Search Results - "Rane, Vipul"

Liquid chromatographic separation and thermodynamic investigation of lorcaserin hydrochloride enantiomers on immobilized amylose–based chiral stationary phase by Wani, Dattatraya V., Rane, Vipul P., Mokale, Santosh N.

“…A novel liquid chromatographic method was developed for enantiomeric separation of lorcaserin hydrochloride on Chiralpak IA column containing chiral stationary…”
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Synthesis and control of process-related impurities in the β-lactamase inhibitor drug substance zidebactam by Pund, Amit A., Rane, Vipul P., Raut, Vivek T., Ahirrao, Vinod K., Yeole, Ravindra D., Joshi, Sanjeev, Bhavsar, Satish, Rafeeq, Mohammad, Yadav, Ramprasad, Merwade, Arvind Y.

“…Zidebactam is a novel extended spectrum β-lactamase inhibitor (ESBLI). It's combination with cefepime (WCK 5222) is in phase III clinical studies. Five process…”
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Impurity Profiling of a Novel Anti-MRSA Antibacterial Drug: Alalevonadifloxacin by Patil, Kiran R, Rane, Vipul P, Ahirrao, Vinod K, Yeole, Ravindra D

“…Abstract Alalevonadifloxacin (ALA, formerly described as WCK 2349) is a novel antibacterial drug developed to treat infections caused by Gram-positive…”
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Stereo-retentive synthesis of (5S)-5-benzyloxycarbonyl-5-tert-butoxycarbonylamino-2-oxo-pentylide-dimethylsulfoxonium, a key intermediate of a β-lactamase inhibitor by Pund, Amit, Rane, Vipul, Pursani, Rajesh, Ahirrao, Vinod, Rafeeq, Mohammad, Yadav, Ram Prasad, Yeole, Ravindra, Merwade, Arvind

“…(5 S )-5-benzyloxycarbonyl-5-tert-butoxycarbonylamino-2-oxo-pentylide-dimethylsulfoxonium ( 4 ) is an important intermediate for the synthesis of β-lactamase…”
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Impurity Profiling of Novel Oxazolidinone Antibacterial Agent: WCK 4086 by Ahirrao, Vinod K., Patil, Rushikesh H., Pathan, Amin R., Patil, Kiran R., Rane, Vipul P., Yeole, Ravindra D.

“…WCK 4086 is new antibacterial drug being developed to treat infections caused by Gram positive bacteria. This study describes development of mass spectrometry…”
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Enantiomeric Separation and Thermodynamic Investigation of (R)-N-Tert-Butoxy Carbonyl-Piperidine-3-Carboxylic Acid Hydrazide, a Key Starting Material of Zidebactam by Rane, Vipul P, Ahirrao, Vinod K, More, Kiran B, Yeole, Ravindra D

“…A new selective, accurate and precise chiral high-performance liquid chromatography method for the separation of (R)-N-tert-butoxy…”
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Correction: Impurity Profiling of a Novel β-Lactam Enhancer: Zidebactam by Rane, Vipul P., Ahirrao, Vinod K., Patil, Kiran R., Jadhav, Rajiv A., Yeole, Ravindra D.

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Correction: Stereo-retentive synthesis of (5S)-5-benzyloxycarbonyl-5-tert-butoxycarbonylamino-2-oxo-pentylide-dimethylsulfoxonium, a key intermediate of a β-lactamase inhibitor by Pund, Amit, Rane, Vipul, Pursani, Rajesh, Ahirrao, Vinod, Rafeeq, Mohammad, Yadav, Ram Prasad, Yeole, Ravindra, Merwade, Arvind

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An Efficient HPLC–MS Method for Impurity Profile of Ertapenem by Jadhav, Rajiv A., Ahirrao, Vinod K., Pathan, Amin R., Patil, Kiran R., Rane, Vipul P., Yeole, Ravindra D.

“…A mass spectrometer compatible, reverse-phase high-performance liquid chromatography method capable to resolve twenty-six impurities and degradation products…”
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LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol by Rakibe, Uday, Tiwari, Ravi, Mahajan, Anand, Rane, Vipul, Wakte, Pravin

“…The aim of the present investigation was to demonstrate an approach involving use of liquid chromatography (LC) and liquid chromatography-mass spectrometry…”
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Impurity Profiling of a Novel β-Lactam Enhancer: Zidebactam by Rane, Vipul P., Ahirrao, Vinod K., Patil, Kiran R., Jadhav, Rajiv A., Yeole, Ravindra D.

