Search Results - "Rangel, Héctor Rafael"
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Sputnik V-Induced Antibodies against SARS-CoV-2 Variants during the Dissemination of the Gamma Variant in Venezuela
Published in Viruses (18-09-2024)“…The COVID-19 pandemic was characterized by the emergence and succession of SARS-CoV-2 variants able to evade the antibody response induced by natural infection…”
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Humoral Immunity across the SARS-CoV-2 Spike after Sputnik V (Gam-COVID-Vac) Vaccination
Published in Antibodies (Basel) (11-05-2024)“…SARS-CoV-2 vaccines have contributed to attenuating the burden of the COVID-19 pandemic by promoting the development of effective immune responses, thus…”
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Inverse Molecular Docking Study of NS3-Helicase and NS5-RNA Polymerase of Zika Virus as Possible Therapeutic Targets of Ligands Derived from Marcetia taxifolia and Its Implications to Dengue Virus
Published in ACS omega (09-03-2021)“…Dengue and Zika are two mosquito-borne diseases of great impact on public health around the world in tropical and subtropical countries. DENV and ZIKV belong…”
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Lasting SARS-CoV-2 specific IgG Antibody response in health care workers from Venezuela, 6 months after vaccination with Sputnik V
Published in International journal of infectious diseases (01-09-2022)“…•We measured RBD-IgG levels in Sputnik V vaccinated 6 months after vaccination.•The GMT of RBD-IgG antibodies in a COVID-19 naïve cohort was 327 BAU/ml.•The…”
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Molecular characteristics and replication mechanism of dengue, zika and chikungunya arboviruses, and their treatments with natural extracts from plants: An updated review
Published in EXCLI journal (01-01-2019)“…Viruses transmitted by arthropods (arboviruses) are the etiological agents of several human diseases with worldwide distribution; including dengue (DENV), zika…”
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Neutralization of Different Variants of SARS-CoV-2 by a F(ab')2 Preparation from Sera of Horses Immunized with the Viral Receptor Binding Domain
Published in Antibodies (Basel) (07-12-2023)“…The Receptor Binding Domain (RBD) of SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is the functional region of the viral Spike protein (S),…”
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Omicron SARS-CoV-2 Variant Spike Protein Shows an Increased Affinity to the Human ACE2 Receptor: An In Silico Analysis
Published in Pathogens (Basel) (31-12-2021)“…The rise of SARS-CoV-2 variants, with changes that could be related to an increased virus pathogenicity, have received the interest of the scientific and…”
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Immunoglobulin G antibody response to the Sputnik V vaccine: previous SARS-CoV-2 seropositive individuals may need just one vaccine dose
Published in International journal of infectious diseases (01-10-2021)“…•A longitudinal study to determine the immoglobulin G response after Sputnik V vaccine•SARS-CoV-2 seronegative vaccinees showed a primary response upon…”
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HIV-1 and GBV-C co-infection in Venezuela
Published in Journal of infection in developing countries (14-07-2014)“…Co-infection with GB virus C (GBV-C) in patients infected with human immunodeficiency virus 1 (HIV-1) has been associated with prolonged survival. The aim of…”
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Deletion, insertion and stop codon mutations in vif genes of HIV-1 infecting slow progressor patients
Published in Journal of infection in developing countries (30-08-2009)“…Variable progression towards AIDS has been described and has been related to viral and host factors. Around 10% of the HIV-1 infected patients are slow…”
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Prevalence of antiretroviral drug resistance among treatment-naive and treated HIV-infected patients in Venezuela
Published in Memórias do Instituto Oswaldo Cruz (01-05-2009)“…An in-house, low-cost method was developed to determine the genotypic resistance of immunodeficiency virus type 1 (HIV-1) isolates. All 179 Venezuelan isolates…”
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Antiviral activity of flavonoids present in aerial parts of Marcetia taxifolia against Hepatitis B virus, Poliovirus, and Herpes Simplex Virus in vitro
Published in EXCLI journal (01-01-2019)“…is a neotropical plant present in South America and it has been evaluated in several biological models due to the presence of active metabolites. Nevertheless,…”
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Neutralization of Different Variants of SARS-CoV-2 by a F2 Preparation from Sera of Horses Immunized with the Viral Receptor Binding Domain
Published in Antibodies (Basel) (01-12-2023)“…The Receptor Binding Domain (RBD) of SARS-CoV-2, the virus responsible for the COVID-19 pandemic, is the functional region of the viral Spike protein (S),…”
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Role of changes in SARS-CoV-2 spike protein in the interaction with the human ACE2 receptor: An in silico analysis
Published in EXCLI journal (01-01-2020)“…Many human viral diseases are a consequence of a zoonotic event. Some of the diseases caused by these zoonotic events have affected millions of people around…”
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Unrevealing sequence and structural features of novel coronavirus using in silico approaches: The main protease as molecular target
Published in EXCLI journal (01-01-2020)“…Direct-acting antivirals are effective tools to control viral infections. SARS-CoV-2 is a coronavirus associated with the epidemiological outbreak in late…”
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