Search Results - "Ranasinghe, Maduni"

Suitability of double-stranded DNA as a molecular standard for the validation of analytical ultracentrifugation instruments by Ranasinghe, Maduni, Fogg, Jonathan M., Catanese, Daniel J., Zechiedrich, Lynn, Demeler, Borries

“…To address the current lack of validated molecular standards for analytical ultracentrifugation (AUC), we investigated the suitability of double-stranded DNA…”
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4S-fluorination of ProB29 in insulin lispro slows fibril formation by Breunig, Stephanie L., Chapman, Alex M., LeBon, Jeanne, Quijano, Janine C., Ranasinghe, Maduni, Rawson, Jeffrey, Demeler, Borries, Ku, Hsun Teresa, Tirrell, David A.

“…Recombinant insulin is a life-saving therapeutic for millions of patients affected by diabetes mellitus. Standard mutagenesis has led to insulin variants with…”
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DNA supercoiling-induced shapes alter minicircle hydrodynamic properties by Waszkiewicz, Radost, Ranasinghe, Maduni, Fogg, Jonathan M, Catanese, Daniel J, Ekiel-Jeżewska, Maria L, Lisicki, Maciej, Demeler, Borries, Zechiedrich, Lynn, Szymczak, Piotr

“…Abstract DNA in cells is organized in negatively supercoiled loops. The resulting torsional and bending strain allows DNA to adopt a surprisingly wide variety…”
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Photocatalytic Hydrogen Evolution by a De Novo Designed Metalloprotein that Undergoes Ni‐Mediated Oligomerization Shift by Prasad, Pallavi, Hunt, Leigh Anna, Pall, Ashley E., Ranasinghe, Maduni, Williams, Ashley E., Stemmler, Timothy L., Demeler, Borries, Hammer, Nathan I., Chakraborty, Saumen

“…De novo metalloprotein design involves the construction of proteins guided by specific repeat patterns of polar and apolar residues, which, upon self‐assembly,…”
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Molecular Standards for Analytical Ultracentrifugation: Investigating the Suitability of Double-Stranded DNA by Ranasinghe, Maduni Charuni

“…This thesis focuses on the development of molecular standards to validate analytical ultracentrifugation (AUC) instruments, alongside an exploration of…”
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