Search Results - "Ranjan, Bobby"

scConsensus: combining supervised and unsupervised clustering for cell type identification in single-cell RNA sequencing data by Ranjan, Bobby, Schmidt, Florian, Sun, Wenjie, Park, Jinyu, Honardoost, Mohammad Amin, Tan, Joanna, Arul Rayan, Nirmala, Prabhakar, Shyam

“…Clustering is a crucial step in the analysis of single-cell data. Clusters identified in an unsupervised manner are typically annotated to cell types based on…”
Get full text

DUBStepR is a scalable correlation-based feature selection method for accurately clustering single-cell data by Ranjan, Bobby, Sun, Wenjie, Park, Jinyu, Mishra, Kunal, Schmidt, Florian, Xie, Ronald, Alipour, Fatemeh, Singhal, Vipul, Joanito, Ignasius, Honardoost, Mohammad Amin, Yong, Jacy Mei Yun, Koh, Ee Tzun, Leong, Khai Pang, Rayan, Nirmala Arul, Lim, Michelle Gek Liang, Prabhakar, Shyam

“…Feature selection (marker gene selection) is widely believed to improve clustering accuracy, and is thus a key component of single cell clustering pipelines…”
Get full text

Systematic immune cell dysregulation and molecular subtypes revealed by single-cell RNA-seq of subjects with type 1 diabetes by Honardoost, Mohammad Amin, Adinatha, Andreas, Schmidt, Florian, Ranjan, Bobby, Ghaeidamini, Maryam, Arul Rayan, Nirmala, Gek Liang Lim, Michelle, Joanito, Ignasius, Xiao Xuan Lin, Quy, Rajagopalan, Deepa, Qi Mok, Shi, Hwang, You Yi, Larbi, Anis, Khor, Chiea Chuen, Foo, Roger, Boehm, Bernhard Otto, Prabhakar, Shyam

“…Type 1 diabetes mellitus (T1DM) is a prototypic endocrine autoimmune disease resulting from an immune-mediated destruction of pancreatic insulin-secreting…”
Get full text

Lineage-dependent gene expression programs influence the immune landscape of colorectal cancer by Lee, Hae-Ock, Hong, Yourae, Etlioglu, Hakki Emre, Cho, Yong Beom, Pomella, Valentina, Van den Bosch, Ben, Vanhecke, Jasper, Verbandt, Sara, Hong, Hyekyung, Min, Jae-Woong, Kim, Nayoung, Eum, Hye Hyeon, Qian, Junbin, Boeckx, Bram, Lambrechts, Diether, Tsantoulis, Petros, De Hertogh, Gert, Chung, Woosung, Lee, Taeseob, An, Minae, Shin, Hyun-Tae, Joung, Je-Gun, Jung, Min-Hyeok, Ko, Gunhwan, Wirapati, Pratyaksha, Kim, Seok Hyung, Kim, Hee Cheol, Yun, Seong Hyeon, Tan, Iain Bee Huat, Ranjan, Bobby, Lee, Woo Yong, Kim, Tae-You, Choi, Jung Kyoon, Kim, Young-Joon, Prabhakar, Shyam, Tejpar, Sabine, Park, Woong-Yang

“…Immunotherapy for metastatic colorectal cancer is effective only for mismatch repair-deficient tumors with high microsatellite instability that demonstrate…”
Get full text

Composite mathematical modeling of calcium signaling behind neuronal cell death in Alzheimer's disease by Ranjan, Bobby, Chong, Ket Hing, Zheng, Jie

“…Alzheimer's disease (AD) is a progressive neurological disorder, recognized as the most common cause of dementia affecting people aged 65 and above. AD is…”
Get full text

Paternal microbiome perturbations impact offspring fitness by Argaw-Denboba, Ayele, Schmidt, Thomas S. B., Di Giacomo, Monica, Ranjan, Bobby, Devendran, Saravanan, Mastrorilli, Eleonora, Lloyd, Catrin T., Pugliese, Danilo, Paribeni, Violetta, Dabin, Juliette, Pisaniello, Alessandra, Espinola, Sergio, Crevenna, Alvaro, Ghosh, Subhanita, Humphreys, Neil, Boruc, Olga, Sarkies, Peter, Zimmermann, Michael, Bork, Peer, Hackett, Jamie A.

“…The gut microbiota operates at the interface of host–environment interactions to influence human homoeostasis and metabolic networks 1 – 4 . Environmental…”
Get full text

RCA2: a scalable supervised clustering algorithm that reduces batch effects in scRNA-seq data by Schmidt, Florian, Ranjan, Bobby, Lin, Quy Xiao Xuan, Krishnan, Vaidehi, Joanito, Ignasius, Honardoost, Mohammad Amin, Nawaz, Zahid, Venkatesh, Prasanna Nori, Tan, Joanna, Rayan, Nirmala Arul, Ong, Sin Tiong, Prabhakar, Shyam

“…Abstract The transcriptomic diversity of cell types in the human body can be analysed in unprecedented detail using single cell (SC) technologies. Unsupervised…”
Get full text