Search Results - "Randall, Troy D"

The establishment of resident memory B cells in the lung requires local antigen encounter by Allie, S. Rameeza, Bradley, John E., Mudunuru, Uma, Schultz, Michael D., Graf, Beth A., Lund, Frances E., Randall, Troy D.

“…Memory B cells are found in lymphoid and non-lymphoid tissues, suggesting that some may be tissue-resident cells. Here we show that pulmonary influenza…”
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Interleukin-2 Inhibits Germinal Center Formation by Limiting T Follicular Helper Cell Differentiation by Ballesteros-Tato, André, León, Beatriz, Graf, Beth A., Moquin, Amy, Adams, Pamela Scott, Lund, Frances E., Randall, Troy D.

“…T follicular helper (Tfh) cells promote T cell-dependent humoral immune responses by providing T cell help to B cells and by promoting germinal center (GC)…”
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Specialized immune responses in the peritoneal cavity and omentum by Liu, Mingyong, Silva‐Sanchez, Aaron, Randall, Troy D., Meza‐Perez, Selene

“…The peritoneal cavity is a fluid filled space that holds most of the abdominal organs, including the omentum, a visceral adipose tissue that contains milky…”
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Inducible Bronchus-Associated Lymphoid Tissue: Taming Inflammation in the Lung by Hwang, Ji Young, Randall, Troy D, Silva-Sanchez, Aaron

“…Following pulmonary inflammation, leukocytes that infiltrate the lung often assemble into structures known as inducible Bronchus-Associated Lymphoid Tissue…”
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Pulmonary immunity to viruses by Allie, S Rameeza, Randall, Troy D

“…Mucosal surfaces, such as the respiratory epithelium, are directly exposed to the external environment and therefore, are highly susceptible to viral…”
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Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion by Nguyen, Doan C., Garimalla, Swetha, Xiao, Haopeng, Kyu, Shuya, Albizua, Igor, Galipeau, Jacques, Chiang, Kuang-Yueh, Waller, Edmund K., Wu, Ronghu, Gibson, Greg, Roberson, James, Lund, Frances E., Randall, Troy D., Sanz, Iñaki, Lee, F. Eun-Hyung

“…Human antibody-secreting cells (ASC) in peripheral blood are found after vaccination or infection but rapidly apoptose unless they migrate to the bone marrow…”
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Human Leukocyte Antigen Class I and II Knockout Human Induced Pluripotent Stem Cell-Derived Cells: Universal Donor for Cell Therapy by Mattapally, Saidulu, Pawlik, Kevin M, Fast, Vladimir G, Zumaquero, Esther, Lund, Frances E, Randall, Troy D, Townes, Tim M, Zhang, Jianyi

“…Background We aim to generate a line of "universal donor" human induced pluripotent stem cells (hi PSC s) that are nonimmunogenic and, therefore, can be used…”
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Development of secondary lymphoid organs by Randall, Troy D, Carragher, Damian M, Rangel-Moreno, Javier

“…Secondary lymphoid organs develop during embryogenesis or in the first few weeks after birth according to a highly coordinated series of interactions between…”
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IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs by Barone, Francesca, Nayar, Saba, Campos, Joana, Cloake, Thomas, Withers, David R., Toellner, Kai-Michael, Zhang, Yang, Fouser, Lynette, Fisher, Benjamin, Bowman, Simon, Rangel-Moreno, Javier, de la Luz Garcia-Hernandez, Maria, Randall, Troy D., Lucchesi, Davide, Bombardieri, Michele, Pitzalis, Costantino, Luther, Sanjiv A., Buckley, Christopher D.

