Search Results - "Rania, Soudy"

Short amylin receptor antagonist peptides improve memory deficits in Alzheimer’s disease mouse model by Soudy, Rania, Kimura, Ryoichi, Patel, Aarti, Fu, Wen, Kaur, Kamaljit, Westaway, David, Yang, Jing, Jhamandas, Jack

“…Recent evidence supports involvement of amylin and the amylin receptor in the pathogenesis of Alzheimer’s disease (AD). We have previously shown that amylin…”
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Author Correction: Short amylin receptor antagonist peptides improve memory deficits in Alzheimer’s disease mouse model by Soudy, Rania, Kimura, Ryoichi, Patel, Aarti, Fu, Wen, Kaur, Kamaljit, Westaway, David, Yang, Jing, Jhamandas, Jack

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Genetic Depletion of Amylin/Calcitonin Receptors Improves Memory and Learning in Transgenic Alzheimer’s Disease Mouse Models by Patel, Aarti, Kimura, Ryoichi, Fu, Wen, Soudy, Rania, MacTavish, David, Westaway, David, Yang, Jing, Davey, Rachel A., Zajac, Jeffrey D., Jhamandas, Jack H.

“…Based upon its interactions with amyloid β peptide (Aβ), the amylin receptor, a class B G protein-coupled receptor (GPCR), is a potential modulator of…”
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Extracellular vesicles enriched with amylin receptor are cytoprotective against the Aß toxicity in vitro by Soudy, Rania, Kimura, Ryoichi, Fu, Wen, Patel, Aarti, Jhamandas, Jack

“…Extracellular vesicles (EVs) are double membrane structures released by all cell types with identified roles in the generation, transportation, and degradation…”
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Amylin Receptor: A Potential Therapeutic Target for Alzheimer’s Disease by Fu, Wen, Patel, Aarti, Kimura, Ryoichi, Soudy, Rania, Jhamandas, Jack H

“…Alzheimer’s disease (AD) is a progressive neurodegenerative disorder, characterized by senile plaques constituting extracellular deposits of β-amyloid (Aβ)…”
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Role of microglial amylin receptors in mediating beta amyloid (Aβ)-induced inflammation by Fu, Wen, Vukojevic, Vlatka, Patel, Aarti, Soudy, Rania, MacTavish, David, Westaway, David, Kaur, Kamaljit, Goncharuk, Valeri, Jhamandas, Jack

“…Neuroinflammation in the brain consequent to activation of microglia is viewed as an important component of Alzheimer's disease (AD) pathology. Amyloid beta…”
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Electrochemical Characterization of Protein Adsorption onto YNGRT-Au and VLGXE-Au Surfaces by Trzeciakiewicz, Hanna, Esteves-Villanueva, Jose, Soudy, Rania, Kaur, Kamaljit, Martic-Milne, Sanela

“…The adsorption of the proteins CD13, mucin and bovine serum albumin on VLGXE-Au and YNGRT-Au interfaces was monitored by electrochemical impedance spectroscopy…”
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Design and Evaluation of Gemini Surfactant-Based Lipoplexes Modified with Cell-Binding Peptide for Targeted Gene Therapy in Melanoma Model by Mohammed-Saeid, Waleed, Soudy, Rania, Tikoo, Richa, Kaur, Kamaljit, Verrall, Ronald E, Badea, Ildiko

“…Purpose Achieving successful gene therapy requires delivery of a gene vector specifically to the targeted tissue with efficient expression and a good safety…”
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Modified cantilever arrays improve sensitivity and reproducibility of nanomechanical sensing in living cells by Patil, Samadhan B., Al-Jehani, Rajai M., Etayash, Hashem, Turbe, Valerian, Jiang, Keren, Bailey, Joe, Al-Akkad, Walid, Soudy, Rania, Kaur, Kamaljit, McKendry, Rachel A., Thundat, Thomas, Ndieyira, Joseph W.

