Search Results - "Ranganathan, Prabha"
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An update on methotrexate pharmacogenetics in rheumatoid arthritis
Published in Pharmacogenomics (01-04-2008)“…Rheumatoid arthritis (RA) is a systemic inflammatory disorder that mainly affects the joints. When left untreated, the disease can result in irreversible joint…”
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Methotrexate pharmacogenetics in rheumatoid arthritis: a status report
Published in Pharmacogenomics (01-02-2013)“…Methotrexate (MTX), an antifolate drug, is the first-line disease-modifying agent for the treatment of rheumatoid arthritis (RA) worldwide. MTX has excellent…”
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Development and validation of lupus nephritis case definitions using United States veterans affairs electronic health records
Published in Lupus (01-03-2021)“…Objective International Classification of Diseases (ICD) codes are commonly used to identify patients with rare diseases in electronic health records (EHRs)…”
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Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis
Published in Journal of rheumatology (01-04-2008)“…OBJECTIVE: Research has examined the association of folate-dependent gene polymorphisms with methotrexate (MTX) toxicity in racially homogenous patients with…”
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Tumor Necrosis Factor Inhibition and Head and Neck Cancer Recurrence and Death in Rheumatoid Arthritis
Published in PloS one (23-11-2015)“…The objective of this retrospective cohort study was to determine the effect of tumor necrosis factor inhibitor (TNFi) therapy on the risk of head and neck…”
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A Potential Role for Stress-Induced Microbial Alterations in IgA-Associated Irritable Bowel Syndrome with Diarrhea
Published in Cell reports. Medicine (20-10-2020)“…Stress is a known trigger for flares of inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS); however, this process is not well understood…”
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Neoplastic and Paraneoplastic Vasculitis, Vasculopathy, and Hypercoagulability
Published in Rheumatic diseases clinics of North America (01-11-2011)“…Rheumatologists are often consulted regarding both typical and atypical vasculitides, vasculopathies, and hypercoagulability. It is important to keep in mind…”
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Monitoring methotrexate toxicity: Are we being over-vigilant?
Published in BMJ (Online) (30-05-2023)Get more information
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Immunologic rheumatic disorders
Published in Journal of allergy and clinical immunology (01-02-2010)“…We provide the basics for clinicians who might be called on to consider the diagnosis of diseases such as systemic lupus erythematosus (SLE) or rheumatoid…”
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Successful use of rituximab for hydralazine-induced anti-neutrophil cytoplasmic antibodies-associated vasculitis
Published in Saudi journal of kidney diseases and transplantation (2019)“…Hydralazine is a commonly used anti-hypertensive medication. It can, however, contribute to the development of autoimmunity, in the form of drug-induced lupus…”
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Biomarkers of response to TNF inhibition in RA
Published in Nature reviews. Rheumatology (01-08-2015)“…The quest for new biomarkers of response to therapies in rheumatoid arthritis (RA), particularly to TNF inhibitors, continues. Two recent studies add to this…”
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Differential risk of herpes zoster infection with biologic agent use in rheumatoid arthritis: comment on the article by Yun et al
Published in Arthritis care & research (2010) (01-07-2015)Get full text
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Skin Induration in a Patient With Aplastic Anemia
Published in Arthritis care & research (01-07-2018)Get full text
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ABC transporter genes and methotrexate response in rheumatoid arthritis
Published in Journal of rheumatology (01-04-2013)Get full text
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Genetic variants influencing response to methotrexate in juvenile idiopathic arthritis and rheumatoid arthritis
Published in Rheumatology international (01-01-2016)Get full text
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Herpes zoster infection risk in patients with rheumatoid arthritis on tumour necrosis factor inhibitors
Published in Annals of the rheumatic diseases (01-05-2013)Get more information
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Rheumatoid arthritis: Biomarkers of response to TNF inhibition in RA
Published in Nature reviews. Rheumatology (01-08-2015)Get full text
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The challenges of methotrexate pharmacogenetics in rheumatoid arthritis
Published in Pharmacogenomics (01-03-2012)Get more information
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Pharmacogenetics; implications for therapy in rheumatic diseases
Published in Nature reviews. Rheumatology (01-05-2015)Get full text
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Pharmacogenetics of therapies in rheumatoid arthritis: An update
Published in Best practice & research. Clinical rheumatology (20-07-2024)“…Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory arthritis. Despite many treatment advances, achieving remission or low-disease activity in RA…”
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