Search Results - "Ranjan, Ajenthen G."
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Performance of a dual-hormone closed-loop system versus insulin-only closed-loop system in adolescents with type 1 diabetes. A single-blind, randomized, controlled, crossover trial
Published in Frontiers in endocrinology (Lausanne) (23-01-2023)“…To assess the efficacy and safety of a dual-hormone (DH [insulin and glucagon]) closed-loop system compared to a single-hormone (SH [insulin only]) closed-loop…”
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Sensor-Based Glucose Metrics during Different Diet Compositions in Type 1 Diabetes-A Randomized One-Week Crossover Trial
Published in Nutrients (01-01-2024)“…By reducing carbohydrate intake, people with type 1 diabetes may reduce fluctuations in blood glucose, but the evidence in this area is sparse. The aim of this…”
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Glycemia Around Exercise in Adults with Type 1 Diabetes Using Automated and Nonautomated Insulin Delivery Pumps: A Switch Pilot Trial
Published in Diabetes technology & therapeutics (01-04-2023)“…In an in-patient switch study, 10 adults with type 1 diabetes (T1D) performed 45 min of moderate-intensity exercise on 2 occasions: (1) when using their usual…”
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A collaborative comparison of international pediatric diabetes registries
Published in Pediatric diabetes (01-09-2022)“…Background An estimated 1.1 million children and adolescents aged under 20 years have type 1 diabetes worldwide. Principal investigators from seven…”
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Effect of adjunctive glucose-lowering drugs on body weight in people with type 1 diabetes: a systematic review and network meta-analysis protocol
Published in BMJ open (14-11-2020)“…IntroductionObesity increases the risk of comorbidities and diabetes-related complications and, consequently, efforts to prevent and reduce excess weight in…”
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Time spent in hypoglycemia is comparable when the same amount of exercise is performed 5 or 2 days weekly: a randomized crossover study in people with type 1 diabetes
Published in BMJ open diabetes research & care (01-01-2021)“…IntroductionPeople with type 1 diabetes are recommended to exercise regularly. However, limited evidence exists on how frequency and duration of exercise…”
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Changes in the lipidome in type 1 diabetes following low carbohydrate diet: Post‐hoc analysis of a randomized crossover trial
Published in Endocrinology, diabetes & metabolism (01-04-2021)“…Aims Lipid metabolism might be compromised in type 1 diabetes, and the understanding of lipid physiology is critically important. This study aimed to compare…”
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Low-Dose Dasiglucagon Versus Oral Glucose for Prevention of Insulin-Induced Hypoglycemia in People With Type 1 Diabetes: A Phase 2, Randomized, Three-Arm Crossover Study
Published in Diabetes care (02-06-2022)“…To compare the efficacy of low-dose subcutaneous dasiglucagon with oral glucose for prevention of insulin-induced hypoglycemia in people with type 1 diabetes…”
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Improved Time in Range Over 1 Year Is Associated With Reduced Albuminuria in Individuals With Sensor-Augmented Insulin Pump-Treated Type 1 Diabetes
Published in Diabetes care (01-11-2020)“…To investigate the association between treatment-induced change in continuous glucose monitoring (CGM) time in range (TIR) and albuminuria in persons with type…”
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Pen-administered low-dose dasiglucagon vs usual care for prevention and treatment of non-severe hypoglycaemia in people with type 1 diabetes during free-living conditions: a Phase II, randomised, open-label, two-period crossover trial
Published in Diabetologia (01-07-2023)“…Aims/hypothesis Consumption of excess carbohydrates to manage hypoglycaemia can lead to rebound hyperglycaemia and promote weight gain. The objective of this…”
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257-OR: Pen-Administered Low-Dose Dasiglucagon vs. Usual Care for Prevention and Treatment of Nonsevere Hypoglycemia in People with Type 1 Diabetes during Free-Living Conditions: A Phase 2, Randomized, Two-Period, Crossover Outpatient Study
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Objective: To evaluate the efficacy, safety and feasibility of pen-administered low-dose dasiglucagon for prevention and treatment of non-severe hypoglycemia…”
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Glucagon for hypoglycaemia treatment in type 1 diabetes
Published in Diabetes/metabolism research and reviews (01-07-2021)“…To achieve strict glycaemic control and avoid chronic diabetes complications, individuals with type 1 diabetes (T1D) are recommended to follow an intensive…”
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Glucose Monitoring Metrics in Individuals With Type 1 Diabetes Using Different Treatment Modalities: A Real-World Observational Study
Published in Diabetes care (01-11-2023)“…OBJECTIVE This study aimed to investigate the association between continuous glucose monitoring (CGM)-derived glycemic metrics and different insulin treatment…”
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Effects of a Low-Carbohydrate-High-Protein Pre-Exercise Meal in Type 1 Diabetes—a Randomized Crossover Trial
Published in The journal of clinical endocrinology and metabolism (21-12-2023)“…Abstract Context Current guidelines for exercise-related glucose management focus on reducing bolus and/or basal insulin doses and considering carbohydrate…”
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129-LB: A Comparison of CGM Metrics in People with Type 1 Diabetes Treated with Different Insulin Modalities
Published in Diabetes (New York, N.Y.) (20-06-2023)“…Background: There is a lack of real-world data comparing CGM data across different insulin treatment modalities. This study examined the association between…”
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Automated Insulin Delivery in Adults With Type 1 Diabetes and Suboptimal HbA1c During Prior Use of Insulin Pump and Continuous Glucose Monitoring: A Randomized Controlled Trial
Published in Journal of diabetes science and technology (11-04-2024)“…Automated insulin delivery (AID) systems offer promise in improving glycemic outcomes for individuals with type 1 diabetes. However, data on those who struggle…”
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215-OR: Performance of a Dual Hormone Closed-Loop System vs. an Insulin-Only Closed-Loop System during Challenging Inpatient Conditions: A Single-Blinded Randomized Controlled Crossover Trial
Published in Diabetes (New York, N.Y.) (01-06-2021)“…Objective: To assess the efficacy and safety of an insulin-glucagon dual-hormone (DH) compared with an insulin-only single-hormone (SH) closed-loop system…”
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The effect of preceding glucose decline rate on low‐dose glucagon efficacy in individuals with type 1 diabetes: A randomized crossover trial
Published in Diabetes, obesity & metabolism (01-04-2021)“…Identifying determinants of low‐dose glucagon efficacy is important to optimise its utilization for prevention and treatment of hypoglycaemia in individuals…”
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Automated Insulin Delivery in Adults With Type 1 Diabetes and Suboptimal HbA 1c During Prior Use of Insulin Pump and Continuous Glucose Monitoring: A Randomized Controlled Trial
Published in Journal of diabetes science and technology (11-04-2024)“…Automated insulin delivery (AID) systems offer promise in improving glycemic outcomes for individuals with type 1 diabetes. However, data on those who struggle…”
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Cardiovascular Autonomic Neuropathy Is Associated With Increased Glucose Variability in People With Type 1 Diabetes
Published in Diabetes care (01-10-2022)“…OBJECTIVE We investigated the association between the cardiovascular autonomic neuropathy (CAN) diagnosis and glucose variability (GV) in type 1 diabetes…”
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