text

Diversification of oral and aboral mesodermal regulatory states in pregastrular sea urchin embryos by Materna, Stefan C., Ransick, Andrew, Li, Enhu, Davidson, Eric H.

“…Specification of the non-skeletogenic mesoderm (NSM) in sea urchin embryos depends on Delta signaling. Signal reception leads to expression of regulatory genes…”
Get full text

A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells by Guo, Qiuyu, Kim, Albert, Li, Bin, Ransick, Andrew, Bugacov, Helena, Chen, Xi, Lindström, Nils, Brown, Aaron, Oxburgh, Leif, Ren, Bing, McMahon, Andrew P

“…The canonical Wnt pathway transcriptional co-activator β-catenin regulates self-renewal and differentiation of mammalian nephron progenitor cells (NPCs). We…”
Get full text

cis-regulatory processing of Notch signaling input to the sea urchin glial cells missing gene during mesoderm specification by Ransick, Andrew, Davidson, Eric H.

“…The glial cells missing regulatory gene of Strongylocentrotus purpuratus ( spgcm) was proposed earlier to be the genomic target of Delta/Notch (D/N) signaling…”
Get full text

Detection of mRNA by In Situ Hybridization and RT-PCR by Ransick, Andrew

“…This chapter provides an overview of several approaches currently being used that rely on messenger RNA (mRNA) from a relatively small amount of starting…”
Get full text

Correction: A β-catenin-driven switch in TCF/LEF transcription factor binding to DNA target sites promotes commitment of mammalian nephron progenitor cells by Guo, Qiuyu, Kim, Albert D, Li, Bin, Ransick, Andrew, Bugacov, Helena, Chen, Xi, Lindström, Nils O, Brown, Aaron, Oxburgh, Leif, Ren, Bing, McMahon, Andrew P

Get full text

A Genomic Regulatory Network for Development by Davidson, Eric H., Rast, Jonathan P., Oliveri, Paola, Ransick, Andrew, Calestani, Cristina, Yuh, Chiou-Hwa, Minokawa, Takuya, Amore, Gabriele, Hinman, Veronica, Arenas-Mena, César, Otim, Ochan, Brown, C. Titus, Livi, Carolina B., Lee, Pei Yun, Revilla, Roger, Rust, Alistair G., Pan, Zheng jun, Schilstra, Maria J., Peter J. C. Clarke, Arnone, Maria I., Rowen, Lee, Cameron, R. Andrew, McClay, David R., Hood, Leroy, Bolouri, Hamid

“…Development of the body plan is controlled by large networks of regulatory genes. A gene regulatory network that controls the specification of endoderm and…”
Get full text

Specification of cell fate in the sea urchin embryo: summary and some proposed mechanisms by Davidson, E H, Cameron, R A, Ransick, A

“…An early set of blastomere specifications occurs during cleavage in the sea urchin embryo, the result of both conditional and autonomous processes, as proposed…”
Get full text

New Early Zygotic Regulators Expressed in Endomesoderm of Sea Urchin Embryos Discovered by Differential Array Hybridization by Ransick, Andrew, Rast, Jonathan P., Minokawa, Takuya, Calestani, Cristina, Davidson, Eric H.

“…Genes that are upregulated by LiCl treatment of sea urchin embryos and/or downregulated by injection into the egg of mRNA encoding an internal fragment of…”
Get full text

Recovery of Developmentally Defined Gene Sets from High-Density cDNA Macroarrays by Rast, Jonathan P, Amore, Gabriele, Calestani, Cristina, Livi, Carolina B, Ransick, Andrew, Davidson, Eric H

“…New technologies for isolating differentially expressed genes from large arrayed cDNA libraries are reported. These methods can be used to identify genes that…”
Get full text

An Evolutionary Constraint: Strongly Disfavored Class of Change in DNA Sequence during Divergence of Cis-Regulatory Modules by Cameron, R. Andrew, Chow, Suk Hen, Berney, Kevin, Chiu, Tsz-Yeung, Yuan, Qiu-Autumn, Krämer, Alexander, Helguero, Argelia, Ransick, Andrew, Yun, Mirong, Davidson, Eric H.

“…The DNA of functional cis-regulatory modules displays extensive sequence conservation in comparisons of genomes from modestly distant species. Patches of…”
Get full text

Micromeres are required for normal vegetal plate specification in sea urchin embryos by Ransick, A, Davidson, E H

“…Vegetal plate specification was assessed in S. purpuratus embryos after micromere deletions at the 4th, 5th and 6th cleavages, by assaying expression of the…”
Get full text

A Complete Second Gut Induced by Transplanted Micromeres in the Sea Urchin Embryo by Ransick, Andrew, Davidson, Eric H.

“…Founder cells for most early lineages of the sea urchin embryo are probably specified through inductive intercellular interactions. It is shown here that a…”
Get full text

Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis by Lindström, Nils O., De Sena Brandine, Guilherme, Tran, Tracy, Ransick, Andrew, Suh, Gio, Guo, Jinjin, Kim, Albert D., Parvez, Riana K., Ruffins, Seth W., Rutledge, Elisabeth A., Thornton, Matthew E., Grubbs, Brendan, McMahon, Jill A., Smith, Andrew D., McMahon, Andrew P.

“…Mammalian nephrons arise from a limited nephron progenitor pool through a reiterative inductive process extending over days (mouse) or weeks (human) of kidney…”
Get full text

CBFβ is a facultative Runx partner in the sea urchin embryo by Robertson, Anthony J, Dickey-Sims, Carrie, Ransick, Andrew, Rupp, Dawn E, McCarthy, John J, Coffman, James A

“…Abstract Background Runx proteins are developmentally important metazoan transcription factors that form a heterodimeric complex with the non-homologous…”
Get full text

Spatial transcriptional mapping of the human nephrogenic program by Lindström, Nils O., Sealfon, Rachel, Chen, Xi, Parvez, Riana K., Ransick, Andrew, De Sena Brandine, Guilherme, Guo, Jinjin, Hill, Bill, Tran, Tracy, Kim, Albert D., Zhou, Jian, Tadych, Alicja, Watters, Aaron, Wong, Aaron, Lovero, Elizabeth, Grubbs, Brendan H., Thornton, Matthew E., McMahon, Jill A., Smith, Andrew D., Ruffins, Seth W., Armit, Chris, Troyanskaya, Olga G., McMahon, Andrew P.

“…Congenital abnormalities of the kidney and urinary tract are among the most common birth defects, affecting 3% of newborns. The human kidney forms around a…”
Get full text

Late Specification of Veg1Lineages to Endodermal Fate in the Sea Urchin Embryo by Ransick, Andrew, Davidson, Eric H.

“…Single blastomeres of the sixth-cleavage veg1and veg2tiers ofStrongylocentrotus purpuratusembryos were labeled with DiI lineage tracer, and the disposition of…”
Get full text