Search Results - "Rangel, Luciana Pereira"
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1
Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
Published in Molecules (Basel, Switzerland) (18-02-2020)“…This review aims to explore the potential of resveratrol, a polyphenol stilbene, and beta-lapachone, a naphthoquinone, as well as their derivatives, in the…”
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2
Bioactive Compounds and Metabolites from Grapes and Red Wine in Breast Cancer Chemoprevention and Therapy
Published in Molecules (Basel, Switzerland) (01-08-2020)“…Phytochemicals and their metabolites are not considered essential nutrients in humans, although an increasing number of well-conducted studies are linking…”
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3
Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells
Published in The Journal of biological chemistry (14-06-2019)“…Dysfunctional p53 formation and activity can result from aberrant expression and subcellular localization of distinct p53 isoforms or aggregates. Endometrial…”
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4
Methoxy Stilbenes as Potent, Specific, Untransported, and Noncytotoxic Inhibitors of Breast Cancer Resistance Protein
Published in ACS chemical biology (17-02-2012)“…The ABCG2 multidrug transporter is known to confer cancer cell multidrug resistance by causing the efflux of anticancer drugs; therefore, selective inhibitors…”
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In vivo evaluation of time-dependent antithrombotic effect of rivaroxaban-loaded poly(lactic-co-glycolic acid)/sodium lauryl sulfate or didodecyl dimethylammonium bromide nanoparticles in Wistar rats
Published in European journal of pharmaceutics and biopharmaceutics (01-09-2023)“…[Display omitted] •RVX-loaded PLGA/SLS or DMAB nanoparticles were successfully prepared using the nanoprecipitation method.•RVX encapsulated in SLS or DMAB…”
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6
Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion
Published in Molecules (Basel, Switzerland) (16-11-2022)“…Prion Diseases or Transmissible Spongiform Encephalopathies are neurodegenerative conditions associated with a long incubation period and progressive clinical…”
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7
Naphthoquinone-Quinolone Hybrids with Antitumor Effects on Breast Cancer Cell Lines-From the Synthesis to 3D-Cell Culture Effects
Published in International journal of molecular sciences (12-06-2024)“…Breast cancer stands as one of the foremost cause of cancer-related deaths globally, characterized by its varied molecular subtypes. Each subtype requires a…”
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8
Evaluation of the effect of cafeteria diet on the kidney Na,K‐ATPase activity, and oxidative stress
Published in Journal of cellular biochemistry (01-11-2019)“…In this study, renal tissue, subdivided into the cortex and medulla of Wistar rats subjected to a cafeteria diet (CAF) for 24 days or to normal diet, was used…”
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9
Inhibitory effects of gallic acid ester derivatives on Saccharomyces cerevisiae multidrug resistance protein Pdr5p
Published in FEMS yeast research (01-05-2010)“…Overexpression of the Saccharomyces cerevisiae ABC transporter Pdr5p confers resistance to a range of structurally unrelated xenobiotics. This property allows…”
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10
New structure-activity relationships of chalcone inhibitors of breast cancer resistance protein: polyspecificity toward inhibition and critical substitutions against cytotoxicity
Published in Drug design, development and therapy (01-01-2013)“…Adenosine triphosphate-binding cassette subfamily G member 2 (ABCG2) plays a major role in cancer cell multidrug resistance, which contributes to low efficacy…”
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11
Inhibitory effects of gallic acid ester derivatives on Saccharomyces cerevisiae multidrug resistance protein Pdr5p
Published in FEMS yeast research (01-05-2010)“…Abstract Overexpression of the Saccharomyces cerevisiae ABC transporter Pdr5p confers resistance to a range of structurally unrelated xenobiotics. This…”
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12
Effect of different extracts from the Brazilian Atlantic Forest on the Pdr5p ATPase activity
Published in Revista brasileira de farmacognosia (01-03-2008)“…In the current study, we tested the effect of 27 plant extracts and fractions from different botanical families on the activity of Pdr5p from yeast plasma…”
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13
Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain
Published in The Journal of biological chemistry (02-06-2017)“…Inactivation of the tumor suppressor protein p53 by mutagenesis, chemical modification, protein-protein interaction, or aggregation has been associated with…”
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14
Prion protein-coated magnetic beads: Synthesis, characterization and development of a new ligands screening method
Published in Journal of Chromatography A (30-01-2015)“…•Prion protein was immobilized onto the surface of magnetic beads.•PrP-coated magnetic beads were characterized by fluorescence confocal microscopy.•Ligands…”
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15
Studies on the utilization of a thioaptamer for the rescue of p53 and its mutants
Published in The FASEB journal (01-04-2011)“…p53 is a tumor suppression protein that, among other functions, works as a transcription factor in response to different cellular stress signals, leading to…”
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