“…The series of events leading to tertiary lymphoid organ (TLO) formation in mucosal organs following tissue damage remain unclear. Using a virus-induced model…”
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A Novel Role for Non-Neutralizing Antibodies against Nucleoprotein in Facilitating Resistance to Influenza Virus by Carragher, Damian M, Kaminski, Denise A, Moquin, Amy, Hartson, Louise, Randall, Troy D

“…Current influenza vaccines elicit Abs to the hemagglutinin and neuraminidase envelope proteins. Due to antigenic drift, these vaccines must be reformulated…”
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Contributions of antinucleoprotein IgG to heterosubtypic immunity against influenza virus by LaMere, Mark W, Lam, Ho-Tak, Moquin, Amy, Haynes, Laura, Lund, Frances E, Randall, Troy D, Kaminski, Denise A

“…Influenza A virus causes recurring seasonal epidemics and occasional influenza pandemics. Because of changes in envelope glycoprotein Ags, neutralizing Abs…”
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Defining Genetic Variation in Widely Used Congenic and Backcrossed Mouse Models Reveals Varied Regulation of Genes Important for Immune Responses by Chisolm, Danielle A., Cheng, Wayne, Colburn, Shelby A., Silva-Sanchez, Aaron, Meza-Perez, Selene, Randall, Troy D., Weinmann, Amy S.

“…Genetic variation influences how the genome is interpreted in individuals and in mouse strains used to model immune responses. We developed approaches to…”
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Mitochondrial calcium uniporter regulates PGC-1α expression to mediate metabolic reprogramming in pulmonary fibrosis by Gu, Linlin, Larson Casey, Jennifer L, Andrabi, Shaida A, Lee, Jun Hee, Meza-Perez, Selene, Randall, Troy D, Carter, A Brent

“…Idiopathic pulmonary fibrosis (IPF) is a progressive disease with an increased mortality. Metabolic reprogramming has a critical role in multiple chronic…”
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Epitope-Specific Regulation of Memory Programming by Differential Duration of Antigen Presentation to Influenza-Specific CD8+ T Cells by Ballesteros-Tato, André, León, Beatriz, Lee, Byung O., Lund, Frances E., Randall, Troy D.

“…Memory CD8+ T cells are programmed during the primary response for robust secondary responsiveness. Here we show that CD8+ T cells responding to different…”
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Ectopic lymphoid tissues and local immunity by Carragher, Damian M, Rangel-Moreno, Javier, Randall, Troy D

“…Abstract Ectopic or tertiary lymphoid tissues develop at sites of inflammation or infection in peripheral, non-lymphoid organs. These tissues are…”
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A Review of the Role of Wnt in Cancer Immunomodulation by Goldsberry, Whitney N, Londoño, Angelina, Randall, Troy D, Norian, Lyse A, Arend, Rebecca C

“…Alterations in the Wnt signaling pathway are associated with the advancement of cancers; however, the exact mechanisms responsible remain largely unknown. It…”
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IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung by Khader, Shabaana A, Guglani, Lokesh, Rangel-Moreno, Javier, Gopal, Radha, Junecko, Beth A Fallert, Fountain, Jeffrey J, Martino, Cynthia, Pearl, John E, Tighe, Michael, Lin, Yin-yao, Slight, Samantha, Kolls, Jay K, Reinhart, Todd A, Randall, Troy D, Cooper, Andrea M

“…IL-23 is required for the IL-17 response to infection with Mycobacterium tuberculosis, but is not required for the early control of bacterial growth. However,…”
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Immunological Functions of the Omentum by Meza-Perez, Selene, Randall, Troy D

“…The omentum is a visceral adipose tissue with unique immune functions. Although it is primarily an adipose tissue, the omentum also contains lymphoid…”
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The antitumor effects of entinostat in ovarian cancer require adaptive immunity by Smith, Haller J., McCaw, Tyler R., Londono, Angelina I., Katre, Ashwini A., Meza‐Perez, Selene, Yang, Eddy S., Forero, Andres, Buchsbaum, Donald J., Randall, Troy D., Straughn, Jr, J. Michael, Norian, Lyse A., Arend, Rebecca C.

“…Background Ovarian cancer is poorly immunogenic; however, increased major histocompatibility complex class II (MHCII) expression correlates with improved…”
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Profiling early lung immune responses in the mouse model of tuberculosis by Kang, Dongwan D, Lin, Yinyao, Moreno, Javier-Rangel, Randall, Troy D, Khader, Shabaana A

“…Tuberculosis (TB) is caused by the intracellular bacteria Mycobacterium tuberculosis, and kills more than 1.5 million people every year worldwide. Immunity to…”
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