Search Results - "Randolph, Christopher E."

Neonatal Diet Impacts Circulatory miRNA Profile in a Porcine Model by Carr, Laura E, Bowlin, Anne K, Elolimy, Ahmed A, Byrum, Stephanie D, Washam, Charity L, Randolph, Christopher E, MacLeod, Stewart L, Yeruva, Laxmi

“…microRNAs (miRNAs) are conserved non-coding small nucleotide molecules found in nearly all species and breastmilk. miRNAs present in breastmilk are very stable…”
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Dietary soy protein reverses obesity-induced liver steatosis and alters fecal microbial composition independent of isoflavone level by Hakkak, Reza, Korourian, Soheila, Li, Wei, Spray, Beverly, Twaddle, Nathan C., Randolph, Christopher E., Børsheim, Elisabet, Robeson II, Michael S.

“…Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major public health concern that is exacerbated by the obesity pandemic…”
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Nox4 expression in osteo-progenitors controls bone development in mice during early life by Chen, Jin-Ran, Lazarenko, Oxana P., Blackburn, Michael L., Chen, Jennifer F., Randolph, Christopher E., Zabaleta, Jovanny, Schroder, Katrin, Pedersen, Kim B., Ronis, Martin J. J.

“…Tightly regulated and cell-specific NADPH-oxidases (Nox) represent one of the major sources of reactive oxygen species (ROS) signaling molecules that are…”
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Progression of diabetes is associated with changes in the ileal transcriptome and ileal‐colon morphology in the UC Davis Type 2 Diabetes Mellitus rat by Piccolo, Brian D., Graham, James L., Kang, Ping, Randolph, Christopher E., Shankar, Kartik, Yeruva, Laxmi, Fox, Renee, Robeson, Michael S., Moody, Becky, LeRoith, Tanya, Stanhope, Kimber L., Adams, Sean H., Havel, Peter J.

“…Deterioration in glucose homeostasis has been associated with intestinal dysbiosis, but it is not known how metabolic dysregulation alters the gastrointestinal…”
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Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats by Piccolo, Brian D, Graham, James L, Tabor-Simecka, Leslie, Randolph, Christopher E, Moody, Becky, Robeson, Michael S, Kang, Ping, Fox, Renee, Lan, Renny, Pack, Lindsay, Woford, Noah, Yeruva, Laxmi, LeRoith, Tanya, Stanhope, Kimber L, Havel, Peter J

“…IntroductionColonocyte oxidation of bacterial-derived butyrate has been reported to maintain synergistic obligate anaerobe populations by reducing colonocyte…”
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Formula Diet Alters the Ileal Metagenome and Transcriptome at Weaning and during the Postweaning Period in a Porcine Model by Elolimy, Ahmed A, Washam, Charity, Byrum, Stephanie, Chen, Celine, Dawson, Harry, Bowlin, Anne K, Randolph, Christopher E, Saraf, Manish K, Yeruva, Laxmi

“…Exclusive breastfeeding impacts the intestinal microbiome and is associated with a better immune function than is seen with milk formula (MF) feeding in…”
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Phenolic acids prevent sex-steroid deficiency-induced bone loss and bone marrow adipogenesis in mice by Caviness, Perry C., Lazarenko, Oxana P., Blackburn, Michael L., Chen, Jennifer F., Randolph, Christopher E., Zabaleta, Jovanny, Zhan, Fenghuang, Chen, Jin-Ran

“…Phenolic acids, such as hippuric acid (HA) and 3-(3-hydroxyphenyl) propionic acid (3-3-PPA), can be produced from microbiome digestion of polyphenols…”
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Durable Suppression of Acquired MEK Inhibitor Resistance in Cancer by Sequestering MEK from ERK and Promoting Antitumor T-cell Immunity by Hong, Aayoung, Piva, Marco, Liu, Sixue, Hugo, Willy, Lomeli, Shirley H, Zoete, Vincent, Randolph, Christopher E, Yang, Zhentao, Wang, Yan, Lee, Jordan J, Lo, Skylar J, Sun, Lu, Vega-Crespo, Agustin, Garcia, Alejandro J, Shackelford, David B, Dubinett, Steven M, Scumpia, Philip O, Byrum, Stephanie D, Tackett, Alan J, Donahue, Timothy R, Michielin, Olivier, Holmen, Sheri L, Ribas, Antoni, Moriceau, Gatien, Lo, Roger S

“…MAPK targeting in cancer often fails due to MAPK reactivation. MEK inhibitor (MEKi) monotherapy provides limited clinical benefits but may serve as a…”
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Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease by Li, Ming, Lyu, Chen, Huang, Manyan, Do, Catherine, Tycko, Benjamin, Lupo, Philip J, MacLeod, Stewart L, Randolph, Christopher E, Liu, Nianjun, Witte, John S, Hobbs, Charlotte A

“…Most congenital heart defects (CHDs) result from complex interactions among genetic susceptibilities, epigenetic modifications, and maternal environmental…”
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