Search Results - "Ranković, Vladan"

Near physiological spectral selectivity of cochlear optogenetics by Dieter, Alexander, Duque-Afonso, Carlos J., Rankovic, Vladan, Jeschke, Marcus, Moser, Tobias

“…Cochlear implants (CIs) electrically stimulate spiral ganglion neurons (SGNs) and partially restore hearing to half a million CI users. However, wide current…”
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High frequency neural spiking and auditory signaling by ultrafast red-shifted optogenetics by Mager, Thomas, Lopez de la Morena, David, Senn, Verena, Schlotte, Johannes, D´Errico, Anna, Feldbauer, Katrin, Wrobel, Christian, Jung, Sangyong, Bodensiek, Kai, Rankovic, Vladan, Browne, Lorcan, Huet, Antoine, Jüttner, Josephine, Wood, Phillip G., Letzkus, Johannes J., Moser, Tobias, Bamberg, Ernst

“…Optogenetics revolutionizes basic research in neuroscience and cell biology and bears potential for medical applications. We develop mutants leading to a…”
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Utility of red‐light ultrafast optogenetic stimulation of the auditory pathway by Bali, Burak, Lopez de la Morena, David, Mittring, Artur, Mager, Thomas, Rankovic, Vladan, Huet, Antoine Tarquin, Moser, Tobias

“…Optogenetic stimulation of spiral ganglion neurons (SGNs) in the ear provides a future alternative to electrical stimulation used in current cochlear implants…”
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Encoding and Transducing the Synaptic or Extrasynaptic Origin of NMDA Receptor Signals to the Nucleus by Karpova, Anna, Mikhaylova, Marina, Bera, Sujoy, Bär, Julia, Reddy, Pasham Parameshwar, Behnisch, Thomas, Rankovic, Vladan, Spilker, Christina, Bethge, Philipp, Sahin, Jale, Kaushik, Rahul, Zuschratter, Werner, Kähne, Thilo, Naumann, Michael, Gundelfinger, Eckart D., Kreutz, Michael R.

“…The activation of N-methyl-D-aspartate-receptors (NMDARs) in synapses provides plasticity and cell survival signals, whereas NMDARs residing in the neuronal…”
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μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve by Dieter, Alexander, Klein, Eric, Keppeler, Daniel, Jablonski, Lukasz, Harczos, Tamas, Hoch, Gerhard, Rankovic, Vladan, Paul, Oliver, Jeschke, Marcus, Ruther, Patrick, Moser, Tobias

“…Electrical cochlear implants (eCIs) partially restore hearing and enable speech comprehension to more than half a million users, thereby re‐connecting deaf…”
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Viral rhodopsins 1 are an unique family of light-gated cation channels by Zabelskii, Dmitrii, Alekseev, Alexey, Kovalev, Kirill, Rankovic, Vladan, Balandin, Taras, Soloviov, Dmytro, Bratanov, Dmitry, Savelyeva, Ekaterina, Podolyak, Elizaveta, Volkov, Dmytro, Vaganova, Svetlana, Astashkin, Roman, Chizhov, Igor, Yutin, Natalia, Rulev, Maksim, Popov, Alexander, Eria-Oliveira, Ana-Sofia, Rokitskaya, Tatiana, Mager, Thomas, Antonenko, Yuri, Rosselli, Riccardo, Armeev, Grigoriy, Shaitan, Konstantin, Vivaudou, Michel, Büldt, Georg, Rogachev, Andrey, Rodriguez-Valera, Francisco, Kirpichnikov, Mikhail, Moser, Tobias, Offenhäusser, Andreas, Willbold, Dieter, Koonin, Eugene, Bamberg, Ernst, Gordeliy, Valentin

“…Phytoplankton is the base of the marine food chain as well as oxygen and carbon cycles and thus plays a global role in climate and ecology. Nucleocytoplasmic…”
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Autochthonous infection with Ehrlichia Canis and Hepatozoon Canis in dogs from Serbia by Sukara, Ratko, Andrić, Nenad, Andrić, Jelena Francuski, Mihaljica, Darko, Veinović, Gorana, Ranković, Vladan, Tomanović, Snežana

“…Background The epidemiological status concerning many canine tick‐borne diseases (TBDs) in Serbia is still insufficiently known. Objectives Our study aimed to…”
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Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants by Huet, Antoine Tarquin, Dombrowski, Tobias, Rankovic, Vladan, Thirumalai, Anupriya, Moser, Tobias

“…Optogenetic stimulation of type I spiral ganglion neurons (SGNs) promises an alternative to the electrical stimulation by current cochlear implants (CIs) for…”
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Cabp2-Gene Therapy Restores Inner Hair Cell Calcium Currents and Improves Hearing in a DFNB93 Mouse Model by Oestreicher, David, Picher, Maria Magdalena, Rankovic, Vladan, Moser, Tobias, Pangrsic, Tina

