Search Results - "Rani, M. R. Preetha"

ICAM-1 Deletion Using CRISPR/Cas9 Protects the Brain from Traumatic Brain Injury-Induced Inflammatory Leukocyte Adhesion and Transmigration Cascades by Attenuating the Paxillin/FAK-Dependent Rho GTPase Pathway by Saikia, Bibhuti Ballav, Bhowmick, Saurav, Malat, Anitha, Preetha Rani, M R, Thaha, Almas, Abdul-Muneer, P M

“…Intercellular adhesion molecule-1 (ICAM-1) is identified as an initiator of neuroinflammatory responses that lead to neurodegeneration and cognitive and…”
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Bilobalide abates inflammation, insulin resistance and secretion of angiogenic factors induced by hypoxia in 3T3-L1 adipocytes by controlling NF-κB and JNK activation by Priyanka, A, Sindhu, G, Shyni, GL, Preetha Rani, MR, Nisha, VM, Raghu, KG

“…Obesity leads to inflammation and insulin resistance in adipose tissue. Hypoxia, observed in obese adipose tissue is suggested as a major cause of inflammation…”
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Glucotoxicity results in apoptosis in H9c2 cells via alteration in redox homeostasis linked mitochondrial dynamics and polyol pathway and possible reversal with cinnamic acid by Anupama, Nair, Preetha Rani, M.R., Shyni, G.L., Raghu, K.G.

“…Several mechanisms have been proposed for the heart dysfunction during hyperglycemia. The aim of the present in vitro study is to elucidate the role of…”
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Endoplasmic reticulum stress: A master regulator of metabolic syndrome by Mohan, Sreelekshmi, R, Preetha Rani M., Brown, Lindsay, Ayyappan, Prathapan, G, Raghu K.

“…Endoplasmic reticulum (ER) stress, a change in the ER homeostasis, leads to initiation of the unfolded protein response (UPR). The primary functions of the UPR…”
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In vitro and in vivo studies reveal the beneficial effects of chlorogenic acid against ER stress mediated ER-phagy and associated apoptosis in the heart of diabetic rat by Preetha Rani, M.R., Salin Raj, P., Nair, Anupama, Ranjith, S., Rajankutty, K., Raghu, K.G.

“…Endoplasmic reticulum (ER) and associated signaling pathways are involved in diabetic cardiomyopathy (DCM) however, detailed studies are not available. The…”
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Ferulic acid attenuates high glucose-induced MAM alterations via PACS2/IP3R2/FUNDC1/VDAC1 pathway activating proapoptotic proteins and ameliorates cardiomyopathy in diabetic rats by Salin Raj, P., Nair, Anupama, Preetha Rani, M.R., Rajankutty, K., Ranjith, S., Raghu, K.G.

“…Diabetic cardiomyopathy (DCM) is one of the severe complications of diabetes with no known biomarkers for early detection. Mitochondria-associated endoplasmic…”
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Cinnamic acid is beneficial to diabetic cardiomyopathy via its cardioprotective, anti‐inflammatory, anti‐dyslipidemia, and antidiabetic properties by Nair, Anupama, Preetha Rani, M. R., Salin Raj, Palayyan, Ranjit, S., Rajankutty, K., Raghu, K. G.

“…Diabetes‐related health issues are increasing day by day in public, and diabetic cardiomyopathy (DCM) is one serious issue among them. There is a lack of…”
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Insulin resistance in 3T3-L1 adipocytes by TNF-α is improved by punicic acid through upregulation of insulin signalling pathway and endocrine function, and downregulation of proinflammatory cytokines by Anusree, S.S., Sindhu, G., Preetha Rani, M.R., Raghu, K.G.

“…Insulin resistance (IR) has become a major threat to public health due to its role in metabolic syndrome. Inflammation associated with IR is an interesting…”
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Chlorogenic acid attenuates glucotoxicity in H9c2 cells via inhibition of glycation and PKC α upregulation and safeguarding innate antioxidant status by Preetha Rani, M.R., Anupama, Nair, Sreelekshmi, Mohan, Raghu, K.G.

“…[Display omitted] A series of cardiovascular complications associated with hyperglycemia is a critical threat to the diabetic population. Here we elucidate the…”
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Discovery of novel microRNAs and their pathogenic responsive target genes in mild traumatic brain injury by Bhowmick, Saurav, Rani, M. R. Preetha, Singh, Shubham, Abdul-Muneer, P. M.

“…MicroRNAs (miRNAs) are non-coding RNA molecules that function in RNA silencing and post-transcriptional regulation of gene expression. They are profound…”
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Corrigendum to < “Glucotoxicity results in apoptosis in H9c2 cells via alteration in redox homeostasis linked mitochondrial dynamics and polyol pathway and possible reversal with cinnamic acid”> <[Toxicology in Vitro 53 (2018) 178–192]> by Anupama, Nair, Preetha Rani, M.R., Shyni, G.L., Raghu, K.G.

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Parmotrema tinctorum exhibits antioxidant, antiglycation and inhibitory activities against aldose reductase and carbohydrate digestive enzymes: an in vitro study by Salin Raj, P., Prathapan, A., Sebastian, Jomon, Antony, Antu K., Riya, Mariam Philip, Rani, M.R. Preetha, Biju, H., Priya, S., Raghu, K.G.

“…This study evaluated the inhibitory potential of ethyl acetate extract of Parmotrema tinctorum (PTEE), an edible lichen, against aldose reductase (AR) and…”
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Corrigendum to “Chlorogenic acid attenuates glucotoxicity in H9c2 cells via inhibition of glycation and PKC α upregulation and safeguarding innate antioxidant status” [Biomed. Pharmacother. 100 (2018) 467–477] by M.R, Preetha Rani, Nair, Anupama, Mohan, Sreelekshmi, K.G, Raghu

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