Search Results - "Randò, T"

Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration by Sahu, A., Mamiya, H., Shinde, S. N., Cheikhi, A., Winter, L. L., Vo, N. V., Stolz, D., Roginskaya, V., Tang, W. Y., St. Croix, C., Sanders, L. H., Franti, M., Van Houten, B., Rando, T. A., Barchowsky, A., Ambrosio, F.

“…While young muscle is capable of restoring the original architecture of damaged myofibers, aged muscle displays a markedly reduced regeneration. We show that…”
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Assessment of visual function in children with methylmalonic aciduria and homocystinuria by Ricci, D, Pane, M, Deodato, F, Vasco, G, Randò, T, Caviglia, S, Dionisi-Vici, C, Mercuri, E

“…The aim of this study was to assess various aspects of visual function in 6 patients (age range: 9 months to 7 years and 8 months) with methylmalonic aciduria…”
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Preventing oxidative stress: a new role for XBP1 by Liu, Y, Adachi, M, Zhao, S, Hareyama, M, Koong, A C, Luo, Dan, Rando, T A, Imai, K, Shinomura, Y

“…Antioxidant molecules reduce oxidative stress and protect cells from reactive oxygen species (ROS)-mediated cellular damage and probably the development of…”
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Periodic lateralized epileptiform discharges (PLEDs) as early indicator of stroke in full-term newborns by Randò, T, Ricci, D, Mercuri, E, Frisone, M F, Luciano, R, Tortorolo, G, Guzzetta, F

“…We report on periodic lateralized epileptiform discharges (PLEDs) on EEG in two infants with neonatal convulsions. In both neonates, the EEG abnormalities were…”
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Use of a biological extracellular matrix wound therapy to heal complex, chronic wounds by Rando, T

“…This small case series involved four patients with vascular impairment and multiple comorbidities whose wounds had not responded to standard treatment. Use of…”
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Inhibition of dystroglycan binding to laminin disrupts the PI3K/AKT pathway and survival signaling in muscle cells by Langenbach, K.J., Rando, T.A.

“…Dystroglycan is a component of the dystrophin–glycoprotein complex (DGC) in muscle and a cell surface receptor for laminin. Numerous muscular dystrophies are…”
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Preventing oxidative stress: a new role for XBP1 by Liu, Y, Adachi, M, Zhao, S, Hareyama, M, Koong, A C, Luo, Dan, Rando, T A, Imai, K, Shinomura, Y

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Notch-Mediated Restoration of Regenerative Potential to Aged Muscle by Conboy, Irina M., Conboy, Michael J., Smythe, Gayle M., Rando, Thomas A.

“…A hallmark of aging is diminished regenerative potential of tissues, but the mechanism of this decline is unknown. Analysis of injured muscle revealed that,…”
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The Regulation of Notch Signaling Controls Satellite Cell Activation and Cell Fate Determination in Postnatal Myogenesis by Conboy, Irina M., Rando, Thomas A.

“…We have studied the role of Notch-1 and its antagonist Numb in the activation of satellite cells during postnatal myogenesis. Activation of Notch-1 promoted…”
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The dystrophin-glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies by Rando, Thomas A.

“…Mutations of different components of the dystrophin–glycoprotein complex (DGC) cause muscular dystrophies that vary in terms of severity, age of onset, and…”
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Primary Mouse Myoblast Purification, Characterization, and Transplantation for Cell-Mediated Gene Therapy by Rando, Thomas A., Blau, Helen M.

“…The transplantation of cultured myoblasts into mature skeletal muscle is the basis for a new therapeutic approach to muscle and non-muscle diseases:…”
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Epileptic disorders with onset in the first year of life: neurological and cognitive outcome by Battaglia, D., Randó, T., Deodato, F., Bruccini, G., Baglio, G., Frisone, M.F., Pantó, T., Tortorella, G., Guzzetta, F.

“…We examined prospectively a series of 150 children with epilepsy beginning in the first year of life. We classified the types of epilepsy into five categories:…”
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NFκB and AP-1 mediate transcriptional responses to oxidative stress in skeletal muscle cells by Zhou, Lucy Z.-H, Johnson, Alexandra P, Rando, Thomas A

“…The ability to induce cellular defense mechanisms in response to environmental challenges is a fundamental property of eukaryotic and prokaryotic cells. We…”
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Treatment of grief and mourning through EMDR: Conceptual considerations and clinical guidelines by Solomon, R.M, Rando, T.A

“…Abstract Introduction Eye Movement Desensitization and Reprocessing (EMDR) is an empirically-supported psychotherapeutic approach for treating trauma, which is…”
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Healthy healing and wound prevention by Price, K, Dyer, A, Rondo, T, Hickman, P

“…Critical to achieving best outcomes in any clinical setting is ensuring decision making in wound prevention and healthy healing of a wound, has successful…”
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Evidence of oxidative stress in mdx mouse muscle: Studies of the pre-necrotic state by Disatnik, Marie-Helene, Dhawan, Jyotsna, Yu, Yip, Beal, M.Flint, Whirl, Michelle M, Franco, Alexa A, Rando, Thomas A

“…Considerable evidence indicates that free radical injury may underlie the pathologic changes in muscular dystrophies from mammalian and avian species. We have…”
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Spontaneous intracranial hypotension : report of two cases and review of the literature by RANDO, T. A, FISHMAN, R. A

“…We report two patients with spontaneous intracranial hypotension. In addition to the cardinal features of a postural headache and a low CSF pressure, the…”
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Role of nitric oxide in the pathogenesis of muscular dystrophies: A "two hit" hypothesis of the cause of muscle necrosis by Rando, Thomas A.

“…Although the genetic and biochemical bases of many of the muscular dystrophies have been elucidated, the pathophysiological mechanisms leading to muscle cell…”
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G.P.6.07 Mycophenolate mofetil’s beneficial effects on skeletal muscle in the mdx mouse by Strober, J, Rando, T

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Tumor suppression by RNA from the 3' untranslated region of alpha-tropomyosin by Rastinejad, F, Conboy, M J, Rando, T A, Blau, H M

“…NMU2, a nondifferentiating mutant myogenic cell line, gives rise to rhabdomyosarcomas in mice. We show that constitutive expression of RNA from 0.2 kb of the…”
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