“…Clinical management of auditory synaptopathies like other genetic hearing disorders is currently limited to the use of hearing aids or cochlear implants…”
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Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness by Rankovic, Vladan, Vogl, Christian, Dörje, Nele M, Bahader, Iman, Duque-Afonso, Carlos J, Thirumalai, Anupriya, Weber, Thomas, Kusch, Kathrin, Strenzke, Nicola, Moser, Tobias

“…Hearing impairment is the most common sensory disorder in humans. So far, rehabilitation of profoundly deaf subjects relies on direct stimulation of the…”
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ADP-ribosylation factor 6 regulates mu-opioid receptor trafficking and signaling via activation of phospholipase D2 by Rankovic, Marija, Jacob, Lea, Rankovic, Vladan, Brandenburg, Lars-Ove, Schröder, Helmut, Höllt, Volker, Koch, Thomas

“…Endocytosis of the mu-opioid receptor (MOPr) has been shown to play a protective role against the development of tolerance to opioid drugs by facilitating…”
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Modulation of calcium-dependent inactivation of L-type Ca2+ channels via β-adrenergic signaling in thalamocortical relay neurons by Rankovic, Vladan, Landgraf, Peter, Kanyshkova, Tatyana, Ehling, Petra, Meuth, Sven G, Kreutz, Michael R, Budde, Thomas, Munsch, Thomas

“…Neuronal high-voltage-activated (HVA) Ca(2+) channels are rapidly inactivated by a mechanism that is termed Ca(2+)-dependent inactivation (CDI). In this study…”
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Intracellular Ca2+ release-dependent inactivation of Ca2+ currents in thalamocortical relay neurons by Rankovic, Vladan, Ehling, Petra, Coulon, Philippe, Landgraf, Peter, Kreutz, Michael R., Munsch, Thomas, Budde, Thomas

“…Neuronal Ca2+ channels are rapidly inactivated by a mechanism that is termed Ca2+‐dependent inactivation (CDI). In this study we investigated the influence of…”
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Application of Targeting-Optimized Chronos for Stimulation of the Auditory Pathway by Huet, Antoine Tarquin, Rankovic, Vladan

“…In the last 15 years, optogenetics has revolutionized the life sciences and enabled studies of complex biological systems such as the brain. Applying…”
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Toward the Optical Cochlear Implant by Dombrowski, Tobias, Rankovic, Vladan, Moser, Tobias

“…When hearing fails, cochlear implants (CIs) provide open speech perception to most of the currently half a million CI users. CIs bypass the defective sensory…”
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Ultrafast optogenetic stimulation of the auditory pathway by targeting‐optimized Chronos by Keppeler, Daniel, Merino, Ricardo Martins, Lopez de la Morena, David, Bali, Burak, Huet, Antoine Tarquin, Gehrt, Anna, Wrobel, Christian, Subramanian, Swati, Dombrowski, Tobias, Wolf, Fred, Rankovic, Vladan, Neef, Andreas, Moser, Tobias

“…Optogenetic tools, providing non‐invasive control over selected cells, have the potential to revolutionize sensory prostheses for humans. Optogenetic…”
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Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders by GRABRUCKER, Stefanie, JANNETTI, Linda, KREUTZ, Michael R, EHRET, Günter, BOECKERS, Tobias M, GRABRUCKER, Andreas M, ECKERT, Matti, GAUB, Simone, CHHABRA, Resham, PFAENDER, Stefanie, MANGUS, Katharina, PARAMESHWAR PASHAM REDDY, RANKOVIC, Vladan, SCHMEISSER, Michael J

“…Proteins of the ProSAP/Shank family act as major organizing scaffolding elements within the postsynaptic density of excitatory synapses. Deletions, mutations…”
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Network pharmacology for antiepileptogenesis: Tolerability of multitargeted drug combinations in nonepileptic vs. post-status epilepticus mice by Klee, Rebecca, Töllner, Kathrin, Rankovic, Vladan, Römermann, Kerstin, Schidlitzki, Alina, Bankstahl, Marion, Löscher, Wolfgang

“…Highlights • Prevention of epilepsy in patients at risk is a major unmet clinical need. • Epilepsy is a network phenomenon, so that a single drug can probably…”
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Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice by Bali, Burak, Gruber-Dujardin, Eva, Kusch, Kathrin, Rankovic, Vladan, Moser, Tobias

“…AAV-mediated optogenetic neural stimulation has become a clinical approach for restoring function in sensory disorders and feasibility for hearing restoration…”
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A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy by Schidlitzki, Alina, Twele, Friederike, Klee, Rebecca, Waltl, Inken, Römermann, Kerstin, Bröer, Sonja, Meller, Sebastian, Gerhauser, Ingo, Rankovic, Vladan, Li, Dandan, Brandt, Claudia, Bankstahl, Marion, Töllner, Kathrin, Löscher, Wolfgang

“…Epilepsy may arise following acute brain insults, but no treatments exist that prevent epilepsy in patients at risk. Here we examined whether a combination of…”
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