Search Results - "Ranea, J. A."

Regulatory cross-talk of mouse liver polyamine and methionine metabolic pathways: a systemic approach to its physiopathological consequences by Correa-Fiz, F., Reyes-Palomares, A., Fajardo, I., Melgarejo, E., Gutiérrez, A., García-Ranea, J. A., Medina, M. A., Sánchez-Jiménez, F.

“…Both polyamines and methionine derivatives are nitrogen compounds directly related to the regulation of gene expression. In silico predictions and experimental…”
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Systems biology approaches to enhance our understanding of drug hypersensitivity reactions by Perkins, J. R., Barrionuevo, E., Ranea, J. A., Blanca, M., Cornejo-Garcia, J. A.

“…Summary Hypersensitivity drug reactions (HDRs) encompass a wide spectrum of unpredictable clinical entities. They represent an important health problem,…”
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p23 and HSP20/α-crystallin proteins define a conserved sequence domain present in other eukaryotic protein families by Garcia-Ranea, J.A, Mirey, Gladys, Camonis, Jacques, Valencia, Alfonso

“…We identified families of proteins characterized by the presence of a domain similar to human p23 protein, which include proteins such as Sgt1, involved in the…”
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Systematic computational prediction of protein interaction networks by Lees, J G, Heriche, J K, Morilla, I, Ranea, J A, Orengo, C A

“…Determining the network of physical protein associations is an important first step in developing mechanistic evidence for elucidating biological pathways…”
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Immune Recognition of Swine Vesicular Disease Virus Structural Proteins: Novel Antigenic Regions That Are Not Exposed in the Capsid by Jiménez-Clavero, M.A., Douglas, A., Lavery, T., Garcia-Ranea, J.A., Ley, V.

“…Swine vesicular disease virus (SVDV) is an enterovirus of the Picornaviridae family that belongs to the coxsackievirus B group. A number of antigenic sites…”
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Distribution and functional diversification of the ras superfamily in Saccharomyces cerevisiae by Garcia-Ranea, Juan Antonio, Valencia, Alfonso

“…The recent availability of the full Saccharomyces cerevisiae genome sequence offers a first opportunity to analyze the composition, function and evolution of…”
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Effector Recognition by the Small GTP-binding Proteins Ras and Ral by Bauer, B, Mirey, G, Vetter, I R, García-Ranea, J A, Valencia, A, Wittinghofer, A, Camonis, J H, Cool, R H

“…The Ral effector protein RLIP76 (also called RIP/RalBP1) binds to Ral·GTP via a region that shares no sequence homology with the Ras-binding domains of the…”
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Model of the Ran-RCC1 Interaction using Biochemical and Docking Experiments by Azuma, Yoshiaki, Renault, Louis, Garcı́a-Ranea, Juan A., Valencia, Alfonso, Nishimoto, Takeharu, Wittinghofer, Alfred

“…RCC1, the regulator of chromosome condensation, is the guanine nucleotide exchange factor (GEF) for the nuclear Ras-like GTP-binding protein Ran. Its structure…”
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Characterization of neutralization sites on the circulating variant of swine vesicular disease virus (SVDV): a new site is shared by SVDV and the related coxsackie B5 virus by Borrego, B, Carra, E, Garcia-Ranea, J.A, Brocchi, E

“…Using a panel of new monoclonal antibodies (mAbs), five neutralizing, conformation-dependent sites have been identified on the antigenic variant of swine…”
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RhoGAPs and RhoGDIs, (His)stories of two families by Zalcman, G, Dorseuil, O, Garcia-Ranea, J A, Gacon, G, Camonis, J

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Genome evolution: Micro(be)-economics by Ranea, J A G

“…The recent sequencing of the genomes of two of the most abundant pelagic bacteria, Pelagibacter ubique and Prochlorococcus marinus, have revealed that they…”
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Search for ancient patterns in protein sequences by Thode, G, García-Ranea, J A, Jimenez, J

“…Proteins of related functions are often similar in sequence, reflecting a common phylogenetic origin. Proteins with no known homology are probably diversified…”
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TSEMA: interactive prediction of protein pairings between interacting families by Izarzugaza, José M.G, Juan, David, Pons, Carles, Ranea, Juan A.G, Valencia, Alfonso, Pazos, Florencio

“…An entire family of methodologies for predicting protein interactions is based on the observed fact that families of interacting proteins tend to have similar…”
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The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors by VARGIU, Pierfrancesco, DE ABAJO, Ricardo, GARCIA-RANEA, Juan Antonio, VALENCIA, Alfonso, SANTISTEBAN, Pilar, CRESPO, Piero, BERNAL, Juan

“…The Ras homolog enriched in striatum, Rhes, is the product of a thyroid hormone-regulated gene during brain development. Rhes and the dexamethasone-induced…”
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Evolution of Protein Superfamilies and Bacterial Genome Size by Ranea, Juan A.G., Buchan, Daniel W.A., Thornton, Janet M., Orengo, Christine A.

“…We present the structural annotation of 56 different bacterial species based on the assignment of genes to 816 evolutionary superfamilies in the CATH domain…”
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Heparan sulphate mediates swine vesicular disease virus attachment to the host cell by Escribano-Romero, E, Jimenez-Clavero, M.A, Gomes, P, Garcia-Ranea, J.A, Ley, V

“…1 Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Dep. Biotecnología, Ctra Coruña Km 7.5, 28040 Madrid, Spain 2 Serveis…”
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Mapping of linear epitopes on the capsid proteins of swine vesicular disease virus using monoclonal antibodies by Borrego, B, Garcia-Ranea, J.A, Douglas, A, Brocchi, E

“…The antigenic linear map of swine vesicular disease virus (SVDV) has been studied using a repertoire of monoclonal antibodies (mAbs) raised against a…”
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