“…Zidebactam (ZID) is a novel drug in clinical development; it potentiates the antibacterial activity of β-lactam antibiotics. Two reversed phase liquid…”
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Investigation on Impurity Profiling and Degradation Behavior of WCK 771 by Rane, Vipul P., Patil, Rushikesh H., Patil, Kiran R., Pathan, Amin R., Naik, Sukantakumar, Ahirrao, Vinod K., Jadhav, Rajiv A., Yeole, Ravindra D.

“…WCK 771 is a novel antibacterial drug recently launched in India for the treatment of acute bacterial skin and skin structure infections (ABSSSI). This report…”
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Identification of Monomethyl Sulfate and Sulfate Impurities in Zidebactam Using LC–MS and Application of Mixed-Mode Liquid Chromatography with Charged Aerosol Detection and Ion Chromatography for Quantification by Ahirrao, Vinod K., Rane, Vipul P., Patil, Kiran R., Jadhav, Rajiv A., Bhamare, Vijay S., Yadav, Dharamvir S., Yeole, Ravindra D.

“…Zidebactam (ZID), a novel β-lactam enhancer drug being developed to treat infections caused by Gram-negative bacteria, currently is in phase III clinical…”
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Identification and Quantification of Related Impurities of a Novel Ketolide Antibiotic Nafithromycin by Ahirrao, Vinod K., Rane, Vipul P., Patil, Kiran R., Jadhav, Rajiv A., Shinde, Vitthal A., Deshmukh, Vikas V., Dabhade, Sanjay K., Kale, Rajesh P., Gupta, Sunil V., Yeole, Ravindra D.

“…Nafithromycin (NFT, WCK 4873) is a novel antimicrobial drug being developed to treat infections caused by Gram-positive bacteria. It is a second-generation…”
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Efficient Synthesis of Potential Impurities in Levonadifloxacin (WCK 771) by Kilbile, Jaydeo T, Tamboli, Yasinalli, Rafeeq, Mohammad, Yadav, Ram Prasad, Rane, Vipul P, Bhamare, Vijay S, Merwade, Arvind Y

“…Levonadifloxacin (WCK 771) is a novel broad-spectrum anti-methicillin-resistant Staphylococcus aureus (MRSA) agent recently launched in India. Five process…”
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Liquid Chromatographic Separation and Thermodynamic Investigation of Ethyl Nipecotate Enantiomers on Immobilized Amylose-Based Chiral Stationary Phase by Rane, Vipul P, Ahirrao, Vinod K, Patil, Kiran R, Jadhav, Arjun B, More, Kiran B, Yeole, Ravindra D

“…Ethyl nipecotate enantiomers are widely used as chiral building blocks in the synthesis of drug substances. An efficient and economic chiral high-performance…”
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Identification of metabolites of novel Anti‐MRSA fluoroquinolone WCK 771 in mouse, rat, rabbit, dog, monkey and human urine using liquid chromatography tandem mass spectrometry by Yeole, Ravindra D., Rane, Vipul P., Ahirrao, Vinod K., Chavan, Rajesh P., Patel, Anasuya M., Deshpande, Prasad K., Patel, Mahesh V., Patil, Kiran R.

“…WCK 771 is an l‐arginine salt of levonadifloxacin (LND) being developed in intravenous dosage form and has recently completed a phase III trial in India. The…”
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Time-dependent selected reaction monitoring-based GC-MS/MS method for estimation of genotoxic impurities in new antibacterial agent: alalevonadifloxacin mesylate by Ahirrao, Vinod K., Jadhav, Rajiv A., Rane, Vipul P., Bhamare, Harshal R., Yeole, Ravindra D.

“…Alalevonadifloxacin mesylate (ALA), pro-drug of levonadifloxacin is a new antibiotic approved in India to treat infections caused by Gram-positive bacteria…”
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Development and Validation of the Chiral Liquid Chromatography Method for Separation of Enantiomeric Impurity in Novel Oxazolidinone Antibacterial Agent WCK 4086 by Ahirrao, Vinod K, Rane, Vipul P, Patil, Kiran R, Patil, Vijay J, Yeole, Ravindra D, Patel, Mahesh V

“…Abstract A highly stereo-specific liquid chromatographic method was developed and validated for the quantification of enantiomeric impurity (R-enantiomer) in…”
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Stability-Indicating LC Method for Analysis of Lornoxicam in the Dosage Form by Patil, Kiran R, Rane, Vipul P, Sangshetti, Jaiprakash N, Shinde, Devanand B

“…A simple, rapid, and precise method has been developed for quantitative analysis of lornoxicam (Lxm) in pharmaceutical dosage forms. Chromatographic separation…”
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