“…Mechanical signaling involved in molecular interactions lies at the heart of materials science and biological systems, but the mechanisms involved are poorly…”
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Cyclic AC253, a novel amylin receptor antagonist, improves cognitive deficits in a mouse model of Alzheimer's disease by Soudy, Rania, Patel, Aarti, Fu, Wen, Kaur, Kamaljit, MacTavish, David, Westaway, David, Davey, Rachel, Zajac, Jeffrey, Jhamandas, Jack

“…Abstract Introduction Amylin receptor serves as a portal for the expression of deleterious effects of amyloid β-protein (Aβ), a key pathologic hallmark of…”
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Modulation of Hypoxia-Induced Chemoresistance to Polymeric Micellar Cisplatin: The Effect of Ligand Modification of Micellar Carrier Versus Inhibition of the Mediators of Drug Resistance by Soleymani Abyaneh, Hoda, Soleimani, Amir Hassan, Vakili, Mohammad Reza, Soudy, Rania, Kaur, Kamaljit, Cuda, Francesco, Tavassoli, Ali, Lavasanifar, Afsaneh

“…Hypoxia can induce chemoresistance, which is a significant clinical obstacle in cancer therapy. Here, we assessed development of hypoxia-induced…”
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Novel Peptide–Doxorubucin Conjugates for Targeting Breast Cancer Cells Including the Multidrug Resistant Cells by Soudy, Rania, Chen, Christopher, Kaur, Kamaljit

“…The efficacy of chemotherapeutic doxorubucin (Dox) in cancer treatment is limited by two main factors, nonspecific toxicity and the emergence of tumor…”
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Breast Cancer Targeting Peptide Binds Keratin 1: A New Molecular Marker for Targeted Drug Delivery to Breast Cancer by Soudy, Rania, Etayash, Hashem, Bahadorani, Kamran, Lavasanifar, Afsaneh, Kaur, Kamaljit

“…The biomarkers or receptors expressed on cancer cells and the targeting ligands with high binding affinity for biomarkers play a key role in early detection…”
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Engineered breast tumor targeting peptide ligand modified liposomal doxorubicin and the effect of peptide density on anticancer activity by Shahin, Mostafa, Soudy, Rania, Aliabadi, Hamidreza M, Kneteman, Norman, Kaur, Kamaljit, Lavasanifar, Afsaneh

“…Abstract This study aimed to develop actively targeted liposomal formulations of doxorubicin (DOX) using an engineered breast tumor targeting peptide ligand,…”
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Proteolytically Stable Cancer Targeting Peptides with High Affinity for Breast Cancer Cells by Soudy, Rania, Gill, Avneet, Sprules, Tara, Lavasanifar, Afsaneh, Kaur, Kamaljit

“…Cancer cell targeting peptides have emerged as a highly efficient approach for selective delivery of chemotherapeutics and diagnostics to different cancer…”
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NGR Peptide Ligands for Targeting CD13/APN Identified through Peptide Array Screening Resemble Fibronectin Sequences by Soudy, Rania, Ahmed, Sahar, Kaur, Kamaljit

“…Peptides containing the Asn-Gly-Arg (NGR) motif are known to bind CD13 isoforms expressed in tumor vessels and have been widely used for tumor targeting…”
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Correction to Novel Peptide–Doxorubucin Conjugates for Targeting Breast Cancer Cells Including the Multidrug Resistant Cells by Soudy, Rania, Chen, Christopher, Kaur, Kamaljit

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Proteolytically Stable Cyclic Decapeptide for Breast Cancer Cell Targeting by Raghuwanshi, Yogita, Etayash, Hashem, Soudy, Rania, Paiva, Igor, Lavasanifar, Afsaneh, Kaur, Kamaljit

“…Starting with a previously reported linear breast cancer targeting decapeptide WxEAAYQkFL, here we report the synthesis of a novel cyclic peptide analogue…”
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Synthetic peptides derived from the sequence of a lasso peptide microcin J25 show antibacterial activity by Soudy, Rania, Wang, Liru, Kaur, Kamaljit

“…Microcin J25 (MccJ25) is a plasmid-encoded, ribosomally synthesized antibacterial peptide with a unique lasso structure. The lasso structure, produced with the…”
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Traceable PEO-poly(ester) micelles for breast cancer targeting: The effect of core structure and targeting peptide on micellar tumor accumulation by Garg, Shyam M., Paiva, Igor M., Vakili, Mohammad R., Soudy, Rania, Agopsowicz, Kate, Soleimani, Amir H., Hitt, Mary, Kaur, Kamaljit, Lavasanifar, Afsaneh

“…Traceable poly(ethylene oxide)-poly(ester) micelles were developed through chemical conjugation of a near-infrared (NIR) dye to the poly(ester) end by click…”
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