Search Results - "Rank, Doug"

Evaluation of protein engineering and process optimization approaches to enhance antibody drug manufacturability by Conley, Greg P., Viswanathan, Malini, Hou, Ying, Rank, Doug L., Lindberg, Allison P., Cramer, Steve M., Ladner, Robert C., Nixon, Andrew E., Chen, Jie

“…A potent single digit picomolar fully human monoclonal antibody (hMAb) inhibitor with a high degree of specificity to the antigen of interest was identified…”
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A series of pharmacokinetic studies of ceftaroline fosamil in select populations: Normal subjects, healthy elderly subjects, and subjects with renal impairment or end-stage renal disease requiring hemodialysis by Riccobene, Todd, Jakate, Abhijeet, Rank, Doug

“…Ceftaroline fosamil is a parenteral cephalosporin indicated for the treatment of acute bacterial skin and skin structure infections and community‐acquired…”
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Randomized Trial of Ceftazidime-Avibactam vs Meropenem for Treatment of Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia (REPROVE): Analyses per US FDA-Specified End Points by Torres, Antoni, Rank, Doug, Melnick, David, Rekeda, Ludmyla, Chen, Xiang, Riccobene, Todd, Critchley, Ian A, Lakkis, Hassan D, Taylor, Dianna, Talley, Angela K

“…Hospital-acquired and ventilator-associated pneumonia (HAP/VAP; nosocomial pneumonia) due to Gram-negative pathogens are associated with significant morbidity…”
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Phase 3, Randomized, Double-blind Noninferiority (NI) Study of Ceftazidime–Avibactam (CAZ-AVI) vs. Meropenem (MER) in the Treatment of Patients with Hospital-acquired Bacterial Pneumonia and Ventilator-associated Bacterial Pneumonia (HABP/VABP): Analyses of the REPROVE Study per US FDA Endpoints by Torres, Antoni, Rank, Doug, Rekeda, Ludmyla, Chen, Xiang, Riccobene, Todd, Critchley, Ian, Lakkis, Hassan, Melnick, David, Chow, Joseph W, Taylor, Dianna, Laud, Peter J, Talley, Angela K

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Novel small scale TFF cell retention device for perfusion cell culture systems by Martin, Chris S, Padilla-Zamudio, Jorge, Rank, Doug, McInnis, Patrick, Kozlov, Mikhail, Reynolds, Sarah, Parella, Joe, Madrid, Lee

“…Perfusion processes have traditionally been used for the generation of unstable proteins in cell culture systems. The use of perfusion for production of stable…”
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